CAS 906737-25-5

Pyridin-3-yl 4-(phenylcarbamoyl)piperidine-1-carboxylate

CAS: 906737-25-5

Pyridin-3-yl 4-(phenylcarbamoyl)piperidine-1-carboxylate

Fórmula: C₁₈H₁₉N₃O₃

Pureza: 98%

Peso molecular: 325.37

Ref: 54-OR1061595

ASP8477

CAS: 906737-25-5

ASP8477 is a potent and selective FAAH inhibitor. It increases anandamide levels in the brain when administered orally. In rat models of neuropathic and osteoarthritic pain, ASP8477 demonstrates significant efficacy without causing motor coordination issues. A single oral dose of ASP8477 improves thermal hyperalgesia and cold allodynia in rats with chronic constriction nerve injury. Moreover, ASP8477 restores the decreased muscle pressure threshold in a myalgia model induced by reserpine. Research indicates that ASP8477 possesses analgesic effects effective for alleviating neuropathic and functional pain, making its pharmacological properties suitable for chronic pain treatment.

Fórmula: C₁₈H₁₉N₃O₃

Cor e Forma: Solid

Peso molecular: 325.36

Ref: TM-T201960

ASP 8477

CAS: 906737-25-5

Pyridin-3-yl 4-(phenylcarbamoyl)piperidine-1-carboxylate

Fórmula: C₁₈H₁₉N₃O₃

Pureza: 98%

Peso molecular: 325.36

Ref: IN-DG01314355