CAS 944808-88-2

Fórmula: C18H17ClFN5O2

InChI: InChI=1S/C18H17ClFN5O2/c1-11-21-24-18(26-11)15-4-5-17(23-22-15)25-8-6-13(7-9-25)27-16-10-12(20)2-3-14(16)19/h2-5,10,13H,6-9H2,1H3

Chave InChI: WFOFPVXMPTVOTJ-UHFFFAOYSA-N

SMILES: CC1=NN=C(O1)C2=NN=C(C=C2)N3CCC(CC3)OC4=C(C=CC(=C4)F)Cl

CAY10566

CAS: 944808-88-2

CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.

Fórmula: C₁₈H₁₇ClFN₅O₂

Pureza: 99.54% - 99.75%

Cor e Forma: Solid

Peso molecular: 389.811

Ref: TM-T14878

CAY10566

CAS: 944808-88-2

CAY10566

Fórmula: C₁₈H₁₇ClFN₅O₂

Pureza: 99.5%

Peso molecular: 389.81

Ref: 54-BUP08559

2-(6-(4-(2-Chloro-5-fluorophenoxy)piperidin-1-yl)pyridazin-3-yl)-5-methyl-1,3,4-oxadiazole

CAS: 944808-88-2

Fórmula: C₁₈H₁₇ClFN₅O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 389.8113

Ref: IN-DA003OPY

2-(6-(4-(2-Chloro-5-fluorophenoxy)piperidin-1-yl)pyridazin-3-yl)-5-methyl-1,3,4-oxadiazole

CAS: 944808-88-2

2-(6-(4-(2-Chloro-5-fluorophenoxy)piperidin-1-yl)pyridazin-3-yl)-5-methyl-1,3,4-oxadiazole

Fórmula: C₁₈H₁₇ClFN₅O₂

Pureza: 98%

Peso molecular: 389.81

Ref: IN-DG379810

CAY 10566

Produto Controlado

CAS: 944808-88-2

Applications CAY10566, is a stearoyl-CoA desaturase (SCD) inhibitor.
References Masuda M. et al.: J Lipid Res. 2012 Aug;53(8):1543-52.;

Fórmula: C₁₈H₁₇ClFN₅O₂

Cor e Forma: Neat

Peso molecular: 389.81

Ref: TR-C227125

CAY10566

CAS: 944808-88-2

CAY10566 is a novel compound that has been shown to induce apoptosis in cells. It binds to the cytosolic protein cytochrome c, which is involved in the mitochondrial electron transport chain. This binding leads to an increase of intracellular levels of hydrogen peroxide and reactive oxygen species (ROS), leading to increased cell apoptosis. CAY10566 also inhibits autophagy, a process that assists in the degradation of cellular components during starvation or other unfavorable conditions. This drug was also found to inhibit cell growth and proliferation by suppressing the MAPK/AMPK pathway, which regulates cellular metabolism and growth.

Fórmula: C₁₈H₁₇ClFN₅O₂

Pureza: Min. 95%

Peso molecular: 389.82 g/mol

Ref: 3D-UMB80888