CAS 6990-06-3

Ácido fusídico

Descrição:

Ácido fusídico é um antibiótico esteroidal derivado principalmente do fungo Fusidium coccineum. É caracterizado pela sua capacidade de inibir a síntese de proteínas bacterianas, tornando-o eficaz contra uma variedade de bactérias Gram-positivas, incluindo Staphylococcus aureus. Ácido fusídico é frequentemente utilizado em formulações tópicas para tratar infecções cutâneas, particularmente aquelas causadas por cepas resistentes. O composto é conhecido por sua baixa solubilidade em água, o que influencia sua formulação e métodos de entrega. Tem um perfil de toxicidade relativamente baixo, mas seu uso pode levar à resistência se não for administrado adequadamente. Ácido fusídico está tipicamente disponível em várias formas, incluindo cremes, pomadas e colírios, e às vezes é combinado com outros antibióticos para aumentar sua eficácia. Seu mecanismo de ação envolve a ligação ao fator de elongação G (EF-G) nas bactérias, impedindo assim a etapa de translocação durante a síntese de proteínas. No geral, Ácido fusídico é um agente valioso no tratamento de infecções localizadas, particularmente em aplicações dermatológicas.

Fórmula: C₃₁H₄₈O₆

InChI: InChI=1/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/b26-20+/t18-,21-,22-,23+,24+,25-,27?,29-,30-,31-/m0/s1

Chave InChI: InChIKey=IECPWNUMDGFDKC-MZJAQBGESA-N

SMILES: C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(C[C@@H](O)[C@]1([C@]4(C)[C@@](CC2)([C@H](C)[C@H](O)CC4)[H])[H])[H]

Sinónimos:

• (2E)-2-[(3alpha,4alpha,5alpha,8alpha,9xi,11alpha,13alpha,14beta,16beta,17E)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• (2Z)-2-[(3alpha,4alpha,5alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• 16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, 16-acetate, (Z)-
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-
• Acide Fusidique
• Acido Fusidico
• Flucidin
• Foban
• Fucithalmic
• Fugen
• Fusidate Acid
• Fusidic Acid
• Fusidine
• Fusidinic acid
• Fusidinsaure
• Nsc 56192
• Optifucin
• Phudicin
• Ramycin
• Sq 16603
• Usidin
• (3alpha,4alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-29-Nordammara-17(20),24-dien-21-oic acid
• 4-alpha,8-alpha,9-beta,11-alpha,13-alpha,14-beta,16-beta,17z)-ph
• FUSIDIC ACID IP
• (4S,8α,9β,13α,14β,17Z)-16β-Acetoxy-3α,11α-dihydroxy-29-nor-5α-dammara-17(20),24-dien-21-oic acid
• (8α,9β,13α,14β,Z)-16β-Acetyloxy-3α,11α-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• sq16603
• (3ALPHA,4ALPHA,8ALPHA,9BETA,11ALPHA,13ALPHA,14BETA,16BETA,17Z)-16-(ACETYLOXY)-3,11-DIHYDROXY-29-NORDAMMARA-17(20),24-DIEN-21-OIC ACID
• (3a,4a,8a,9,11a,13a,147,167,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic Acid
• 24-dien-21-oicacid,16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20(3-al
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3.alpha.,4.alpha.,8.alpha.,9.beta.,11.alpha.,13.alpha.,14.beta.,16.beta.,17Z)-

Fusidic acid; Fucidin; Ramycin; NSC 56192; NSC-5619-2; SQ 16603; ZN-6; Fusidinic acid

CAS: 6990-06-3

Fórmula: C₃₁H₄₈O₆

Pureza: 85.66%

Cor e Forma: Brownish oily solid

Peso molecular: 516.0

Ref: 8R-AD0023

FUSIDIC ACID CRS

CAS: 6990-06-3

FUSIDIC ACID CRS

Fórmula: C₃₁H₄₈O₆

Cor e Forma: Added Modified

Peso molecular: 516.7092

Ref: 41-Y0001411

FUSIDIC ACID FOR PEAK IDENTIFICATION CRS

CAS: 6990-06-3

FUSIDIC ACID FOR PEAK IDENTIFICATION CRS

Fórmula: C₃₁H₄₈O₆

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 516.7092

Ref: 41-Y0001394

Fusidic acid

CAS: 6990-06-3

Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.

