CAS 90365-57-4

(2S,5S)-1,2,4,5,6,8-Hexahidro-5-(hidroximetil)-1-metil-2-(1-metiletil)-3H-pirrolo[4,3,2-gh]-1,4-benzodiazonin-3-ona

Descrição:

Indolactam V (-) (90365-57-4) is a PKC activator acting at the phorbol ester binding site.1,2?Directs differentiation of human and mouse ESCs to pancreatic cells.3?? May be used, along with other agents, to differentiate human iPS cells into glucose-responsive insulin-secreting progeny.4?Increases regulator of G protein signaling 2 (RGS2) protein levels, a protein that regulates GPCR signaling.5

Fórmula: C₁₇H₂₃N₃O₂

InChI: InChI=1/C17H23N3O2/c1-10(2)16-17(22)19-12(9-21)7-11-8-18-13-5-4-6-14(15(11)13)20(16)3/h4-6,8,10,12,16,18,21H,7,9H2,1-3H3,(H,19,22)/t12-,16-/m0/s1

Chave InChI: InChIKey=LUZOFMGZMUZSSK-LRDDRELGSA-N

SMILES: CN1C2=C3C(C[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)C)=CNC3=CC=C2

Sinónimos:

• (-)-Ilv
• (2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one
• (2S,5S)-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one
• 3H-Pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one, 1,2,4,5,6,8-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-, (2S,5S)-
• 3H-Pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one, 1,2,4,5,6,8-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-, (2S-(2R*,5R*))-
• Brn 4711877
• (-)-Indolactam V
• Indolactam V
• 3h-pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one,1,2,4,5,6,8-hexahydro-5-(hydroxym
• (-)-Indolactam V&nbsp
• IndolactaM

(-)-Indolactam V

CAS: 90365-57-4

(-)-Indolactam V

Fórmula: C₁₇H₂₃N₃O₂

Pureza: 99.30%

Peso molecular: 301.38

Ref: 54-OR1111950

(-)-Indolactam V

CAS: 90365-57-4

Fórmula: C₁₇H₂₃N₃O₂

Pureza: 99.30%

Cor e Forma: Solid

Peso molecular: 301.3834

Ref: IN-DA006QY8

(-)-Indolactam V

CAS: 90365-57-4

Fórmula: C₁₇H₂₃N₃O₂

Pureza: ≥ 97.0%

Cor e Forma: White to off-white powder

Peso molecular: 301.4

Ref: 7W-GL4102

(-)-Indolactam V

CAS: 90365-57-4

Fórmula: C₁₇H₂₃N₃O₂

Pureza: 99.30%

Peso molecular: 301.39

Ref: 10-F050739

(-)-Indolactam V

Produto Controlado

CAS: 90365-57-4

Fórmula: C₁₇H₂₃N₃O₂

Cor e Forma: Neat

Peso molecular: 301.383

Ref: TR-I577325

(-)-Indolactam V-d8

Produto Controlado

CAS: 90365-57-4

Fórmula: C₁₇D₈H₁₅N₃O₂

Cor e Forma: Neat

Peso molecular: 309.433

Ref: TR-I577327

(-)-Indolactam V

CAS: 90365-57-4

(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.

Fórmula: C₁₇H₂₃N₃O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 301.38

Ref: TM-T17299