CAS 56-04-2

Metiltiouracil

Descrição:

Metiltiouracil, com o número CAS 56-04-2, é um composto orgânico que pertence à classe dos derivados do tiouracilo. É reconhecido principalmente por seu papel como agente antitireoidiano, utilizado no tratamento do hipertireoidismo ao inibir a síntese de hormônios tireoidianos. A fórmula molecular de Metiltiouracil é C7H8N2OS, e apresenta um grupo tiol, que contribui para sua atividade biológica. Este composto é tipicamente apresentado como um pó cristalino branco a off-white, e é solúvel em água e álcool, tornando-o acessível para várias formulações farmacêuticas. Metiltiouracil atua bloqueando a enzima tireoperoxidase, que é crucial para a iodação de resíduos de tirosina na tireoglobulina, reduzindo assim a produção de tiroxina (T4) e triiodotironina (T3). Além de suas aplicações terapêuticas, também é utilizado em ambientes de pesquisa para estudar a função tireoidiana e distúrbios relacionados. Devem ser observadas precauções de segurança ao manusear este composto, pois pode ter efeitos colaterais e interações com outros medicamentos.

Fórmula: C₅H₆N₂OS

InChI: InChI=1S/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)

Chave InChI: InChIKey=HWGBHCRJGXAGEU-UHFFFAOYSA-N

SMILES: CC1=CC(=O)NC(=S)N1

Sinónimos:

• 2,3-Dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone
• 2-Mercapto-4-methyl-6-hydroxypyrimidine
• 2-Mercapto-6-methyl-4-pyrimidinol
• 2-Mercapto-6-methylpyrimidin-4(3H)-one
• 2-Mercapto-6-methylpyrimidin-4-one
• 2-Mercapto-6-methylpyrimidyl-4-one
• 2-Thio-6-methyluracil
• 4(1H)-pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo-
• 4-Hydroxy-2-mercapto-6-methylpyrimidine
• 4-Hydroxy-6-methyl-2-mercaptopyrimidine
• 4-Hydroxy-6-methylpyrimidine-2(1H)-thione
• 4-Methyl-2-thiouracil
• 6-(methylsulfanyl)pyrimidine-2,4(1H,3H)-dione
• 6-Methyl-2-Sulfanylpyrimidin-4-Ol
• 6-Methyl-2-Thiouracyle
• 6-Methyl-2-mercaptouracil
• 6-Methyl-2-thio-2,4-(1H,3H)-pyrimidinedione
• 6-Methyl-2-thiouracil
• 6-Methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
• 6-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-on
• 6-Methyl-2-thioxopyrimidin-4-one
• 6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine
• 6-Thio-4-methyluracil
• 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
• Alkiron
• Antibason
• Basecil
• Basethyrin
• MTU
• Metacil
• Methacil
• Methiacil
• Methicil
• Methiocil
• Methiure
• Methylthiouracil
• Methylthiouracile
• Metiltiouracilo
• Metiur
• Muracil
• Muracin
• Nsc 193526
• Nsc 314271
• Nsc 9378
• Orcanon
• Prostrumyl
• Strumacil
• Thimecil
• Thiomecil
• Thiomidil
• Thioryl
• Thiothymin
• Thiothyron
• Thiuryl
• Thyreonorm
• Thyreostat
• Thyreostat I
• Thyril
• Tiomeracil
• Tiorale M
• Tiotiron
• Uracil, 2-Thio-4-Methyl-
• Uracil, 6-methyl-2-thio-

6-Methyl-2-thiouracil, 98%

CAS: 56-04-2

6-Methyl-2-thiouracil is mainly used in surgical preparation of mild hyperthyroidism, thyroid storm, hyperthyroidism and postoperative treatment. It is used in the treatment of hyperthyroidism. It is used as a drug, which is applied to decrease the formation of stored thyroid hormone and thyroglobul

Fórmula: C₅H₆N₂OS

Pureza: 98%

Cor e Forma: White to pale yellow, Powder

Peso molecular: 142.18

Ref: 02-A17982

Methylthiouracil

CAS: 56-04-2

Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.

