CAS 667905-37-5

Fórmula: C18H13ClF3N5O

InChI: InChI=1S/C18H13ClF3N5O/c19-12-2-1-3-13(8-12)26-17-25-10-14(15(27-17)18(20,21)22)16(28)24-9-11-4-6-23-7-5-11/h1-8,10H,9H2,(H,24,28)(H,25,26,27)

Chave InChI: HLCPJLIYGNWTAI-UHFFFAOYSA-N

SMILES: C1=CC(=CC(=C1)Cl)NC2=NC=C(C(=N2)C(F)(F)F)C(=O)NCC3=CC=NC=C3

GW 833972A

CAS: 667905-37-5

A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).

Fórmula: C₁₈H₁₃ClF₃N₅O

Pureza: Min. 95%

Cor e Forma: White To Off-White Solid

Peso molecular: 407.78 g/mol

Ref: 3D-FG76601

GW-833972A free base

CAS: 667905-37-5

GW833972 is a CB2 agonist that inhibits depolarization and cough in guinea pigs but not plasma extravasation; effects are CB2 antagonist reversible.

Fórmula: C₁₈H₁₃ClF₃N₅O

Cor e Forma: Solid

Peso molecular: 407.78

Ref: TM-T68904