CAS 73231-34-2
:Florfenicol
Descrição:
Florfenicol é um antibiótico sintético pertencente à classe dos fenicóis, utilizado principalmente na medicina veterinária para o tratamento de infecções bacterianas em animais. É eficaz contra um amplo espectro de bactérias Gram-positivas e Gram-negativas, tornando-se um agente terapêutico valioso. Florfenicol atua inibindo a síntese de proteínas bacterianas, direcionando-se especificamente à subunidade ribossomal 50S, o que interrompe a produção de proteínas essenciais necessárias para o crescimento e reprodução bacteriana. A substância é caracterizada por sua toxicidade relativamente baixa em animais em comparação com outros antibióticos, o que permite seu uso em animais de produção de alimentos sob condições regulamentadas. Florfenicol é tipicamente administrado por injeção ou em formulações de ração, e sua farmacocinética indica boa penetração nos tecidos, o que é benéfico para o tratamento de infecções sistêmicas. No entanto, seu uso está sujeito a regulamentações rigorosas devido a preocupações sobre resistência a antibióticos e possíveis resíduos em produtos alimentícios. No geral, Florfenicol representa uma ferramenta importante na medicina veterinária, equilibrando eficácia contra infecções bacterianas com considerações de segurança e conformidade regulatória.
Fórmula:C12H14Cl2FNO4S
InChI:InChI=1/C12H14Cl2FNO2S/c1-19-8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)
Chave InChI:InChIKey=AYIRNRDRBQJXIF-NXEZZACHSA-N
SMILES:[C@@H]([C@H](NC(C(Cl)Cl)=O)CF)(O)C1=CC=C(S(C)(=O)=O)C=C1
Sinónimos:- 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
- 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
- 2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
- 2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide
- Acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-
- Acetamide, 2,2-dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,S*)]-
- Aquafen
- Aquaflor
- Flofenicol
- Flonicol
- Florfeniol
- Florgane
- Floron
- Nuflor
- Sch 25298
- Selectan
- Topazone
- Florfenicol
- [R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
- Fluorothiamphenicol
- [r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
- Sch-25298, Aquafen
- (r-(r*,s*))-methyleste
- 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
- 2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
- Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
- FLUPROFEN
- Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
- 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid
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Foram encontrados 20 produtos.
Florfenicol
CAS:Fórmula:C12H14Cl2FNO4SPureza:>98.0%(HPLC)(N)Cor e Forma:White to Light yellow powder to crystalPeso molecular:358.21Florfenicol, 98%
CAS:A bacteriostatic antibiotic similar to chloramphenicol which inhibits bacterial protein synthesis This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar prFórmula:C12H14Cl2FNO4SPureza:98%Cor e Forma:White to pale cream, Powder or crystalline powderPeso molecular:358.21Acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-
CAS:Fórmula:C12H14Cl2FNO4SPureza:%Cor e Forma:SolidPeso molecular:358.2133Ref: IN-DA00ICDO
5g23,00€25g28,00€50g49,00€75g57,00€100g64,00€200g95,00€300g112,00€400g146,00€500g167,00€Florfenicol
CAS:Florfenicol treats bovine respiratory disease and foot rot in cattle, and catfish enteric septicemia.Fórmula:C12H14Cl2FNO4SPureza:99.22% - 99.33%Cor e Forma:White SolidPeso molecular:358.21Florfenicol
CAS:Fórmula:C12H14Cl2FNO4SPureza:≥ 98.0% (dried basis)Cor e Forma:White to off-white powderPeso molecular:358.21Florfenicol
CAS:Applications Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.
References Kim, E and Aoki, T.: Microbiol. Immunol., 40, 665, (1996), Keyes, K.: Antimicrob. Agents Chemother., 44, 421 (2000)Fórmula:C12H14Cl2FNO4SCor e Forma:NeatPeso molecular:358.21Florfenicol
CAS:Florfenicol is a broad-spectrum antibiotic that belongs to the group of florfenicol. It is used in veterinary medicine to treat bacterial infections in animals, including those caused by salmonella, streptococcus, and mycoplasma. Florfenicol has been shown to have an inhibitory effect on the growth of tetracycline-resistant bacteria. Florfenicol binds reversibly to the 23S ribosomal RNA in the 50S subunit of bacteria and inhibits protein synthesis. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme ribosome that is required for translation, inhibiting protein synthesis and cell division. The rate constant for this reaction has been determined using a combination of analytical methods, including chromatographic analysis and colloidal gold electrophoresis. Florfenicol also has anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.Fórmula:C12H14Cl2FNO4SPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:358.21 g/molFlorfenicol - Bio-X ™
CAS:Florfenicol is a broad-spectrum antibiotic used for the treatment of various bacteria infections. This drug is used in veterinary medicine and to treat animals with those infections. This drug works by inhibiting bacteria synthesis. It is a fluorinated synthetic analog of thiamphenicol.Fórmula:C12H14Cl2FNO4SPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:358.21 g/mol
