CAS 7177-50-6
:Nafcilina sódica monoidratada
Descrição:
Nafcilina sódica monoidratada é um antibiótico penicilínico semissintético, utilizado principalmente para tratar infecções causadas por estafilococos produtores de penicilinase. É caracterizado por sua capacidade de resistir à degradação por certas beta-lactamases, tornando-o eficaz contra cepas bacterianas específicas. O composto aparece como um pó cristalino branco a off-white e é solúvel em água, o que facilita sua administração por injeção. Sua estrutura molecular inclui um anel beta-lactâmico, um anel de tiazolidina e um íon de sódio, contribuindo para suas propriedades antibacterianas. Nafcilina sódica monoidratada é tipicamente administrado por via intravenosa ou intramuscular, e sua farmacocinética envolve rápida distribuição nos tecidos do corpo, com uma meia-vida relativamente curta. Os efeitos colaterais comuns podem incluir reações alérgicas, distúrbios gastrointestinais e potencial nefrotoxicidade. Assim como outros antibióticos, é essencial usar Nafcilina sódica monoidratada de forma judiciosa para prevenir o desenvolvimento de resistência a antibióticos. No geral, continua sendo uma opção crítica no tratamento de certas infecções bacterianas, particularmente aquelas causadas por cepas resistentes.
Fórmula:C21H23N2NaO6S
InChI:InChI=1/C21H22N2O5S.Na.H2O/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23;;/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27);;1H2/q;+1;/p-1/t15-,16+,19-;;/m1../s1
Chave InChI:InChIKey=RKBDQTFFBRQMPN-KMFBOIRUSA-N
SMILES:C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(=O)C=3C4=C(C=CC3OCC)C=CC=C4)C2=O)(SC1(C)C)[H].[Na].O
Sinónimos:- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S-(2alpha,5alpha,6beta))
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S,5R,6R)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, [2S-(2α,5α,6β)]-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt, hydrate (1:1:1), (2S,5R,6R)-
- Monosodium (2S,5R,6R)-6-(2-ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate monohydrate
- Nafcil
- Nafcillin natrium-1-wasser
- Nafcillin sodium salt monohydrate
- Sodium 6-(2-ethoxy-1-naphthamido)penicillanate monohydrate
- Sodium nafcillin monohydrate
- Unii-49G3001Bck
- Wy 3277
- sodium (2S,5R,6R)-6-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
- Nafcillin monohydrate sodium salt
- NAFCILLINSODIUMSTERILE
- Sodium (2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
- nafcillin sodium
- Ver mais sinónimos
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100
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50
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90
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95
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100
Foram encontrados 10 produtos.
Nafcillin Sodium
CAS:Penicillins and their derivatives with a penicillanic acid structure and salts thereof, nesoiFórmula:C21H21N2NaO5S·H2OCor e Forma:White Light Yellow Crystalline PowderPeso molecular:454.11745Nafcillin sodium monohydrate
CAS:Nafcillin sodium monohydrate (CL 8491) is a semi-synthetic naphthalene, nafcillin inhibits bacterial wall synthesis by a mechanism similar to penicillin.Fórmula:C21H21N2O5SNa·H2OPureza:96.62%Cor e Forma:White PowderPeso molecular:454.47(2S,5R,6R)-6-[[(2-Ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium hydrate
CAS:Fórmula:C21H23N2NaO6SPureza:98%Cor e Forma:SolidPeso molecular:454.4719Nafcillin sodium monohydrate
CAS:Nafcillin sodium monohydrateFórmula:C21H21N2O5SNa·H2OPureza:≥90%Cor e Forma:SolidPeso molecular:454.47Nafcillin sodium salt monohydrate
CAS:Nafcillin sodium salt monohydratePureza:98%(Contain 2-3% ethyl acetate)Peso molecular:454.47g/molNafcillin sodium monohydrate 100 µg/mL in Acetonitrile
CAS:Fórmula:C21H21N2O5S·Na·H2OCor e Forma:Single SolutionPeso molecular:454.47Nafcillin sodium salt monohydrate
CAS:Fórmula:C21H21N2O5SNa·H2OPureza:≥ 98.5% (anhydrous basis)Cor e Forma:White to yellow crystalline powder or crystalsPeso molecular:454.47Sodium Nafcillin Monohydrate
CAS:Applications Sodium Nafcillin Monohydrate is used as an antibiotic, used in the treatment, used in the treatment of gram-positive bacteria.
References Taboada, P. et al.: Langmuir. 16, 3175 (2000);Fórmula:C21H21N2O5S·Na·H2OCor e Forma:NeatPeso molecular:454.47Nafcilllin sodium monohydrate
CAS:Nafcillin sodium monohydrate is a beta-lactam antibiotic, which is derived from the penicillin class of antimicrobials. It is specifically a semi-synthetic penicillin and is commonly sourced through chemical synthesis to enhance its stability and spectrum of activity. Nafcillin primarily exerts its bactericidal effects by inhibiting bacterial cell wall synthesis. It achieves this through its strong affinity for penicillin-binding proteins (PBPs), which are essential for maintaining the bacterial cell wall structure. By disrupting the formation of peptidoglycan cross-links, nafcillin effectively weakens the bacterial cell wall, leading to cell lysis and death, especially in gram-positive bacteria such as Staphylococcus aureus, including methicillin-sensitive strains (MSSA).Fórmula:C21H21N2O5SNa·H2OPureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:454.47 g/mol
![(2S,5R,6R)-6-[[(2-Ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2…](https://static.cymitquimica.com/products/IN/thumb/DA0062G3.jpg)
