CAS 61318-91-0

nitrato de sulconazol

Descrição:

nitrato de sulconazol é um agente antifúngico utilizado principalmente no tratamento de infecções dermatológicas, particularmente aquelas causadas por fungos e leveduras. Pertence à classe de derivados imidazólicos, que são conhecidos por sua capacidade de inibir a síntese de ergosterol, um componente crítico das membranas celulares fúngicas. Esse mecanismo interrompe a integridade da célula fúngica, levando à morte celular. nitrato de sulconazol é tipicamente formulado como um creme ou solução tópica, permitindo um tratamento localizado com mínima absorção sistêmica. O composto é caracterizado por sua relativamente baixa solubilidade em água, o que aumenta sua eficácia em aplicações tópicas. Além disso, exibe um amplo espectro de atividade antifúngica contra vários patógenos, tornando-se uma opção valiosa em ambientes clínicos. Os perfis de segurança indicam que geralmente é bem tolerado, com efeitos colaterais sendo raros e tipicamente leves. Assim como qualquer medicamento, é essencial usar nitrato de sulconazol conforme indicado por um profissional de saúde para garantir resultados terapêuticos ideais e minimizar o risco de desenvolvimento de resistência.

Fórmula: C₁₈H₁₆Cl₃N₃O₃S

InChI: InChI=1/C18H15Cl3N2S.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

Chave InChI: InChIKey=CRKGMGQUHDNAPB-UHFFFAOYSA-N

SMILES: C(CN1C=CN=C1)(SCC2=CC=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3.N(=O)(=O)O

Sinónimos:

• 1-[2-(4-Chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, (±)-, mononitrate
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1)
• Exelderm
• Rs 44872
• Rs 44872-00-10-3
• Sulcosyn
• Sulconazole nitrate
• Myk
• rs44872
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (9CI)
• Sulconazole Nitrate (200 mg)
• 1-(2-(((4-chlorophenyl)methyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazol
• SULCONAZOLE NITRATE SALT
• ,mononitrate,(+-)-
• Sulconazole (mononitrate)
• Sulconazole nitrate,cas:61318-91-0
• 1H-IMidazole, 1-[2-[[(4-chlorophenyl)Methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate
• 1-[2-(P-CHLOROBENZYLTHIO)-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE NITRATE
• Sulconazole nitrate salt,1-(2-[p-Chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole
• Sulconazole nitrate USP/EP/BP
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, mononitrate (9CI)
• (+-)-1-(2,4-dichloro-beta-((4-chlorobenzyl)thio)phenethyl)imidazolenitrate
• 1-(2-[p-chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1h-imidazole
• 1-[2-[(4-chlorophenyl)methylthio]-2-(2,4-dichlorophenyl)ethyl]imidazole

Sulconazole Nitrate

CAS: 61318-91-0

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Pureza: >98.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 460.75

Ref: 3B-U0112

Sulconazole Nitrate

CAS: 61318-91-0

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi

Fórmula: C₁₈H₁₅Cl₃N₂S

Cor e Forma: White Off-White Powder

Peso molecular: 396.00215

Ref: 45-1623681

Sulconazole Nitrate

CAS: 61318-91-0

Sulconazole Nitrate

Fórmula: C₁₈H₁₅Cl₃N₂SHNO₃

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 460.75

Ref: 54-OR1030138

Sulconazole mononitrate

CAS: 61318-91-0

Sulconazole mononitrate

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Pureza: 99.5%

Peso molecular: 460.76

Ref: 54-BUP13871

Sulconazole nitrate salt

CAS: 61318-91-0

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Pureza: ≥ 98.0%

Cor e Forma: White powder

Peso molecular: 460.76

Ref: 7W-GA8662

Sulconazole Nitrate

Produto Controlado

CAS: 61318-91-0

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Cor e Forma: Neat

Peso molecular: 460.76

Ref: 86-MM3674.00

Sulconazole mononitrate

CAS: 61318-91-0

"Sulconazole mononitrate (Exelderm) is a synthetic antifungal imidazole that disrupts fungal cell membranes by inhibiting ergosterol synthesis."

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Pureza: 99.68% - 99.75%

Cor e Forma: White Solid

Peso molecular: 460.76

Ref: TM-T6686

Sulconazole Nitrate

Produto Controlado

CAS: 61318-91-0

Applications Sulconazole Nitrate is an antifungal agent which prevents fungal growth by inhibiting sterol synthesis.
References Kinobe, R. et al.: J. Pharmacol. Exp. Ther., 319, 277 (2006); Ooishi, T. et al.: J. Japan. Soc. Hosp. Pharm., 31, 1449 (1995);

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Cor e Forma: Neat

Peso molecular: 460.76

Ref: TR-S688940

SULCONAZOLENITRATE

CAS: 61318-91-0

Fórmula: C₁₈H₁₆Cl₃N₃O₃S

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 460.7619

Ref: IN-DA00IAU9

Sulconazole Nitrate

CAS: 61318-91-0

Sulconazole Nitrate is a broad-spectrum antimicrobial agent that inhibits the growth of fungi by interfering with the synthesis of ergosterol, an important component of fungal cell membranes. Sulconazole Nitrate has been shown to possess in vitro antifungal activity against dimorphic fungi such as Candida albicans and Cryptococcus neoformans. It also has been shown to inhibit the growth of bacteria and other microbes through inhibition of fatty acid synthesis. This drug may be used as an adjuvant therapy for autoimmune diseases or infections caused by resistant strains of bacteria. Sulconazole Nitrate binds to fatty acids in the plasma membrane and prevents their incorporation into the phospholipid bilayer. The disruption of this process results in decreased cell membrane fluidity, which leads to a loss of structural integrity and cell permeability.

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Pureza: Min. 95%

Peso molecular: 460.76 g/mol

Ref: 3D-FS76681