CAS 751-03-1

Obacunona

Descrição:

Obacunona é um composto natural classificado como limonoide, derivado principalmente das sementes do fruto do gênero Citrus, particularmente da espécie Citrus Obacunona. É caracterizado por sua complexa estrutura tetracíclica, que inclui um sistema de anéis fundidos que contribui para sua atividade biológica. Obacunona exibe uma variedade de propriedades farmacológicas, incluindo efeitos anti-inflamatórios, anticancerígenos e antimicrobianos, tornando-se um assunto de interesse na química medicinal e na pesquisa de produtos naturais. O composto é tipicamente encontrado em baixas concentrações em frutas cítricas, e sua extração e purificação podem ser desafiadoras devido à sua complexidade estrutural. Em termos de propriedades físicas, Obacunona é geralmente um sólido incolorido a amarelo pálido com um odor característico. Sua solubilidade varia, sendo mais solúvel em solventes orgânicos do que em água. O estudo de Obacunona continua a revelar suas potenciais aplicações em produtos farmacêuticos e alimentos funcionais, destacando a importância dos compostos naturais na descoberta e desenvolvimento de medicamentos.

Fórmula: C₂₆H₃₀O₇

InChI: InChI=1S/C26H30O7/c1-22(2)16-12-17(27)25(5)15(23(16,3)9-7-18(28)32-22)6-10-24(4)19(14-8-11-30-13-14)31-21(29)20-26(24,25)33-20/h7-9,11,13,15-16,19-20H,6,10,12H2,1-5H3/t15-,16+,19+,20-,23-,24+,25+,26-/m1/s1

Chave InChI: InChIKey=MAYJEFRPIKEYBL-OASIGRBWSA-N

SMILES: C[C@]12[C@]34[C@](O3)(C(=O)O[C@H]([C@]4(C)CC[C@@]1([C@]5(C)[C@@](CC2=O)(C(C)(C)OC(=O)C=C5)[H])[H])C=6C=COC6)[H]

Sinónimos:

• (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione
• (5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-5b,6,7,7a,8,11b,13,13a-octahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10,12(1H,5aH,10aH)-trione
• (5aR,7aS,8R,10aS,11aR,11bR)-8-(furan-3-yl)-12,12-dihydroxy-1,1,5a,7a,11b-pentamethyl-5a,5b,6,7,7a,8,11b,12,13,13a-decahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10(1H,10aH)-dione
• 14,15:21,23-Diepoxy-4,4,8-trimethyl-A,<span class="text-smallcaps">D</span>-dihomo-24-nor-4,17-dioxachola-1,20,22-triene-3,7,16-trione
• Ai3-37934
• Ccris 8657
• Obacunoic acid 3,4-lactone
• Obacunoic acid, eta-lactone
• Obacunoic acid, ε-lactone
• Obacunon
• Obakunone
• Oxireno(4,4a)-2-benzopyrano(6,5-g)(2)benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11aR,11bR,11bR,13aS)-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, [1S-(1α,3aα,4aS*,4bβ,6aα,11aβ,11bα,13aα)]-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aαH,4bH,6H)-trione, 1α-(3-furyl)-1,6aα,7,11a,11bα,12,13,13a-octahydro-4bβ,7,7,11aβ,13aα-pentamethyl-
• Tricoccin S₃
• [1S-(1α,3aα,4aS*,4bβ,6aα,11aβ,11bα,13aα)]-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Pureza: >98.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 454.52

Ref: 3B-O0506

Obacunone

CAS: 751-03-1

Obacunone

Fórmula: C₂₆H₃₀O₇

Pureza: 98%

Peso molecular: 454.51

Ref: 54-OR1023060

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.52

Ref: 7W-GY8065

Obacunone

CAS: 751-03-1

Obacunone

Fórmula: C₂₆H₃₀O₇

Pureza: 99.5%

Cor e Forma: Solid

Peso molecular: 454.51

Ref: 54-BUP10739

(1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 454.5122

Ref: IN-DA00G2A6

Obacunone (Standard)

CAS: 751-03-1

Obacunone (Standard) is a reference standard for research and analysis in studies involving Obacunone. Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.

Fórmula: C₂₆H₃₀O₇

Cor e Forma: Solid

Peso molecular: 454.5122

Ref: TM-TMSM-1938

Obacunone

CAS: 751-03-1

Obacunone is a novel activator of Nrf2, which exhibits anti-cancer, anti-inflammatory, antivirulence, insecticidal, anti-proliferative and anti-aromatase activities. Obacunone stimulates muscle hypertrophy and prevents obesity and hyperglycemia, and that these beneficial effects are likely to be mediated through the activation of TGR5 and inhibition of PPARγ transcriptional activity. Obacunone significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM, and it also inhibits the p38 MAPK signaling pathway.

Fórmula: C₂₆H₃₀O₇

Pureza: 95%~99%

Peso molecular: 454.519

Ref: BP-BP1018

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.52

Ref: 4Z-O-086001

Obacunone

CAS: 751-03-1

Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.

Fórmula: C₂₆H₃₀O₇

Pureza: 98% - ≥95%

Cor e Forma: White Powder

Peso molecular: 454.5122

Ref: TM-T3390

Obacunone

CAS: 751-03-1

(1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione

Fórmula: C₂₆H₃₀O₇

Pureza: 98%

Peso molecular: 454.51

Ref: IN-DG299914

Obacunone

CAS: 751-03-1

Lactone

Fórmula: C₂₆H₃₀O₇

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 454.52

Ref: 5G-80509

Obacunone

CAS: 751-03-1

Obacunone is a naturally occurring limonoid, which is a type of triterpenoid compound. It is derived from the peels of citrus plants, particularly bitter and sweet oranges. Obacunone operates through several mechanisms, including inducing apoptosis, inhibiting cell proliferation, and modulating various signaling pathways. Its biological activity has garnered attention for its potential therapeutic benefits.

Fórmula: C₂₆H₃₀O₇

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 454.51 g/mol

Ref: 3D-FO65314

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.5

Ref: BE-RMT12350

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.5

Ref: BE-RMCO001000

OBACUNONE

CAS: 751-03-1

Pureza: 98%

Peso molecular: 454.5190125

Ref: 10-F795475

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.52

Ref: ST-EA-CP-O89000