CAS 6893-02-3

Triiodotironina

Descrição:

Triiodotironina, comumente referido como T3, é um hormônio tireoidiano que desempenha um papel crucial na regulação do metabolismo, crescimento e desenvolvimento no corpo. É sintetizado a partir da tiroxina (T4) e contém três átomos de iodo, que são essenciais para sua atividade biológica. T3 é uma molécula lipofílica, permitindo que atravesse facilmente as membranas celulares e se ligue a receptores nucleares, influenciando a expressão gênica e os processos metabólicos. O hormônio é produzido principalmente na glândula tireoide e está envolvido em várias funções fisiológicas, incluindo a regulação da frequência cardíaca, temperatura corporal e gasto energético. T3 é tipicamente medido em ambientes clínicos para avaliar a função tireoidiana e diagnosticar distúrbios como hipotireoidismo ou hipertireoidismo. Sua estrutura química inclui um anel fenólico e um grupo amino, contribuindo para sua atividade biológica. Devido aos seus efeitos potentes, T3 também é utilizado terapeuticamente em certas condições médicas, mas sua administração deve ser cuidadosamente monitorada para evitar potenciais efeitos colaterais associados ao desequilíbrio hormonal da tireoide.

Fórmula: C₁₅H₁₂I₃NO₄

InChI: InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

Chave InChI: InChIKey=AUYYCJSJGJYCDS-LBPRGKRZSA-N

SMILES: O(C1=C(I)C=C(C[C@@H](C(O)=O)N)C=C1I)C2=CC(I)=C(O)C=C2

Sinónimos:

• (2S)-2-Azaniumyl-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
• (S)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoicacid
• 3',5-Triiodo-L-Thyronin
• 3,3',5-Triiodothyronine
• 3,3′,5-Triiodo-<span class="text-smallcaps">L</span>-thyronine
• 3,3′,5-Triiodothyronine
• 3,5,3'-Triiodothyronine
• 4-(3-Iodo-4-Hydroxyphenoxy)-3,5-Diiodophenylalanine
• 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylalanine
• 5-Diiodophenyl)-3-(4-(4-Hydroxy-3-Iodophenoxy)-L-Alanin
• <span class="text-smallcaps">L</span>-3,3′,5-Triiodothyronine
• <span class="text-smallcaps">L</span>-Liothyronine
• <span class="text-smallcaps">L</span>-T₃
• <span class="text-smallcaps">L</span>-Triiodothyronine
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, <span class="text-smallcaps">L</span>-
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, L-
• Cyronine
• Cytomel
• L-3,3',5-Triiodothyronine
• L-3,3,5-Triiodothyronine, Free Acid
• L-3-(4-(4-Hydroxy-3-Iodophenoxy)-3,5-Diiodophenyl)Alanine
• L-Liothyronine
• L-T3
• L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• L-triiodothyronine
• Liothyronin
• Liothyronine
• Liotironina
• Nsc 80203
• O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-<span class="text-smallcaps">L</span>-tyrosine
• O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
• O-(4-hydroxyphenyl)-2,3,5-triiodotyrosine
• T3
• T3 (Hormone)
• T3 (amino acid)
• T₃
• T₃ (Hormone)
• T₃ (amino acid)
• Thyronine, 3,3',5-triiodo-, L-
• Thyronine, 3,3′,5-triiodo-, <span class="text-smallcaps">L</span>-
• Tresitope
• Triiodo-<span class="text-smallcaps">L</span>-thyronine
• Triiodo-L-thyronine
• Triiodothyronine

3,3',5-Triiodo-L-thyronine

CAS: 6893-02-3

Fórmula: C₁₅H₁₂I₃NO₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow to Light orange powder to crystal

Peso molecular: 650.98

Ref: 3B-T0453

3,3',5-Triiodo-L-thyronine, 95%

CAS: 6893-02-3

Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3', 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3', 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and

Fórmula: C₁₅H₁₂I₃NO₄

Pureza: 95%

Cor e Forma: White to cream to yellow to pale brown, Powder or crystalline powder or solid

