CAS 607373-46-6

Fórmula: C15H20Cl2N8O2

InChI: InChI=1S/C15H18N8O2.2ClH/c1-2-23-12-9(15(24)22-4-3-8(16)7-22)5-18-6-10(12)19-14(23)11-13(17)21-25-20-11;;/h5-6,8H,2-4,7,16H2,1H3,(H2,17,21);2*1H/t8-;;/m0../s1

Chave InChI: HSROPTGRSYJPJY-JZGIKJSDSA-N

SMILES: CCN1C2=C(C=NC=C2C(=O)N3CC[C@@H](C3)N)N=C1C4=NON=C4N.Cl.Cl

(S)-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl)(3-aminopyrrolidin-1-yl)methanone dihydrochloride

CAS: 607373-46-6

(S)-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl)(3-aminopyrrolidin-1-yl)methanone dihydrochloride

Fórmula: C₁₅H₂₀Cl₂N₈O₂

Pureza: 98%

Peso molecular: 415.29

Ref: 54-OR1067158

SB-772077B (hydrochloride)

CAS: 607373-46-6

Pureza: 98%

Ref: IN-DA00ELVO

SB-772077B 2HCl

CAS: 607373-46-6

(S)-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl)(3-aminopyrrolidin-1-yl)methanone dihydrochloride

Fórmula: C₁₅H₂₀Cl₂N₈O₂

Pureza: 98%

Peso molecular: 415.28

Ref: IN-DG01402202

SB-772077B dihydrochloride

CAS: 607373-46-6

SB-772077B is a novel blocker that is being developed for the treatment of various diseases. The drug blocks angiotensin II type 1 receptors and has been shown to suppress tumour growth in a cell culture model. SB-772077B also inhibits the proliferation of pluripotent cells, which may be useful in the development of treatments for autoimmune diseases. This drug has been validated by assays that show it prevents organoid formation and organoids from growing. SB-772077B also blocks angiotensin II type 1 receptors and has been shown to suppress tumour growth in a cell culture model. SB-772077B also inhibits the proliferation of pluripotent cells, which may be useful in the development of treatments for autoimmune diseases.

Fórmula: C₁₅H₂₀Cl₂N₈O₂

Pureza: Min. 95%

Peso molecular: 415.28 g/mol

Ref: 3D-HZA37346

SB-772077B dihydrochloride

CAS: 607373-46-6

SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).

Fórmula: C₁₅H₂₀Cl₂N₈O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 415.28

Ref: TM-T16855