CAS 942425-68-5

PHA-767491 (hydrochloride)

CAS: 942425-68-5

Fórmula: C₁₂H₁₂ClN₃O

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 249.6962

Ref: IN-DA00GU9D

PHA-767491 hydrochloride

CAS: 942425-68-5

PHA-767491 hydrochloride

Fórmula: C₁₂H₁₂ClN₃O

Pureza: ≥98%

Peso molecular: 249.69

Ref: 54-BUP15519

PHA-767491 hydrochloride

CAS: 942425-68-5

PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.

Fórmula: C₁₂H₁₂ClN₃O

Pureza: 99.56% - 99.92%

Cor e Forma: White Solid

Peso molecular: 249.69

Ref: TM-T6940

PHA-767491

CAS: 942425-68-5

PHA-767491 is a compound that blocks the activity of Bcl-2, which is an anti-apoptotic protein. It inhibits the transcriptional regulation of genes that promote cell survival and blocks the production of proteins involved in cell proliferation. PHA-767491 has been shown to be effective in treating cancer cells by inhibiting the production of molecules such as epidermal growth factor and tumor necrosis factor (TNF). This drug also inhibits the mitochondrial membrane potential, which leads to apoptosis or cell death.

Fórmula: C₁₂H₁₁N₃O·HCl

Pureza: Min. 95%

Peso molecular: 249.7 g/mol

Ref: 3D-SMB42568