CAS 847862-26-4

Fórmula: C12H22N2O2

InChI: InChI=1S/C12H22N2O2/c1-12(2,3)16-11(15)14-10-8-4-5-9(10)7-13-6-8/h8-10,13H,4-7H2,1-3H3,(H,14,15)/t8-,9+,10?

Chave InChI: HHYUNZXSGVNMOY-ULKQDVFKSA-N

SMILES: CC(C)(C)OC(=O)NC1[C@@H]2CC[C@H]1CNC2

tert-Butyl (8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

CAS: 847862-26-4

tert-Butyl (8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

Fórmula: C₁₂H₂₂N₂O₂

Pureza: 97%

Peso molecular: 226.32

Ref: 54-OR1041732

1,1-Dimethylethyl N-(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

CAS: 847862-26-4

Fórmula: C₁₂H₂₂N₂O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 226.3153

Ref: IN-DA00G80B

tert-Butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

CAS: 847862-26-4

tert-Butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

Fórmula: C₁₂H₂₂N₂O₂

Pureza: 98%

Peso molecular: 226.32

Ref: IN-DG435044

tert-butyl (8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

CAS: 847862-26-4

Fórmula: C₁₂H₂₂N₂O₂

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 226.168

Ref: 10-F385737

Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

CAS: 847862-26-4

Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate (tBAA) is a heterocycle that has been modified to enhance its pharmacokinetic properties. Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate was designed to be metabolically stable and have a high bioavailability and isosteric properties with phosphatidylinositol, which it uses as a substrate in the catalytic cycle. This modification also increased tBAA's stability in vivo, leading to an increase in efficacy. The covalent attachment of the phenyl ring on the tertiary amine nitrogen of tBAA provides additional protection against hepatic metabolism by CYP450 enzymes, making it more potent than other compounds with similar structures that are not covalently attached to the amine group.

Fórmula: C₁₂H₂₂N₂O₂

Pureza: Min. 95%

Peso molecular: 226.32 g/mol

Ref: 3D-FT167890