CAS 63968-64-9
:Artemisinina
Descrição:
Artemisinina é uma lactona sesquiterpênica com a fórmula química C15H22O5, derivada principalmente da planta de absinto doce, Artemisia annua. É conhecida por suas potentes propriedades antimaláricas e é um componente chave nas terapias combinadas baseadas em Artemisinina (ACT) usadas para tratar a malária. O composto apresenta uma ponte endoperóxido única, que é crucial para sua atividade biológica. Artemisinina exibe solubilidade moderada em solventes orgânicos como etanol e clorofórmio, mas tem solubilidade limitada em água. Seu mecanismo de ação envolve a geração de espécies reativas de oxigênio após ativação pelo heme, levando à destruição dos parasitas da malária. Artemisinina é geralmente bem tolerado, embora possa causar efeitos colaterais como náuseas e tontura em alguns pacientes. Devido à sua origem natural e eficácia, a pesquisa continua na otimização de seus derivados e na melhoria de suas propriedades farmacológicas. Além disso, estudos em andamento estão explorando suas potenciais aplicações além da malária, incluindo seus efeitos em vários tipos de câncer e outras doenças.
Fórmula:C15H22O5
InChI:InChI=1/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14+,15-/m1/s1
Chave InChI:InChIKey=BLUAFEHZUWYNDE-NNWCWBAJSA-N
SMILES:C[C@@H]1[C@]2([C@]34[C@@](O[C@](C)(OO3)CC[C@]4([C@H](C)CC2)[H])(OC1=O)[H])[H]
Sinónimos:- (+)-Arteannuin
- (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
- (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one
- (3S,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
- (5aS,6R,8aS,9R,12S)-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
- 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,12S,12aR)-
- 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, [3R-(3α,5aβ,6β,8aβ,9α,12β,12aR*)]-
- 3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
- ARTIVeda
- Artemef
- Artemisine
- Artemisinine
- Hc 101A
- Huanghuahaosu
- NSC 369397
- PulmoHeal
- Qing Hau Sau
- Qing Hau Su
- Qinghaosu
- Qinghosu
- [3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-one
- Artemisinin
- Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10(3H)-one
- ARTEANUIN
- (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12ar*)-(+)-methyl
- Artemisinin Qinghaosu/ [3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-one
- ARTEMISININ (QINGHAOSU)
- SWEET WORMWOOD
- artemisiaannual.,extract
- ARTEMETHER
- 3,12-epoxy-12h-pyranol(4,3-j)-1,2-benzodioxepin-10(3h)-one,octahydro-3,6,9-tri
- ArteMisinin, 98%, froM ArteMisia annua L.
- qinghausau
- ARTEMISININ 99%
- 3,13-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)one,(ctahydro-3,6,9-trimethyl-,[3R-(3α,5αβ,6β,8αβ,9α,12β,12αR*)]-
- Arteannuin99%
- (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epox12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one
- Artemisinine,98%
- QHS
- Astemisinin
- Arteannuin, Qinghaosu
- ARTEMISIA P E
- QINGHAOSA
- octahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano(4,3-j)-1,2-benzodioxepin-10(
- ALPHA BETA ARTEMISININ
- Quinghaosu
- qinghausu
- ArteMisinin, froM ArteMisia annua
- 3,12-Epoxy-12H-pyranol(4,3-j)-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12aR*)-(+)
- (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3 ,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one
- ARTEMISIA ANNUA
- Artemisine，Artemisinin，Arteannuin
- Artemisia annual L Ext.
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Foram encontrados 19 produtos.
Artemisinin
CAS:Fórmula:C15H22O5Pureza:>97.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:282.34Artemisinin, 98%
CAS:Artemisinin inhibits angiogenesis by down-regulating HIF-1 and VEGF expression in mouse embryonic stem cells. Artemisinin crosses the blood-brain barrier and is an inhibitor of human NOS2 (iNOS). This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio.Fórmula:C15H22O5Pureza:98%Cor e Forma:Crystals or crystalline powder, WhitePeso molecular:282.34Artemisinin
CAS:Heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFórmula:C15H22O5Cor e Forma:White Off-White SolidPeso molecular:282.14672(1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-one
CAS:Fórmula:C15H22O5Pureza:98%Cor e Forma:SolidPeso molecular:282.3322Artemisinin
CAS:Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.Fórmula:C15H22O5Pureza:99.77% - 99.87%Cor e Forma:SolidPeso molecular:282.33Artemisinin
CAS:Fórmula:C15H22O5Pureza:(HPLC) ≥ 98.0%Cor e Forma:White to off-white crystalline powderPeso molecular:282.33Artemisinin (Standard)
CAS:Artemisinin (Standard) is a reference standard for research and analysis in studies involving Artemisinin. Artemisinin (Qinghaosu) is a natural product, a sesquiterpene lactone, derived from Artemisia annua. Artemisinin has anti-malarial activity, as well as neuroprotective and anti-tumor activity.Fórmula:C15H22O5Cor e Forma:SolidPeso molecular:282.33Artemisinin
CAS:(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-Trimethyloctahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-oneFórmula:C15H22O5Pureza:97%Peso molecular:282.33Artemisinin
CAS:ArtemisininFórmula:C15H22O5Pureza:97%Cor e Forma:White Solid-CrystalsPeso molecular:282.33218Artemisinin
CAS:Artemisinin is a sesquiterpene lactone, which is derived from the plant Artemisia annua, commonly known as sweet wormwood. This compound is isolated through a series of extraction and purification processes from the plant's leaves and flowers. Artemisinin exerts its pharmacological effect through a novel mode of action that involves endoperoxide bridges, which interact with intracellular iron to generate free radicals. These reactive species subsequently damage vital biomolecules within Plasmodium parasites, effectively inhibiting their ability to thrive and reproduce.Fórmula:C15H22O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:282.33 g/mol
![(1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]h…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00IBB0.jpg&w=3840&q=75)