Fórmula: C₅H₆N₂OS

Pureza: 98.82% - 99.89%

Cor e Forma: Solid

Peso molecular: 142.18

Ref: TM-T0304

6-Methyl-2-thiouracil

CAS: 56-04-2

6-Methyl-2-thiouracil

Fórmula: C₅H₆N₂OS

Pureza: ≥95%

Cor e Forma: Pale yellow Solid-Crystals

Peso molecular: 142.17894

Ref: 54-OR27585

Methylthiouracil

CAS: 56-04-2

Methylthiouracil

Fórmula: C₅H₆N₂OS

Pureza: ≥98%

Peso molecular: 142.18

Ref: 54-BUP11867

Methylthiouracil

Produto Controlado

CAS: 56-04-2

Fórmula: C₅H₆N₂OS

Cor e Forma: Neat

Peso molecular: 142.18

Ref: 86-MM3148.00

6-Methyl-2-thiouracil

CAS: 56-04-2

Fórmula: C₅H₆N₂OS

Pureza: >98.0%(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 142.18

Ref: 3B-M0443

6-Methyl-2-thiouracil

Produto Controlado

CAS: 56-04-2

Fórmula: C₅H₆N₂OS

Cor e Forma: Neat

Peso molecular: 142.18

Ref: 04-C15144300

6-​Methyl-​2-​thiouracil

Produto Controlado

CAS: 56-04-2

Applications 6-​Methyl-​2-​thiouracil is a derivative of methylthiouracil (M330710), a competitive inhibitor of Nitric Oxide Synthase (NOS). Potential anti-inflammatory agent.
References Palumbo, A. et al.: Biochem. Bioph. Res. Co. 282, 793(2001), Ku, S. et al.: Toxicol. App. Pharmacol., 288, 374 (2015);

Fórmula: C₅H₆N₂OS

Cor e Forma: Neat

Peso molecular: 142.18

Ref: TR-M331355

4-Hydroxy-2-mercapto-6-methy1-pyrimidine

CAS: 56-04-2

4-Hydroxy-2-mercapto-6-methylpyrimidine is a structural analysis of the molecule. It is a pyrimidine compound that has been found to be effective against human bowel disease and congestive heart failure, as well as in a model system of infectious diseases. 4-Hydroxy-2-mercapto-6-methylpyrimidine inhibits the activity of cyclin D2 by binding to it and preventing its attachment to the G1/S phase checkpoint. This compound also inhibits the activity of c. glabrata polymerase chain reaction (PCR) and human leukemia cells HL60 cells. 4-Hydroxy-2-mercapto-6-methylpyrimidine is an analytical method for xray diffraction data, which has been shown to have antibacterial properties due to its ability to inhibit methylthiouracil from being converted into thyroxine in the body.

Fórmula: C₅H₆N₂OS

Pureza: Min. 95%

Cor e Forma: White Clear Liquid

Peso molecular: 142.18 g/mol

Ref: 3D-FH34311

Methylthiouracil

CAS: 56-04-2

2-Mercapto-6-methylpyrimidin-4(1H)-one

Fórmula: C₅H₆N₂OS

Pureza: 98%

Peso molecular: 142.18

Ref: IN-DG21473

6-Methyl-2-thiouracil

CAS: 56-04-2

Fórmula: C₅H₆N₂OS

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 142.18

Ref: 10-F076835

6-Methyl-2-thiouracil-13C4

Produto Controlado

CAS: 56-04-2

Fórmula: C₄CH₆N₂OS

Cor e Forma: Neat

Peso molecular: 146.15

Ref: TR-M331357

Propylthiouracil EP Impurity B

CAS: 56-04-2

Fórmula: C₅H₆N₂OS

Peso molecular: 142.18

Ref: ST-EA-CP-P201002

4-Hydroxy-2-mercapto-6-methylpyrimidine

CAS: 56-04-2

Fórmula: C₅H₆N₂OS

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 142.1789

Ref: IN-DA0034DF