Fórmula: C₃₁H₄₈O₆

Pureza: 98.68% - 99.53%

Cor e Forma: White Solid

Peso molecular: 516.71

Ref: TM-T1160

Fusidic acid

CAS: 6990-06-3

Fusidic acid

Fórmula: C₃₁H₄₈O₆

Pureza: ≥98%

Peso molecular: 516.71

Ref: 54-BUP16640

(3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid

CAS: 6990-06-3

Fórmula: C₃₁H₄₈O₆

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 516.7092

Ref: IN-DA003ACO

Fusidic Acid

CAS: 6990-06-3

Fórmula: C₃₁H₄₈O₆

Cor e Forma: White To Off-White Solid

Peso molecular: 516.72

Ref: 4Z-F-281

Fusidic acid

CAS: 6990-06-3

Fórmula: C₃₁H₄₈O₆·xH₂O

Pureza: 98.0 - 101.0 % (dried basis)

Cor e Forma: White or almost white crystalline powder

Peso molecular: 516.71 (anhydrous)

Ref: 7W-GA1848

Fusidic Acid (Standard)

CAS: 6990-06-3

Fusidic Acid (Standard) is the standard substance of Fusidic Acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.

Fórmula: C₃₁H₄₈O₆

Peso molecular: 516.71

Ref: TM-TMSM-1248

Fusidic acid

Produto Controlado

CAS: 6990-06-3

Fórmula: C₃₁H₄₈O₆

Cor e Forma: Neat

Peso molecular: 516.71

Ref: 04-C13989500

Fusidic Acid

CAS: 6990-06-3

Fórmula: C₃₁H₄₈O₆

Pureza: >97.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 516.72

Ref: 3B-F1007

Fusidic acid, free acid

CAS: 6990-06-3

Fusidic acid, free acid

Fórmula: C₃₁H₄₈O₆

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 516.70921

Ref: 54-BIF6400

Fusidic Acid

CAS: 6990-06-3

Fórmula: C₃₁H₄₈O₆

Peso molecular: 516.72

Ref: ST-EA-CP-F45016

Fusidic Acid-d6

Produto Controlado

CAS: 6990-06-3

Applications Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
References Collignon, P., et al.: Int. J. Antimicrob. Agents, 12, S45 (1999), Di Marco, R., et al.: J. Autoimmun., 13, 187 (1999), Price, C.T., et al.: J. Antimicrob., Chemother., 44, 57 (1999),

Fórmula: C₃₁H₄₂D₆O₆

Cor e Forma: Neat

Peso molecular: 522.71

Ref: TR-F865502

FUSIDIC ACID

CAS: 6990-06-3

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 516.718994140625

Ref: 10-F794556

Fusidic Acid

CAS: 6990-06-3

Stability Hygroscopic
Applications Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Dyes and metabolites.
References Collignon, P., et al.: Int. J. Antimicrob. Agents, 12, S45 (1999), Di Marco, R., et al.: J. Autoimmun., 13, 187 (1999), Price, C.T., et al.: J. Antimicrob., Chemother., 44, 57 (1999),

Fórmula: C₃₁H₄₈O₆

Cor e Forma: Neat

Peso molecular: 516.71

Ref: TR-F865500

Fusidic acid

CAS: 6990-06-3

Inhibitor of protein synthesis; steroid antibiotic

Fórmula: C₃₁H₄₈O₆

Pureza: Min. 95 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 516.71 g/mol

Ref: 3D-AF23629

Fusidine

CAS: 6990-06-3

(Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-3,11-dihydroxy-4,8,10,14-tetramethyldodecahydro-1H-cyclopenta[a]phenanthren-17(2H,10H,14H)-ylidene)-6-methylhept-5-enoic acid

Fórmula: C₃₁H₄₈O₆

Pureza: 97%

Peso molecular: 516.71

Ref: IN-DG105687