CAS 633-65-8
:Cloridrato de berberina
Descrição:
Cloridrato de berberina é um sal de amônio quaternário derivado do alcaloide berberina, que é encontrado em várias plantas, incluindo goldenseal e agracejo. É caracterizado por sua cor amarelo brilhante e é conhecido por seu sabor amargo. A substância é solúvel em água e álcool, tornando-a adequada para várias formulações farmacêuticas. Cloridrato de berberina exibe uma gama de atividades biológicas, incluindo propriedades antimicrobianas, anti-inflamatórias e antidiabéticas, que despertaram interesse tanto na medicina tradicional quanto na moderna. Seu mecanismo de ação envolve a modulação de várias vias celulares, incluindo aquelas relacionadas ao metabolismo da glicose e à regulação de lipídios. Além disso, a berberina tem sido estudada por seus potenciais efeitos na saúde cardiovascular e na microbiota intestinal. Devido aos seus diversos efeitos farmacológicos, Cloridrato de berberina é frequentemente utilizado em suplementos dietéticos e remédios à base de plantas, embora seu uso deva ser abordado com cautela devido a possíveis interações com outros medicamentos e efeitos colaterais. No geral, Cloridrato de berberina é um composto de interesse significativo tanto em contextos de pesquisa quanto terapêuticos.
Fórmula:C20H18ClNO4
InChI:InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;
Chave InChI:InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M
SMILES:O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC.[Cl-]
Sinónimos:- 1,3-Benzodioxolo[5,6-A]Benzo[G]Quinolizinium, 5,6-Dihydro-9,10-Dimethoxy-, Hydrochloride (1:1)
- 16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride
- Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
- Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)
- Berberberberine hydrochloride n-hydrate
- Berberine IR
- Berberine chloride
- Berberine hcl
- Berberinium chloride
- Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride
- NSC 163088
- NSC 646666
- ine HCl
- Berberine hydrochloride
- Berberine chloride form,Natural Yellow18
- 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-berbiniuchlori
- Berberine chloride form
- Berberine chloride ,98%
- Kyoberin
- Berberine hydrochloride hydrate,97%
- Berberdine HCl
- BERBERINECHLORIDE(SH)
- 9,10-Dimethoxy-5,6-dihydro-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
- BERBERINE CHLORIDE(AHP)
- 9,10-Dimethoxy-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
- berberiniumchloride
- NATURAL YELLOW 18
- BERBERIN HCL
- UMBELLATINE
- TIMTEC-BB SBB006488
- LABOTEST-BB LT00440956
- C.I.Natural Yellow 18
- Berberine Chloride, JP
- 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE
- BBR
- BERBERINE HYDROCHLORIDE N-HYDRATE
- 7,8,13,13a-Tetradehydro-9,10-diMethoxy-2,3-(Methylenedioxy)berbiniuM Chloride
- Berberin chloride dihydrate
- Berberinehydrochloride，Berberine chloride form
- 3)benzodioxolo(5,6-a)quinolizinium,5,6-dihydro-9,10-dimethoxy-benzo(g)(c
- 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
- NATURAL YELLOW 18 CHLORIDE
- Berberine chloride (TN)
- CI 75160
- Ver mais sinónimos
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Foram encontrados 19 produtos.
Berberine Chloride Hydrate
CAS:Fórmula:C20H18ClNO4·xH2OPureza:>98.0%(T)(HPLC)Cor e Forma:White to Yellow to Orange powder to crystalinePeso molecular:371.82 (as Anhydrous)Berberine chloride
CAS:Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical rFórmula:C20H18ClNO4Cor e Forma:Yellow to orange, PowderPeso molecular:371.82Berberine chloride
CAS:Berberine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Fórmula:C20H18ClNO4Pureza:(HPLC) ≥95%Cor e Forma:PowderPeso molecular:371.82Berberine chloride
CAS:Berberine chlorideFórmula:C20H18NO4Pureza:77.7%Cor e Forma:WhitePeso molecular:336.12358Berberine chloride
CAS:Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.Fórmula:C20H18ClNO4Pureza:99.47% - 99.93%Cor e Forma:Yellow Crystalline PowderPeso molecular:371.80Berberine hydrochloride
CAS:Fórmula:C20H18ClNO4Pureza:96.0 - 104.0 % (dried basis)Cor e Forma:Yellow or orange powderPeso molecular:371.82Berberine hydrochloride
CAS:Berberine hydrochlorideFórmula:C20H18ClNO4Pureza:98%Cor e Forma:SolidPeso molecular:371.81Berberine chloride (Standard)
CAS:Berberine chloride (Standard) is a reference standard for research and analysis in studies involving Berberine chloride. Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used orally for various fungal and parasitic infections and an anti-diarrheal.Fórmula:C20H18ClNO4Cor e Forma:SolidPeso molecular:371.80Berberine hydrochloride
CAS:Berberine hydrochloride (berberine), a natural plant alkaloid derived from Chinese herbal medicine, is characterized by diverse pharmacological effects, such as anticancer and lower elevated blood glucose, it can prevent adhesion by downregulating ICAM-1 and reduce inflammation by inhibiting the TAK1/JNK and TAK1/NF-κB signaling after abdominal surgery, which brings out a good therapeutic approach for the development of clinical application for postoperative abdominal adhesion and inflammation.Fórmula:C20H18ClNO4Pureza:95%~99%Cor e Forma:PowderPeso molecular:371.817Berberine Hydrochloride-d6
CAS:Produto ControladoStability Hygroscopic
Applications Berberine Hydrochloride-d6 is labelled Berberine Hydrochloride (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);Fórmula:C20H12D6ClNO4Cor e Forma:NeatPeso molecular:377.85Berberine Chloride Hydrate
CAS:Produto ControladoStability Hygroscopic
Applications An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);Fórmula:C20H18NO4·ClCor e Forma:NeatPeso molecular:371.81Berberine chloride
CAS:Activates AMPK enzyme; anti-inflammatory; anti-diabeticFórmula:C20H18NO4•ClPureza:Min. 95%Cor e Forma:PowderPeso molecular:371.81 g/mol
