CAS 841290-81-1

R406

CAS: 841290-81-1

Fórmula: C₂₈H₂₉FN₆O₈S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 628.6287

Ref: IN-DA00G3PP

6-((5-Fluoro-2-((3,4,5-Trimethoxyphenyl)Amino)Pyrimidin-4-Yl)Amino)-2,2-Dimethyl-2H-Pyrido[3,2-b][1,4]Oxazin-3(4H)-One Benzenesulfonate

CAS: 841290-81-1

6-((5-Fluoro-2-((3,4,5-Trimethoxyphenyl)Amino)Pyrimidin-4-Yl)Amino)-2,2-Dimethyl-2H-Pyrido[3,2-b][1,4]Oxazin-3(4H)-One Benzenesulfonate

Fórmula: C₂₈H₂₉FN₆O₈S

Pureza: 98%

Peso molecular: 628.63

Ref: 54-PC108892

R406

CAS: 841290-81-1

R406

Fórmula: C₂₂H₂₃FN₆O₅·C₆H₆O₃S

Pureza: ≥95%

Cor e Forma: Solid

Peso molecular: 628.63

Ref: 54-BUP04252

R406

CAS: 841290-81-1

6-((5-Fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one benzenesulfonate

Fórmula: C₂₈H₂₉FN₆O₈S

Pureza: 98%

Peso molecular: 628.63

Ref: IN-DG448256

R406

CAS: 841290-81-1

R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.

Fórmula: C₂₂H₂₃FN₆O₅·C₆H₆O₃S

Pureza: 97.67% - 98.88%

Cor e Forma: White Solid

Peso molecular: 628.63

Ref: TM-T6174

R406

CAS: 841290-81-1

Applications R406 is a potent Syk inhibitor which affects Dectin-1-mediated signalling in mammilian cells. R406 thus acts an anti-fungal agent. Also a potential anti-leukemia agent, through modulation of sphingosine-1 phosphate receptor 1 (S1PR1).
References Borge, M. et al.: J. Immunol., 193, 3165 (2014); Kimura, Y. et al.: J. Biol. Chem., 289, 31565 (2014);

Fórmula: C₂₂H₂₃FN₆O₅·(C₆H₆O₃S)

Cor e Forma: Neat

Peso molecular: 628.6

Ref: TR-R060000

R 406

CAS: 841290-81-1

Inhibitor of SYK kinase

Fórmula: C₂₂H₂₃FN₆O₅•C₆H₆O₃S

Pureza: Min. 95%

Peso molecular: 628.63 g/mol

Ref: 3D-FR103901