CAS 58546-54-6
:Gomisina A
Descrição:
Gomisina A é um composto natural classificado como um lignano, derivado principalmente do fruto da planta Schisandra chinensis, conhecido comumente por seus usos medicinais tradicionais. É caracterizado por sua complexa estrutura policíclica, que contribui à sua atividade biológica. Gomisina A exibe várias propriedades farmacológicas, incluindo efeitos antioxidantes, anti-inflamatórios e hepatoprotetores, tornando-o de interesse tanto na medicina tradicional quanto na farmacologia moderna. O composto tem sido estudado por seus potenciais efeitos neuroprotetores e sua capacidade de modular certas vias de sinalização, o que pode ter implicações para condições como doenças neurodegenerativas. Além disso, Gomisina A mostrou promessas em melhorar a função hepática e proteger contra danos ao fígado. Sua solubilidade e estabilidade em diferentes solventes podem variar, influenciando sua biodisponibilidade e eficácia em aplicações terapêuticas. No geral, Gomisina A representa uma área significativa de pesquisa em química de produtos naturais e farmacologia, destacando a importância dos compostos derivados de plantas na gestão da saúde e da doença.
Fórmula:C23H28O7
InChI:InChI=1S/C23H28O7/c1-12-7-13-8-16-20(30-11-29-16)22(28-6)17(13)18-14(10-23(12,2)24)9-15(25-3)19(26-4)21(18)27-5/h8-9,12,24H,7,10-11H2,1-6H3
Chave InChI:InChIKey=ZWRRJEICIPUPHZ-UHFFFAOYSA-N
SMILES:O(C)C1=C2C=3C(=CC(OC)=C(OC)C3OC)CC(C)(O)C(C)CC2=CC4=C1OCO4
Sinónimos:- (6R,7R)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
- (6S,7S)-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
- (6S,7S,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol
- 1,2,3,13-Tetramethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrobenzo[3',4']Cycloocta[1',2':4,5]Benzo[1,2-D][1,3]Dioxol-6-Ol
- Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6S,7S,13aR)-
- Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, stereoisomer
- Gomisin A
- Schisandrol B
- Schisantherinol B
- Tjn 101
- Wuweizi alcohol B
- Wuweizichun B
- benzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6R,7R)-
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Gomisin A
CAS:Fórmula:C23H28O7Pureza:>96.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:416.47Schisandrol B (Standard)
CAS:Schisandrol B (Standard) is a reference standard for research and analysis in studies involving Schisandrol B. 1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation.Fórmula:C23H28O7Cor e Forma:SolidPeso molecular:416.4642Schizandrol B
CAS:Gomisin A has anti-inflammatory, antihypertensive, neuroprotective, and anti-proliferation properties, it induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. Gomisin A inhibits COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation.Fórmula:C23H28O7Pureza:95%~99%Peso molecular:416.47Schisandrol B
CAS:Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Fórmula:C23H28O7Pureza:99.14% - 99.95%Cor e Forma:SolidPeso molecular:416.4642Schisandrol B
CAS:Ether alcohol phenolFórmula:C23H28O7Pureza:≥ 98.0 % (HPLC)Cor e Forma:PowderPeso molecular:416.47Schizandrol B
CAS:Produto ControladoSchizandrol B is a natural compound that has been shown to protect against oxidative stress and decrease the mitochondrial membrane potential. Schizandrol B inhibits human cyp3a4, which is an enzyme that metabolizes drugs. The linear calibration curve was able to be obtained from the signal pathways in human cells. The analytical method used was matrix effect-free. Experimental models were used to show that schizandrol B has an inhibitory effect on locomotor activity and skin tumor formation. It also has been found to be a substrate for p-gp, which transports drugs across the cell membrane, and can therefore alter absorption of drugs, including gomisin A. Schizandrol B also modulates enzyme activities in vitro as well as in vivo.Fórmula:C23H28O7Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:416.46 g/molSchizandrol B - Bio-X ™
CAS:Produto ControladoThis product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C23H28O7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:416.46 g/molSchisandrol B
CAS:(6S,7S,13aR)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-olFórmula:C23H28O7Pureza:99+%Peso molecular:416.46
