CAS 716354-04-0

AWXQYTLSBPWDMJ-KUMHGWDASA-N

Fórmula: C₃₆H₄₀ClF₂N₅O₃S

InChI: InChI=1S/C36H40ClF2N5O3S/c1-23-41-32-8-3-4-9-33(32)44(23)28-19-26-10-11-27(20-28)43(26)17-14-36(24-6-5-7-25(38)18-24)12-15-42(16-13-36)35(45)29-21-34(48(46,47)40-2)31(39)22-30(29)37/h3-9,18,21-22,26-28,40H,10-17,19-20H2,1-2H3/t26-,27+,28?

Chave InChI: AWXQYTLSBPWDMJ-FITHBNAOSA-N

SMILES: CC1=NC2=CC=CC=C2N1C3C[C@H]4CC[C@@H](C3)N4CCC5(CCN(CC5)C(=O)C6=CC(=C(C=C6Cl)F)S(=O)(=O)NC)C7=CC(=CC=C7)F

Sinónimos:

• Benzenesulfonamide, 4-chloro-2-fluoro-5-[[4-(3-fluorophenyl)-4-[2-[(3-endo)-3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl]-1-piperidinyl]carbonyl]-N-methyl-
• AWXQYTLSBPWDMJ-KUMHGWDASA-N

GSK163929

CAS: 716354-04-0

GSK163929 (compound 122) is an orally active CCR5 antagonist with anti-HIV properties and demonstrates low inhibitory potency against hEGR. Administered at a dosage of 2000 mg/kg/day (i.v., 7 d), it shows no adverse effects in rats, and at 250 mg/kg/day (i.v., 7 d), it is similarly non-toxic in dogs.

Fórmula: C₃₆H₄₀ClF₂N₅O₃S

Cor e Forma: Solid

Peso molecular: 696.25

Ref: TM-T203363