CAS 894804-07-0

Fórmula: C18H20N4O4

InChI: InChI=1S/C18H20N4O4/c1-4-26-18-13(10-19)14(20)9-16(22-18)21-17(23)8-11-7-12(24-2)5-6-15(11)25-3/h5-7,9H,4,8H2,1-3H3,(H3,20,21,22,23)

Chave InChI: KQMPRSZTUSSXND-UHFFFAOYSA-N

SMILES: CCOC1=C(C(=CC(=N1)NC(=O)CC2=C(C=CC(=C2)OC)OC)N)C#N

N-(4-Amino-5-Cyano-6-Ethoxypyridin-2-Yl)-2-(2,5-Dimethoxyphenyl)Acetamide

CAS: 894804-07-0

N-(4-Amino-5-Cyano-6-Ethoxypyridin-2-Yl)-2-(2,5-Dimethoxyphenyl)Acetamide

Fórmula: C₁₈H₂₀N₄O₄

Pureza: 98%

Peso molecular: 356.38

Ref: 54-OR1024296

JNK Inhibitor VIII

CAS: 894804-07-0

JNK Inhibitor VIII

Fórmula: C₁₈H₂₀N₄O₄

Pureza: 98.5%

Cor e Forma: Solid

Peso molecular: 356.38

Ref: 54-BUP03066

N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide

CAS: 894804-07-0

Fórmula: C₁₈H₂₀N₄O₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 356.3758

Ref: IN-DA0087RS

N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide

CAS: 894804-07-0

N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide

Fórmula: C₁₈H₂₀N₄O₄

Pureza: 98%

Peso molecular: 356.38

Ref: IN-DG00792759

JNK Inhibitor VIII

CAS: 894804-07-0

JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2,

Fórmula: C₁₈H₂₀N₄O₄

Pureza: 98.93%

Cor e Forma: Solid

Peso molecular: 356.38

Ref: TM-T7677

JNK Inhibitor VIII

CAS: 894804-07-0

Pureza: 98%

Peso molecular: 356.148

Ref: 10-F840736

JNK Inhibitor VIII

Produto Controlado

CAS: 894804-07-0

Applications JNK Inhibitor VIII is an inhibitor shown to suppress apoptosis, caspase cleavage, and cytochrome C release.

Fórmula: C₁₈H₂₀N₄O₄

Cor e Forma: Neat

Peso molecular: 356.376

Ref: TR-J211273

JNK Inhibitor VIII

CAS: 894804-07-0

JNK inhibitor VIII is a potent, selective and cell-permeable JNK inhibitor that is effective in inhibiting the activation of pro-inflammatory genes. It has been shown to inhibit the proliferation and induce apoptosis in leukemia cells, as well as blocking the growth of primary human prostate cancer cells. JNK inhibitor VIII blocks ubiquitin ligases involved in protein degradation and mitochondrial membrane potential, which induces reactive oxygen species (ROS) production by mitochondria. This leads to an increase in cytosolic Ca2+, c-jun phosphorylation, and potential drug target for cancer therapy.

Fórmula: C₁₈H₂₀N₄O₄

Pureza: Min. 95%

Peso molecular: 356.38 g/mol

Ref: 3D-UKB80407