CAS 930772-88-6

Fórmula: C27H31N3O5

InChI: InChI=1S/C27H31N3O5/c1-2-3-6-9-24(31)28-22-16-12-20(13-17-22)27(34)21-14-18-23(19-15-21)29-25(32)10-7-4-5-8-11-26(33)30-35/h1,12-19,35H,3-11H2,(H,28,31)(H,29,32)(H,30,33)

Chave InChI: VHTATGLVGGHVIS-UHFFFAOYSA-N

SMILES: C#CCCCC(=O)NC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)NC(=O)CCCCCCC(=O)NO

N1-Hydroxy-N8-[4-[4-[(1-oxo-5-hexyn-1-yl)amino]benzoyl]phenyl]-octanediamide

CAS: 930772-88-6

N1-Hydroxy-N8-[4-[4-[(1-oxo-5-hexyn-1-yl)amino]benzoyl]phenyl]-octanediamide is a molecule with chemical structure of a benzamide. It has been shown to have inhibitory properties against histone deacetylase (HDAC), an enzyme that regulates gene expression by removing acetyl groups from the lysine residues in histones. The compound was found to be an estrogen receptor modulator and inhibits the growth of cancer cells in culture. In rat cardiomyocytes, it increased contractility and inhibited calcium uptake. N1-Hydroxy-N8-[4-[4-[(1-oxo-5-hexyn-1-yl)amino]benzoyl]phenyl]-octanediamide binds to the protein target HDAC2, which is associated with breast cancer progression, highlighting its potential as a therapeutic drug for

Fórmula: C₂₇H₃₁N₃O₅

Pureza: Min. 95%

Peso molecular: 477.6 g/mol

Ref: 3D-FMB77288

SAHA-BPyne

CAS: 930772-88-6

SAHA is an HDAC inhibitor; its derivative SAHA-BPyne labels proteins in cells/proteomes, used in click chemistry, with an IC50 of ~3 μM.

Fórmula: C₂₇H₃₁N₃O₅

Cor e Forma: Solid

Peso molecular: 477.55

Ref: TM-T35765