CAS 88898-17-3

Peptídeo natriurético atrial-28 (rato) (9CI)

Descrição:

O peptídeo natriurético atrial (ANP) é um hormônio produzido principalmente pelas células atriais do coração, desempenhando um papel crucial na regulação da pressão arterial e do equilíbrio de fluidos. A variante específica, peptídeo natriurético atrial-28 (rato) (9CI), é um peptídeo composto por 28 aminoácidos, que está envolvido na promoção da natriurese, a excreção de sódio pela urina. Este peptídeo atua ligando-se a receptores específicos nos rins e vasos sanguíneos, levando à vasodilatação e ao aumento da excreção renal de sódio, reduzindo assim o volume e a pressão sanguínea. O ANP também é conhecido por seus efeitos antagônicos sobre o sistema renina-angiotensina-aldosterona, contribuindo ainda mais para seu papel na homeostase cardiovascular. O número CAS 88898-17-3 identifica esta variante específica de peptídeo, que é frequentemente utilizada em pesquisas para estudar a fisiologia cardiovascular e as potenciais aplicações terapêuticas em condições como hipertensão e insuficiência cardíaca. Sua estabilidade, solubilidade e atividade biológica fazem dele uma ferramenta valiosa tanto na pesquisa biomédica básica quanto aplicada.

Fórmula: C₁₂₈H₂₀₅N₄₅O₃₉S₂

InChI: InChI=1S/C128H205N45O39S2/c1-10-64(7)99-121(209)151-52-94(183)152-66(9)101(189)156-77(36-37-91(130)180)109(197)167-85(56-175)105(193)150-53-96(185)154-78(43-62(3)4)103(191)149-54-97(186)155-89(119(207)164-82(48-92(131)181)114(202)169-86(57-176)116(204)163-81(46-68-25-16-13-17-26-68)113(201)159-74(29-20-40-144-126(136)137)107(195)166-84(123(211)212)47-69-32-34-70(179)35-33-69)60-213-214-61-90(171-118(206)88(59-178)170-117(205)87(58-177)168-108(196)75(30-21-41-145-127(138)139)157-106(194)73(28-19-39-143-125(134)135)158-112(200)79(44-63(5)6)161-102(190)71(129)55-174)120(208)162-80(45-67-23-14-12-15-24-67)104(192)148-50-93(182)147-51-95(184)153-72(27-18-38-142-124(132)133)110(198)173-100(65(8)11-2)122(210)165-83(49-98(187)188)115(203)160-76(111(199)172-99)31-22-42-146-128(140)141/h12-17,23-26,32-35,62-66,71-90,99-100,174-179H,10-11,18-22,27-31,36-61,129H2,1-9H3,(H2,130,180)(H2,131,181)(H,147,182)(H,148,192)(H,149,191)(H,150,193)(H,151,209)(H,152,183)(H,153,184)(H,154,185)(H,155,186)(H,156,189)(H,157,194)(H,158,200)(H,159,201)(H,160,203)(H,161,190)(H,162,208)(H,163,204)(H,164,207)(H,165,210)(H,166,195)(H,167,197)(H,168,196)(H,169,202)(H,170,205)(H,171,206)(H,172,199)(H,173,198)(H,187,188)(H,211,212)(H4,132,133,142)(H4,134,135,143)(H4,136,137,144)(H4,138,139,145)(H4,140,141,146)/t64-,65-,66-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,99-,100-/m0/s1

Chave InChI: QGFSVPWZEPKNDV-BRTFOEFASA-N

SMILES: CC[C@H](C)[C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCNC(=N)N)CC(=O)O)[C@@H](C)CC)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O)CC(C)C)CO)CCC(=O)N)C

Sinónimos:

• Atriopeptin-33(rat), 1-de-L-leucine-2-de-L-alanine-3-deglycine-4-de-L-proline-5-de-L-arginine-
• 1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecaazacyclotripentacontane,cyclic peptide deriv.
• (1-28)-Rat atrial natriuretic peptide
• (99-126)-Ratatrial natriuretic factor
• (99-126)-Rat atrial natriuretic polypeptide
• (99-126)-Ratatriopeptin
• 1-28-Rat atriopeptin
• 12: PN: WO2007058336 SEQID: 12 claimedprotein
• Alpha rat atrial natriuretic polypeptide
• L-Tyrosine,L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-isoleucyl-L-a-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-,cyclic (7® 23)-disulfide
• Rat atrialnatriuretic factor(1-28)
• Rat atrial natriuretic factor(99-126)
• Rat atrialnatriuretic factor-28
• Rat atrial natriuretic peptide(1-28)
• Rat atrialnatriuretic peptide(99-126)
• Rat atrial natriuretic peptide-28
• Ratatriopeptin(1-28)
• Rat atriopeptin(99-126)
• Rat atriopeptin-28
• Rat natriureticpeptide(1-28)
• Rat a-atrial natriuretic peptide
• Rat a-atrial natriuretic peptide(1-28)
• Rat a-atriopeptin
• a-Atriopeptin (rat)
• a-Rat atrial natriureticpolypeptide
• a-Ratatriopeptin(1-28)

Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat)

CAS: 88898-17-3

Bachem ID: 4030380.

Fórmula: C₁₂₈H₂₀₅N₄₅O₃₉S₂

Pureza: 97.9%

Cor e Forma: White Powder

Peso molecular: 3062.45

Ref: 01-4030380

Atrial Natriuretic Peptide (ANP) (1-28), rat

CAS: 88898-17-3

Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.

Fórmula: C₁₂₈H₂₀₅N₄₅O₃₉S₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 3062.41

Ref: TM-TP1221

Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat) H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond)

CAS: 88898-17-3

Fórmula: C₁₂₈H₂₀₅N₄₅O₃₉S₂

Pureza: 98%

Peso molecular: 3062.4054

Ref: IN-DA01E9N4

ANP (Rat, 1-28)

CAS: 88898-17-3

ANP (Rat, 1-28) is a peptide that belongs to the group of activators. It has been used as a research tool for studying ion channels and receptor interactions. ANP (Rat, 1-28) can be used as an inhibitor in pharmacology experiments on ligands and their receptors. This peptide can be purified to high purity, with a CAS number of 88898-17-3.

Fórmula: C₁₂₈H₂₀₅N₄₅O₃₉S₂

Pureza: Min. 95%

Peso molecular: 3,062.4 g/mol

Ref: 3D-PAF-4151-S

Atrial Natriuretic Peptide (1-28), rat

CAS: 88898-17-3

Atrial Natriuretic Peptide (1-28), rat is a recombinant peptide that belongs to the group of ligands. It binds to the receptor and activates or inhibits it. Atrial Natriuretic Peptide (1-28), rat is used as a research tool for studying the function of ion channels, protein interactions, and pharmacology. The antibody has been shown to have high purity and is suitable for use in cell biology and pharmacology research.

Fórmula: C₁₂₈H₂₀₅N₄₅O₃₉S₂

Pureza: Min. 95%

Peso molecular: 3,062.41 g/mol

Ref: 3D-FA73200