Peso molecular: 650.98

Ref: 02-H34068

Liothyronine

CAS: 6893-02-3

Amino-acid derivatives

Fórmula: C₁₅H₁₂I₃NO₄

Cor e Forma: White Cream Powder

Peso molecular: 650.79005

Ref: 45-1368008

3,3',5-Triiodo-L-Thyronine

CAS: 6893-02-3

3,3',5-Triiodo-L-Thyronine

Fórmula: C₁₅H₁₂I₃NO₄

Pureza: 97%

Peso molecular: 650.97

Ref: 54-OR1010733

3,3',5-Triiodo-L-thyronine

CAS: 6893-02-3

Fórmula: C₁₅H₁₂I₃NO₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 650.9735

Ref: IN-DA0032GT

Liothyronine

CAS: 6893-02-3

Fórmula: C₁₅H₁₂I₃NO₄

Cor e Forma: White To Off-White Solid

Peso molecular: 650.98

Ref: 4Z-T-423

3,3'',5-Triiodo-L-thyronine

CAS: 6893-02-3

Fórmula: C₁₅H₁₂I₃NO₄

Pureza: ≥ 98.0%

Cor e Forma: White to off-white or faint yellow powder

Peso molecular: 650.97

Ref: 7W-GE2741

Liothyronine

CAS: 6893-02-3

Liothyronine

Fórmula: C₁₅H₁₂I₃NO₄

Pureza: ≥98%

Peso molecular: 650.97

Ref: 54-BUP15946

Liothyronine (Standard)

CAS: 6893-02-3

Liothyronine (Standard) is a reference standard for research and analysis in studies involving Liothyronine. Liothyronine (Tresitope) is a synthetic and highly active thyroid hormone that acts as an effective agonist of TRα and TRβ (Ki = 2.33 nM for both hTRα and hTRβ). It activates the TRβ1 receptor, promotes the metabolism of carbohydrates, proteins, and fats, accelerates the oxidative processes in tissue cells, maintains basal metabolic rate, and supports normal growth and development. Liothyronine can be used to induce hyperthyroidism models.

Fórmula: C₁₅H₁₂I₃NO₄

Peso molecular: 650.97

Ref: TM-TMSM-3271

Liothyronine

CAS: 6893-02-3

Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.

Fórmula: C₁₅H₁₂I₃NO₄

Pureza: 98.61% - 99.33%

Cor e Forma: Crystals Solid

Peso molecular: 650.97

Ref: TM-T1653

Liothyronine-13C9-15N

CAS: 6893-02-3

Fórmula: C₆₁₃C₉H₁₂I₃₁₅NO₄

Peso molecular: 348.36

Ref: 4Z-T-4228

Liothyronine

CAS: 6893-02-3

Fórmula: C₁₅H₁₂I₃NO₄

Peso molecular: 650.98

Ref: ST-EA-CP-L45000

3,3’,5-Triiodo-L-thyronine

Produto Controlado

CAS: 6893-02-3

Fórmula: C₁₅H₁₂I₃NO₄

Cor e Forma: Neat

Peso molecular: 650.97

Ref: TR-T795380

3,3',5-Triiodo-L-thyronine

CAS: 6893-02-3

Triiodothyronine (T3) is a thyroid hormone that has a high affinity for the thyrotropin receptor. It regulates the metabolic rate, cell specific transcriptional regulation, and transcriptional regulation of genes involved in fatty acid synthesis. T3 is synthesized from the amino acid tyrosine through a series of reactions catalyzed by enzymes such as tyrosine hydroxylase, thyroperoxidase, and type 2 iodothyronine deiodinase. The enzyme thyroid peroxidase converts inactive T3 to the active form of T3 (triiodothyronine). In addition, triiodothyronine can be converted to reverse T3 (rT3), which is inactive. Triiodothyronine has an optimal ph of 7.4-8.0 and an optimum igf-i concentration of 100 ng/ml, where it can stimulate growth hormone release from the anterior pituitary gland.

Fórmula: C₁₅H₁₂I₃NO₄

Pureza: Min. 95 Area-%

Cor e Forma: Off-White Powder

Peso molecular: 650.97 g/mol

Ref: 3D-FT28506

3,3,5-Triiodo-L-Thyronine extrapure, 95%

CAS: 6893-02-3

Fórmula: C₁₅H₁₂I₃NO₄

Pureza: min. 95%

Cor e Forma: White to off-white, Powder

Peso molecular: 650.98

Ref: SR-35241

Liothyronine

CAS: 6893-02-3

Pureza: 98%

Peso molecular: 650.9769897

Ref: 10-F787598