CAS 775294-82-1

Fórmula: C24H27ClN2O4

InChI: InChI=1S/C24H27ClN2O4/c1-28-20-7-4-17(12-22(20)29-2)10-11-26-14-18-5-8-21(23(13-18)30-3)31-16-19-6-9-24(25)27-15-19/h4-9,12-13,15,26H,10-11,14,16H2,1-3H3

Chave InChI: XNPRQBVQOJZMMA-UHFFFAOYSA-N

SMILES: COC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC

SBE13

CAS: 775294-82-1

Fórmula: C₂₄H₂₇ClN₂O₄

Pureza: 98%

Peso molecular: 442.9352

Ref: IN-DA00G3RK

SBE13

CAS: 775294-82-1

SBE13 is a highly selective PLK1 inhibitor (IC₅₀=200 pM), a type II inhibitor with anti-tumor activity.

Fórmula: C₂₄H₂₇ClN₂O₄

Pureza: 99.59%

Cor e Forma: Solid

Peso molecular: 442.935

Ref: TM-T62591

SBE13

Produto Controlado

CAS: 775294-82-1

SBE13 is a molecule that inhibits the activity of the proteasome. It has been shown to have anti-cancer effects in vitro and in vivo, with an effective dose for inhibiting cancer cell proliferation at 1 μM. SBE13 binds to the 5-membered heteroaryl ring of plk1 and inhibits its kinase activity. This inhibition leads to decreased phosphorylation of glycogen synthase kinase 3β (GSK3β) and increased phosphorylation of cyclin D1, leading to a decrease in the rate of cell cycle progression. SBE13 also inhibits caco-2 cells proliferation, cervical cancer cells proliferation, and mcf-7 cell growth by interfering with cell cycle progression.

Fórmula: C₂₄H₂₇ClN₂O₄

Pureza: Min. 95%

Peso molecular: 442.9 g/mol

Ref: 3D-AGB29482