CAS 701226-08-6

(4,5-Diidro-3,5-difenil-1H-pirazol-1-il)-2-furanil-metano

Fórmula: C₂₀H₁₆N₂O₂

InChI: InChI=1S/C20H16N2O2/c23-20(19-12-7-13-24-19)22-18(16-10-5-2-6-11-16)14-17(21-22)15-8-3-1-4-9-15/h1-13,18H,14H2

Chave InChI: VEIXLXIVAMCBLZ-UHFFFAOYSA-N

SMILES: C1C(N(N=C1C2=CC=CC=C2)C(=O)C3=CC=CO3)C4=CC=CC=C4

Sinónimos:

• Methanone, (4,5-dihydro-3,5-diphenyl-1H-pyrazol-1-yl)-2-furanyl-
• (3,5-diphenyl-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone
• Rhodblock 1a
• (4,5-Dihydro-3,5-diphenyl-1H-pyrazol-1-yl)-2-furanyl-methanone

Rhodblock 1a

CAS: 701226-08-6

Rhodblock 1a is an inhibitor of the Rho kinase signaling pathway, which disrupts the localization and function of proteins within the Rho pathway. This interference hinders the proper formation of the cleavage furrow during cell division, leading to some cells either failing to form the cleavage furrow or forming a ruptured furrow, resulting in binucleated cells. Rhodblock 1a can be utilized for investigating cell division mechanisms and holds potential for research into cardiovascular diseases and cancer.

Fórmula: C₂₀H₁₆N₂O₂

Cor e Forma: Solid

Peso molecular: 316.3532

Ref: TM-T206882