
CAS 952652-79-8
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Foram encontrados 10 produtos.
Valsartan Related Compound B (N-butyryl-N-{[2'-(1H-tetrazole-5-yl)-biphenyl-4-yl]methyl}-L-valine)
CAS:Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFórmula:C23H27N5O3Cor e Forma:White PowderPeso molecular:421.21139(S)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)butyramido)-3-methylbutanoic acid
CAS:(S)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)butyramido)-3-methylbutanoic acidFórmula:C23H27N5O3Pureza:98%Peso molecular:421.49Valsartan EP Impurity C (Valsartan USP Related Compound B)
CAS:Fórmula:C23H27N5O3Cor e Forma:Off-White SolidPeso molecular:421.50Valsartan n-Propyl Impurity
CAS:Produto ControladoImpurity Valsartan Related Compound B
Applications Valsartan n-Propyl is an impurity in the synthesis of Valsartan (V095750). Valsartan USP Related Compound B.
References Hillaert, S., et al.: J. Pharm. Biomed. Anal., 31, 329 (2003), Carlucci, G., et al.: Anal. Lett., 33, 2491 (2000), Cagigal, E., et al.: Talanta, 54, 1121 (2001),Fórmula:C23H27N5O3Cor e Forma:NeatPeso molecular:421.49(S)-N-Butyryl-N-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]valine
CAS:(S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)butyramido)-3-methylbutanoic acidFórmula:C23H27N5O3Pureza:98%Peso molecular:421.49N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
CAS:N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine (GW1929) is a potent vasodilator that is used for the treatment of hypertension. It is synthesized by condensation of sodium hydroxide with 2-(4′-chlorophenyl)piperazine followed by methyl esterification and chloride acylation. The synthesis of GW1929 has been accomplished in two steps: carbonate cyclization and valsartan hydrolysis. In the first step, the carboxylic acid group of GW1929 was converted to its corresponding chloride compound which was then reacted with methyl bromide to yield the desired product. The second step involved hydrolysis of GW1929 with potassium carbonate, after which it was oxidized with azide to form an ester. SodiumFórmula:C23H27N5O3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:421.49 g/mol








