CAS 885896-54-8

Fórmula: C24H23FN6O2

InChI: InChI=1S/C24H23FN6O2/c1-29-21-20(22(32)30(2)24(29)33)31(14-15-7-9-17(25)10-8-15)23(28-21)26-12-11-16-13-27-19-6-4-3-5-18(16)19/h3-10,13,27H,11-12,14H2,1-2H3,(H,26,28)

Chave InChI: JMZXYZSTEKMPDV-UHFFFAOYSA-N

SMILES: CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)NCCC3=CNC4=CC=CC=C43)CC5=CC=C(C=C5)F

PSB-KK1445

CAS: 885896-54-8

PSB-KK1445 is a potent and selective agonist of GPR18, exhibiting EC50 values of 45.4 nM for humans and 124 nM for mice. The selectivity of PSB-KK1445 for GPR18 over the CB receptor subtypes GPR55 and GPR183 exceeds 200-fold.

Fórmula: C₂₄H₂₃FN₆O₂

Cor e Forma: Solid

Peso molecular: 446.48

Ref: TM-T88797