CAS 847949-49-9: 4-(3-chloro-4-fluoro-anilino)-6-(3-morpholinopropoxy)quinazolin-7-ol

Fórmula: C₂₁H₂₂ClFN₄O₃

InChI: InChI=1/C21H22ClFN4O3/c22-16-10-14(2-3-17(16)23)26-21-15-11-20(19(28)12-18(15)24-13-25-21)30-7-1-4-27-5-8-29-9-6-27/h2-3,10-13,28H,1,4-9H2,(H,24,25,26)

O-Desmethyl gefitinib

CAS: 847949-49-9

O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed …

• Fórmula: C₂₁H₂₂ClFN₄O₃
• Pureza: 99.6%
• Cor e Forma: Solid
• Peso molecular: 432.88

7-Quinazolinol,4-[(3-chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-

CAS: 847949-49-9

• Fórmula: C₂₁H₂₂ClFN₄O₃
• Pureza: 98%
• Cor e Forma: Solid
• Peso molecular: 432.8758

O-Desmethyl Gefitinib-d6

CAS: 847949-49-9

• Fórmula: C₂₁H₁₆ClFN₄O₃D₆
• Cor e Forma: Pale Yellow Solid
• Peso molecular: 438.92

O-Desmethyl Gefitinib

CAS: 847949-49-9

• Fórmula: C₂₁H₂₂ClFN₄O₃
• Cor e Forma: Pale Yellow Solid
• Peso molecular: 432.88

4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(morpholin-4-yl)propoxy]quinazolin-7-ol (O-Demethylgefitinib)

CAS: 847949-49-9

• Fórmula: C₂₁H₂₂ClFN₄O₃
• Cor e Forma: Neat
• Peso molecular: 432.88

O-Desmethyl Gefitinib

CAS: 847949-49-9

Stability Hygroscopic Applications A major metabolite of Gefitinib. References Ranson, M., et al.: J. Clin. …

• Fórmula: C₂₁H₂₂ClFN₄O₃
• Cor e Forma: Yellow
• Peso molecular: 432.88

O-Desmethyl gefitinib

CAS: 847949-49-9

Gefitinib is a small-molecule drug that is used for the treatment of non-small cell lung …

• Fórmula: C₂₁H₂₂ClFN₄O₃
• Pureza: Min. 95 Area-%
• Cor e Forma: Powder
• Peso molecular: 432.88 g/mol

O-Desmethyl Gefitinib-d6

CAS: 847949-49-9

• Fórmula: C₂₁D₆H₁₆ClFN₄O₃
• Cor e Forma: Neat
• Peso molecular: 438.913