CAS 633-65-8

Cloridrato de berberina

Descrição:

Cloridrato de berberina é um sal de amônio quaternário derivado do alcaloide berberina, que é encontrado em várias plantas, incluindo goldenseal e agracejo. É caracterizado por sua cor amarelo brilhante e é conhecido por seu sabor amargo. A substância é solúvel em água e álcool, tornando-a adequada para várias formulações farmacêuticas. Cloridrato de berberina exibe uma gama de atividades biológicas, incluindo propriedades antimicrobianas, anti-inflamatórias e antidiabéticas, que despertaram interesse tanto na medicina tradicional quanto na moderna. Seu mecanismo de ação envolve a modulação de várias vias celulares, incluindo aquelas relacionadas ao metabolismo da glicose e à regulação de lipídios. Além disso, a berberina tem sido estudada por seus potenciais efeitos na saúde cardiovascular e na microbiota intestinal. Devido aos seus diversos efeitos farmacológicos, Cloridrato de berberina é frequentemente utilizado em suplementos dietéticos e remédios à base de plantas, embora seu uso deva ser abordado com cautela devido a possíveis interações com outros medicamentos e efeitos colaterais. No geral, Cloridrato de berberina é um composto de interesse significativo tanto em contextos de pesquisa quanto terapêuticos.

Fórmula: C₂₀H₁₈ClNO₄

InChI: InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;

Chave InChI: InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M

SMILES: O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC.[Cl-]

Sinónimos:

• 1,3-Benzodioxolo[5,6-A]Benzo[G]Quinolizinium, 5,6-Dihydro-9,10-Dimethoxy-, Hydrochloride (1:1)
• 16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride
• Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
• Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)
• Berberberberine hydrochloride n-hydrate
• Berberine IR
• Berberine chloride
• Berberine hcl
• Berberinium chloride
• Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride
• NSC 163088
• NSC 646666
• ine HCl
• Berberine hydrochloride
• Berberine chloride form,Natural Yellow18
• 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-berbiniuchlori
• Berberine chloride form
• Berberine chloride ,98%
• Kyoberin
• Berberine hydrochloride hydrate,97%
• Berberdine HCl
• BERBERINECHLORIDE(SH)
• 9,10-Dimethoxy-5,6-dihydro-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
• BERBERINE CHLORIDE(AHP)
• 9,10-Dimethoxy-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
• berberiniumchloride
• NATURAL YELLOW 18
• BERBERIN HCL
• UMBELLATINE
• TIMTEC-BB SBB006488
• LABOTEST-BB LT00440956
• C.I.Natural Yellow 18
• Berberine Chloride, JP
• 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE
• BBR
• BERBERINE HYDROCHLORIDE N-HYDRATE
• 7,8,13,13a-Tetradehydro-9,10-diMethoxy-2,3-(Methylenedioxy)berbiniuM Chloride
• Berberin chloride dihydrate
• Berberinehydrochloride，Berberine chloride form
• 3)benzodioxolo(5,6-a)quinolizinium,5,6-dihydro-9,10-dimethoxy-benzo(g)(c
• 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
• NATURAL YELLOW 18 CHLORIDE
• Berberine chloride (TN)
• CI 75160

Berberine chloride

CAS: 633-65-8

Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical r

Fórmula: C₂₀H₁₈ClNO₄

Cor e Forma: Yellow to orange, Powder

Peso molecular: 371.82

Ref: 02-J62311

BERBERINE CHLORIDE CRS

CAS: 633-65-8

BERBERINE CHLORIDE CRS

Fórmula: C₂₀H₁₉ClNO₄

Peso molecular: 372.8216

Ref: 41-Y0001149

Berberine chloride

CAS: 633-65-8

Berberine chloride

Fórmula: C₂₀H₁₈NO₄

Pureza: 77.7%

Cor e Forma: White

Peso molecular: 336.12358

Ref: 47-1108

Berberine chloride

CAS: 633-65-8

Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 99.47% - 99.93%

Cor e Forma: Yellow Crystalline Powder

Peso molecular: 371.80

Ref: TM-T0461

Berberine chloride

CAS: 633-65-8

Berberine chloride

Fórmula: C₂₀H₁₈ClNO₄

Pureza: ≥98%

Cor e Forma: Solid

Peso molecular: 371.8

Ref: 54-BUP19732

Berberine hydrochloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 96.0 - 104.0 % (dried basis)

Cor e Forma: Yellow or orange powder

Peso molecular: 371.82

Ref: 7W-GK8292

Berberine hydrochloride

CAS: 633-65-8

Berberine hydrochloride

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 371.81

Ref: 54-OR1028076

Berberine hydrochloride

CAS: 633-65-8

Berberine hydrochloride (berberine), a natural plant alkaloid derived from Chinese herbal medicine, is characterized by diverse pharmacological effects, such as anticancer and lower elevated blood glucose, it can prevent adhesion by downregulating ICAM-1 and reduce inflammation by inhibiting the TAK1/JNK and TAK1/NF-κB signaling after abdominal surgery, which brings out a good therapeutic approach for the development of clinical application for postoperative abdominal adhesion and inflammation.

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 95%~99%

Cor e Forma: Powder

Peso molecular: 371.817

Ref: BP-BP0252

Berberine Chloride

Produto Controlado

CAS: 633-65-8

Fórmula: C₂₀H₁₈NO₄·Cl

Cor e Forma: Neat

Peso molecular: 371.81

Ref: 86-MM1632.00

Berberine chloride

CAS: 633-65-8

Berberine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₂₀H₁₈ClNO₄

Pureza: (HPLC) ≥95%

Cor e Forma: Powder

Peso molecular: 371.82

Ref: 11-0601

Berberine chloride

Produto Controlado

CAS: 633-65-8

Fórmula: C₂₀H₁₈NO₄·Cl

Cor e Forma: Neat

Peso molecular: 371.81

Ref: 04-C10573950

9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 371.8142

Ref: IN-DA00IB6S

Berberine chloride (Standard)

CAS: 633-65-8

Berberine chloride (Standard) is a reference standard for research and analysis in studies involving Berberine chloride. Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used orally for various fungal and parasitic infections and an anti-diarrheal.

Fórmula: C₂₀H₁₈ClNO₄

Cor e Forma: Solid

Peso molecular: 371.80

Ref: TM-TMSM-2973

Berberine hydrochloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 95.0%

Cor e Forma: Solid

Peso molecular: 371.82

Ref: 10-F516404

Berberine Chloride Hydrate

Produto Controlado

CAS: 633-65-8

Stability Hygroscopic
Applications An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);

Fórmula: C₂₀H₁₈NO₄·Cl

Cor e Forma: Neat

Peso molecular: 371.81

Ref: TR-B318150

Berberine Hydrochloride-d6

Produto Controlado

CAS: 633-65-8

Stability Hygroscopic
Applications Berberine Hydrochloride-d6 is labelled Berberine Hydrochloride (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);

Fórmula: C₂₀H₁₂D₆ClNO₄

Cor e Forma: Neat

Peso molecular: 377.85

Ref: TR-B318152

Berberine Hydrochloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈ClNO₄

Peso molecular: 371.8

Ref: BE-RMT20800

Berberine chloride

CAS: 633-65-8

9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 97%

Peso molecular: 371.81

Ref: IN-DG21926

Berberine Chloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈NO₄Cl

Peso molecular: 336.4 : 35.5

Ref: ST-EA-CP-B118001