CAS 83883-10-7

Hidroxi-α-sanshool

Descrição:

Hidroxi-α-sanshool é um composto químico conhecido principalmente por sua presença na pimenta de Sichuan, uma especiaria que proporciona uma sensação única de dormência e formigamento na boca. Pertence à classe de compostos conhecidos como sanshools, que são caracterizados por suas estruturas alifáticas de cadeia longa. Hidroxi-α-sanshool é reconhecido por sua capacidade de ativar receptores sensoriais específicos, particularmente aqueles envolvidos na percepção de dor e temperatura, contribuindo para seus efeitos sensoriais distintos. O composto despertou interesse tanto em contextos culinários quanto medicinais devido aos seus potenciais benefícios à saúde, incluindo propriedades anti-inflamatórias e analgésicas. Sua estrutura molecular inclui grupos hidroxila, que aumentam sua solubilidade e reatividade. Hidroxi-α-sanshool é tipicamente estudado no contexto da química dos alimentos e farmacologia, onde suas atividades sensoriais e biológicas são exploradas. Assim como muitos compostos naturais, sua estabilidade e eficácia podem ser influenciadas por fatores como temperatura, pH e a presença de outras substâncias.

Fórmula: C₁₆H₂₅NO₂

InChI: InChI=1S/C16H25NO2/c1-4-5-6-7-8-9-10-11-12-13-15(18)17-14-16(2,3)19/h4-9,12-13,19H,10-11,14H2,1-3H3,(H,17,18)/b5-4+,7-6+,9-8-,13-12+

Chave InChI: InChIKey=LHFKHAVGGJJQFF-UEOYEZOQSA-N

SMILES: C(/C=C/CC/C=C\C=C\C=C\C)(NCC(C)(C)O)=O

Sinónimos:

• 2,6,8,10-Dodecatetraenamide, N-(2-hydroxy-2-methylpropyl)-, (E,E,Z,E)-
• Hydroxy-α-sanshool
• 2E,6Z,8E,10E-Dodecatetraenoic acid N-(2-hydroxy-2-methylpropyl)amide
• (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide
• 2,6,8,10-Dodecatetraenamide, N-(2-hydroxy-2-methylpropyl)-, (2E,6Z,8E,10E)-
• Hydroxy-alpha-Sanshool
• (2E,6Z,8E,10E)-N-(2-hydroxy-2-Methylpropyl)dodeca-2,6,8,10-tetra
• alpha-Hydroxy-Sanshool
• -N-(2-Hydroxy-2-methylpropyl)
• dodeca-2,6,8,10-tetraenamide
• （2E，6Z，8E，10E）-N-(2-hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide

(2E,6Z,8E,10E)-N-(2-Hydroxy-2-Methylpropyl)Dodeca-2,6,8,10-Tetraenamide

CAS: 83883-10-7

Fórmula: C₁₆H₂₅NO₂

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 263.3752

Ref: IN-DA008HUA

Hydroxy-α-sanshool

CAS: 83883-10-7

Hydroxy-α-sanshool

Fórmula: C₁₆H₂₅NO₂

Pureza: ≥95%

Cor e Forma: Solid

Peso molecular: 263.38

Ref: 54-BUP04863

Hydroxy-α-sanshool

CAS: 83883-10-7

Fórmula: C₁₆H₂₅NO₂

Pureza: ≥ 98.0%

Cor e Forma: White to beige solid

Peso molecular: 263.38

Ref: 7W-GY1523

Hydroxy-α-sanshool (Standard)

CAS: 83883-10-7

Hydroxy-α-sanshool (Standard) is a reference standard for research and analysis in studies involving Hydroxy-α-sanshool. Hydroxy-α-sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 μM).

Fórmula: C₁₆H₂₅NO₂

Cor e Forma: Solid

Peso molecular: 263.38

Ref: TM-TMSM-2630

Hydroxy-α-sanshool

CAS: 83883-10-7

Hydroxy-alpha-sanshool exerts antiobesity and hypolipidemic activities in HFD rats by reducing liver oxidative stress and thus could be considered as a potential candidate drug to cure or prevent obesity and hyperlipidemia. It also has analgesic properties, it activates TRPV1 and TRPA1 in sensory neurons.

Fórmula: C₁₆H₂₅NO₂

Pureza: 95%~99%

Peso molecular: 263.381

Ref: BP-BP4106

Hydroxy-α-sanshool

CAS: 83883-10-7

Hydroxy-α-sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 μM).

Fórmula: C₁₆H₂₅NO₂

Pureza: 97.51% - 99.47%

Cor e Forma: Yellow Solid

Peso molecular: 263.3752

Ref: TM-T8307

Hydroxy-α-sanshool

CAS: 83883-10-7

(2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide

Fórmula: C₁₆H₂₅NO₂

Pureza: 95%

Peso molecular: 263.38

Ref: IN-DG216962

Hydroxy-α-sanshool

CAS: 83883-10-7

Hydroxy-α-sanshool is a bioactive compound, which is a naturally occurring alkylamide. It is predominantly sourced from the fruit husks of the plant Zanthoxylum species, commonly known as Sichuan pepper. Hydroxy-α-sanshool is known for its unique mode of action, which involves the activation of specific ion channels in sensory neurons, notably the TRPV1 and TRPA1 channels. This activation results in a characteristic tingling and numbing sensation, commonly referred to as the "Sichuan pepper effect."

Fórmula: C₁₆H₂₅NO₂

Pureza: Min. 98 Area-%

Cor e Forma: Clear Viscous Liquid

Peso molecular: 263.38 g/mol

Ref: 3D-FH36486

Hydroxy-α-sanshool

CAS: 83883-10-7

Fórmula: C₁₆H₂₅NO₂

Peso molecular: 263.37

Ref: BE-RMT10562