CAS 59-26-7

Tocainida

Descrição:

Tocainida é um composto farmacêutico utilizado principalmente como agente antiarrítmico, particularmente no tratamento de arritmias ventriculares. Pertence à classe de medicamentos conhecidos como bloqueadores de canais de sódio, que atuam inibindo a entrada de íons de sódio durante a fase de despolarização do potencial de ação cardíaco, estabilizando assim a membrana cardíaca e reduzindo a atividade elétrica anormal. Tocainida é caracterizado por sua fórmula química, que inclui um anel de piperidina, e é tipicamente administrado por via oral. A substância tem uma solubilidade moderada em água e é conhecida por sua toxicidade relativamente baixa em comparação com outros agentes antiarrítmicos. A farmacocinética de Tocainida envolve metabolismo hepático, e é excretado principalmente pelos rins. Embora seja eficaz, seu uso pode ser limitado por efeitos colaterais, como distúrbios gastrointestinais e potencial para discrasias sanguíneas. Devido a esses fatores, o monitoramento é essencial durante o tratamento. No geral, Tocainida representa uma opção importante no manejo de certas arritmias cardíacas, embora seu uso clínico tenha diminuído com o advento de novos agentes.

Fórmula: C₁₀H₁₄N₂O

InChI: InChI=1/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3

Chave InChI: InChIKey=NCYVXEGFNDZQCU-UHFFFAOYSA-N

SMILES: C(N(CC)CC)(=O)C=1C=CC=NC1

Sinónimos:

• Anacardone
• Astrocar
• Inicardio
• Kardiamid
• Leptamin
• Mediamid
• Niamine
• Nicamide
• Nicetamide
• Nicethamid
• Nicor
• Nicotinic Acid Diethyl Amide
• Nikethamide
• Nikotin
• N,N-diethyl-3-pyridinecarboxamide
• N,N-Diethylnicotinamide
• Percoral
• Procardine
• Pyridine-3-Carboxyldiethylamide
• Pyridine-3-Carboxylic Acid Diethylamide
• Reformin
• Salvacord
• Stellamine
• Stimulin
• Vasozol
• Diethyl-Nicotamide
• Dietilamide-Carbopiridina
• Dinacoryl
• Betapyrimidum
• Camphozone
• Cardiamid
• Cardiamine
• Cardamine
• Citocor
• Coracon
• Coraethamidum
• Coramine
• Corazone
• Cordiamin
• Cordynil
• Corediol
• Coretone
• Cormid
• Cornotone
• Corvitan
• Corvotone
• Danamine
• Elitone
• Hansacor
• N,N-diethylpyridine-3-carboxamide
• 3-(N,N-Diethylcarbamoyl)pyridine
• 3-Pyridinecarboxamide, N,N-diethyl-
• Anacordone
• Canfodiamina
• Carbamidal
• Cardiamide
• Cardimon
• Coractiv N
• Coramine (pharmaceutical)
• Cordiamine
• Cormed
• Cormotyl
• Corvin
• Corvitol
• Diethylnicotinamide
• Dynacoryl
• Ecoran
• Eucoran
• Kordiamin
• Nicetamida
• Nicethamide
• Ni-Cor
• Nicorine
• Nicotinamide, N,N-diethyl-
• Nicotinic acid diethylamide
• Nikardin
• Niketamide
• Niketamine
• Nikethamid
• Niketharol
• Nikethyl
• Nikorin
• Niquetamide
• Nsc 130820
• Nsc 169863
• Nsc 62103
• Pyricardyl
• Pyridine-3-carboxydiethylamide
• Rehormin
• Salvacard
• Sancora
• Solyacord
• Ventramine
• Nickethamide
• NIKETHAMIDUM
• LABOTEST-BB LT00134638

N,N-Diethylnicotinamide

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Pureza: >98.0%(GC)(T)

Cor e Forma: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Peso molecular: 178.24

Ref: 3B-D0514

NIKETHAMIDE CRS

CAS: 59-26-7

NIKETHAMIDE CRS

Fórmula: C₁₀H₁₄N₂O

Cor e Forma: May Be Present In Various Forms. Oily Liquid. Crystalline Mass. Yellow. Transparent.

Peso molecular: 178.231

Ref: 41-N0800000

N,N-Diethylnicotinamide

CAS: 59-26-7

N,N-Diethylnicotinamide

Fórmula: C₁₀H₁₄N₂O

Pureza: 97%

Peso molecular: 178.23095

Ref: 54-OR926552

Nikethamide

CAS: 59-26-7

Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of end

Fórmula: C₁₀H₁₄N₂O

Pureza: 99.42%

Cor e Forma: Solid

Peso molecular: 178.23

Ref: TM-T0048

Nikethamide

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Pureza: ≥ 98.0%

Cor e Forma: Colourless or pale yellow oily liquid, or crystalline mass

Peso molecular: 178.23

Ref: 7W-GP1304

Nikethamide, EP grade

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Pureza: 99.0 - 101.0 % (anhydrous substance)

Cor e Forma: An oily liquid or a crystalline mass, colourless or pale yellow

Peso molecular: 178.23

Ref: 7W-GP1011

Nikethamide

CAS: 59-26-7

Cor e Forma: Off-White

Ref: 04-C15525900

Nikethamide

Produto Controlado

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Cor e Forma: Off-White

Peso molecular: 178.23

Ref: 86-MM0627.00

N,N-Diethylnicotinamide (Nikethamide)

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Peso molecular: 178.24

Ref: 4Z-N-133029

N,N-Diethylnicotinamide (Nikethamide)

CAS: 59-26-7

Applications Nikethamide is an analeptic agent. It was used in the mid-twentieth century as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now considered to be of no value for such purposes, and may in fact be dangerous.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bean, J., et al.: Biochem. Pharm., 35, 1011 (1986); Chakaravarti, M.: J. Pharmacol., 67, 153 (1939); Naik, S., et al.: Biochem. Pharm., 18, 2038 (1969); Martindale, The Extra Pharmacopoeia, 30th ed,, 1229

Fórmula: C₁₀H₁₄N₂O

Cor e Forma: Neat

Peso molecular: 178.23

Ref: TR-N460000

N,N-Diethylnicotinamide

Produto Controlado

CAS: 59-26-7

N,N-Diethylnicotinamide is a nicotinamide derivative that is used as an anti-inflammatory agent. It has been shown to inhibit the activity of enzymes such as acetylcholinesterase, phospholipase A2, and cyclooxygenase. N,N-Diethylnicotinamide has a synergistic effect with pentobarbital sodium in inducing chronic pulmonary inflammation in rats. This drug also has an acid complexing effect on fatty acids and nitrogen atoms. The coordination geometry of this drug is octahedral with two nitrogen atoms coordinated to one metal ion. N,N-Diethylnicotinamide can be synthesized by reacting nicotinic acid with diethylamine in the presence of 1 equivalent of hydrogen gas.

Fórmula: C₁₀H₁₄N₂O

Pureza: Min. 95%

Cor e Forma: Colorless Clear Liquid

Peso molecular: 178.23 g/mol

Ref: 3D-FD31942

N.N-Diethylnicotinamide in Methanol

CAS: 59-26-7

Methanol

Ref: BE-BePure-24370XM-100

N,N-Diethylnicotinamide

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Peso molecular: 178.24

Ref: ST-EA-CP-N35013