CAS 928205-59-8

Fórmula: C20H22O9

InChI: InChI=1S/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1-/t15-,16-,17+,18-,20+/m1/s1

Chave InChI: JAYVHSBYKLLDJC-ZPBLDHPVSA-N

SMILES: C1=CC(=CC=C1/C=C\C2=C(C(=CC(=C2)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O

cis-THSG

CAS: 928205-59-8

cis-THSG is an orally active and selective inhibitor of DNA topoisomerase II (DNAtopoisomeraseII), with no inhibitory activity against DNA topoisomerase I. It can inhibit the transcriptional expression of phosphoenolpyruvate carboxykinase (PEPCK). cis-THSG lowers blood glucose levels in male CF-1 mice with diet-induced diabetes, improves glucose intolerance, and alleviates insulin resistance. It is applicable in research related to type 2 diabetes.

Fórmula: C₂₀H₂₂O₉

Peso molecular: 406.38

Ref: TM-TN13934