CAS: 606143-52-6 - Selumetinib

Fórmula: C₁₇H₁₅BrClFN₄O₃

InChI: InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)

Chave InChI: InChIKey=CYOHGALHFOKKQC-UHFFFAOYSA-N

SMILES: O=C(NOCCO)C1=CC2=C(N=CN2C)C(F)=C1NC3=CC=C(Br)C=C3Cl

Sinónimos:

• 1H-Benzimidazole-6-carboxamide, 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-
• 5-(4-Bromo-2-chlorophenylamino)-4-fluoro-1-methyl-1H-benzimidazole-6-carbohydroxamic acid 2-hydroxyethyl ester
• 5-[(4-Bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide
• 6-(4-Bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
• Arry-142886
• Azd 6244
• Azd-6224
• Azd6244
• G 00039805
• Koselugo
• NSC 741O78
• Zd-6244

Selumetinib

CAS: 606143-52-6

• Cor e Forma: White To Off White Solid
• Peso molecular: 457.68g/mol

Selumetinib

CAS: 606143-52-6

Selumetinib (AZD6244) (AZD6244) is an effective, specific inhibitor of MEK1 and ERK1/2 phosphorylation (IC50: 14/10 …

• Fórmula: C₁₇H₁₅BrClFN₄O₃
• Pureza: 99%
• Cor e Forma: White Or Pale White Solid
• Peso molecular: 457.68

Selumetinib

CAS: 606143-52-6

5-[(4-Bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide

CAS: 606143-52-6

• Pureza: 99.0%
• Peso molecular: 457.67999267578125

Selumetinib

CAS: 606143-52-6

Potent and selective MAP/ERK kinase 1/2 inhibitor. Reduces growth of tumor cells with B-Raf and …

• Fórmula: C₁₇H₁₅BrClFN₄O₃
• Pureza: Min. 98 Area-%
• Cor e Forma: White Powder
• Peso molecular: 457.68 g/mol

Selumetinib

CAS: 606143-52-6

Applications It is a tight-binding, uncompetitive inhibitor of mitogen-activated protein kinase kinases (MEK) 1 and …

• Fórmula: C₁₇H₁₅BrClFN₄O₃
• Cor e Forma: Neat
• Peso molecular: 457.68