CAS 94790-37-1

1-[Bis(dimetilamino)metileno]-1H-benzotriazólio hexafluorofosfato(1-) 3-óxido

Descrição:

1-[Bis(dimetilamino)metileno]-1H-benzotriazólio hexafluorofosfato(1-) 3-óxido, comumente referido pelo seu número CAS 94790-37-1, é um composto químico que apresenta um moiety de benzotriazole, conhecido por suas aplicações em vários campos, incluindo síntese orgânica e ciência dos materiais. Este composto é caracterizado por sua estrutura única que inclui um grupo bis(dimetilamino)methylene, contribuindo para sua reatividade e potencial como agente nucleofílico. A presença do ânion hexafluorofosfato indica interações iônicas fortes, o que pode aumentar a solubilidade em solventes polares. Além disso, o grupo funcional 3-óxido pode conferir propriedades eletrônicas específicas, tornando-o útil em aplicações fotocatalíticas. O composto é tipicamente manuseado com cuidado devido à sua potencial toxicidade e reatividade, e é frequentemente utilizado em ambientes de laboratório controlados. Suas aplicações podem se estender a áreas como catálise, síntese de corantes e como reagente em transformações orgânicas, demonstrando sua versatilidade em pesquisa e desenvolvimento químico.

Fórmula: C₁₁H₁₆N₅O·F₆P

InChI: InChI=1S/C11H16N5O.F6P/c1-13(2)11(14(3)4)15-9-7-5-6-8-10(9)16(17)12-15;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1

Chave InChI: InChIKey=BSKUEERROYGAFF-UHFFFAOYSA-N

SMILES: C(N(C)C)(N(C)C)=[N+]1C=2C(N(=O)=N1)=CC=CC2.[P+5]([F-])([F-])([F-])([F-])([F-])[F-]

Sinónimos:

• 1-[Bis(dimethylamino)methylene]-1H-benzotriazolium hexafluorophosphate(1-) 3-oxide
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, hexafluorophosphate(1-) (1:1)
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, hexafluorophosphate(1-), 3-oxide
• 2-(1H-Benzotriazole-1-Yl)-1,1,3,3-Tetramethyluronium Hexafluorophosphate
• Hbtu
• N-Hbtu
• N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylidene]-N-methylmethanaminium hexafluorophosphate
• O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Hexafluorophosphate
• O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluoro-phosphate
• O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluorophosphate

HBTU [Coupling Reagent for Peptide]

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: >98.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 379.25

Ref: 3B-B1657

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98%

CAS: 94790-37-1

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is used as a coupling reagent for solid-phase peptide synthesis. It has been shown to effectively suppress racemization. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. S

Fórmula: C₁₁H₁₆N₅O

Pureza: 98%

Cor e Forma: Crystalline powder, White to pale cream

Peso molecular: 234.28

Ref: 02-B23597

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

Fórmula: C₁₁H₁₆N₅O·PF₆

Pureza: ≥95%

Cor e Forma: White Solid-Crystals

Peso molecular: 379.24181

Ref: 54-PC6587

HBTU

CAS: 94790-37-1

HBTU is a uronium peptide coupling agent used in research laboratories. Literature indicates that HBTU, along with related agents HATU and HCTU, poses a special hazard as an immune sensitizer. Documented cases describe skin irritation, allergic reactions, and anaphylaxis induced by repeated laboratory exposure. Safe handling protocols are recommended to minimize risk.

Fórmula: C₁₁H₁₆F₆N₅OP

Peso molecular: 379.2418

Ref: TM-TXB-00812

HBTU

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: ≥ 99.0%

Cor e Forma: White to almost white powder or crystals

Peso molecular: 379.25

Ref: 7W-GE0864

O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 379.2418

Ref: IN-DA0035F7

HBTU

CAS: 94790-37-1

1-(Bis(dimethylamino)methylene)-1H-benzo[d][1,2,3]triazole-1-ium 3-oxide hexafluorophosphate(V)

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: 98%

Peso molecular: 379.24

Ref: IN-DG23222

HBTU Reagent

CAS: 94790-37-1

HBTU is a reagent that is used in the synthesis of peptides. It has been shown to have inhibitory properties and stable complexes with ester linkages. HBTU has been shown to have a negative effect on congestive heart disease, which may be due to its ability to bind to receptors and mimic the effects of peptide hormones. This compound is also used as a model system for mitochondrial membrane potential. HBTU binds covalently to the peptide hormone receptor, which slows down the rate of degradation and increases its resistance to proteases. HBTU can also be used as an immunosuppressant drug in animal models of autoimmune diseases by inhibiting T-cell proliferation and cytokine production.

Fórmula: C₁₁H₁₆N₅OPF₆

Pureza: Min. 95%

Peso molecular: 379.25 g/mol

Ref: 3D-KHB-1065-PI

HBTU

CAS: 94790-37-1

HBTU is a common reagent used for peptide coupling, which can be employed for amide and ester formation. It is stable, highly reactive, suitable for solid phase and in-solution synthesis. The major advantages of HBTU are high yields, fast reaction times, easy reaction conditions, racemisation control and ease of purification from the water-soluble by-products. HBTU contains both the carbodiimide function and the benzotriazole one, activating the carboxylic acid and forming HOBt in situ. Although HBTU was originally catalogued as uronium salt, X-ray diffraction showed evidence for it to be an aminium salt instead.

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: Min. 99 Area-%

Cor e Forma: White Powder

Peso molecular: 379.24 g/mol

Ref: 3D-FH07095

O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: 99.0%

Cor e Forma: Solid

Peso molecular: 379.247

Ref: 10-F009019

HBTU extrapure, 98%

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: min. 98 %

Cor e Forma: White, Crystalline powder

Peso molecular: 379.25

Ref: SR-44424