CAS 953769-46-5

Fórmula: C20H22N4O3S

InChI: InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1

Chave InChI: ADZBMFGQQWPHMJ-RHSMWYFYSA-N

SMILES: CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)N[C@@H]4CCCC[C@H]4O

4-((2-(((1R,2R)-2-Hydroxycyclohexyl)Amino)Benzo[D]Thiazol-6-Yl)Oxy)-N-Methylpicolinamide

CAS: 953769-46-5

4-((2-(((1R,2R)-2-Hydroxycyclohexyl)Amino)Benzo[D]Thiazol-6-Yl)Oxy)-N-Methylpicolinamide

Fórmula: C₂₀H₂₂N₄O₃S

Pureza: 98%

Peso molecular: 398.48

Ref: 54-OR1024387

Sotuletinib

CAS: 953769-46-5

Sotuletinib

Fórmula: C₂₀H₂₂N₄O₃S

Pureza: 99.5%

Peso molecular: 398.48

Ref: 54-BUP15067

4-((2-(((1R,2R)-2-Hydroxycyclohexyl)amino)benzo[d]thiazol-6-yl)oxy)-N-methylpicolinamide

CAS: 953769-46-5

4-((2-(((1R,2R)-2-Hydroxycyclohexyl)amino)benzo[d]thiazol-6-yl)oxy)-N-methylpicolinamide

Fórmula: C₂₀H₂₂N₄O₃S

Pureza: 98%

Peso molecular: 398.48

Ref: IN-DG303841

BLZ-945

CAS: 953769-46-5

Fórmula: C₂₀H₂₂N₄O₃S

Pureza: ≥ 98.0%

Cor e Forma: White to off-white powder

Peso molecular: 398.5

Ref: 7W-GL2252

Sotuletinib

CAS: 953769-46-5

Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.

Fórmula: C₂₀H₂₂N₄O₃S

Pureza: 97.43% - 99.82%

Cor e Forma: Yellow Solid

Peso molecular: 398.48

Ref: TM-T6119

4-((2-(((1R,2R)-2-HYDROXYCYCLOHEXYL)AMINO)BENZO[D]THIAZOL-6-YL)OXY)-N-METHYLPICOLINAMIDE

CAS: 953769-46-5

Fórmula: C₂₀H₂₂N₄O₃S

Pureza: 98%

Peso molecular: 398.48

Ref: 10-F501110

BLZ 945

CAS: 953769-46-5

BLZ 945 is a novel small molecule that inhibits the activation of microglia, which are immune cells in the brain. It has been shown to inhibit tumor growth and radiation-induced tissue damage in cancer research. BLZ 945 also reduces the severity of autoimmune diseases by inhibiting the production of pro-inflammatory cytokines such as csf-1r and toll-like receptor 4. In addition, it has anti-inflammatory properties due to its inhibition of macrophage migration and adhesion. The drug has been shown to reduce the size of solid tumours in mice by reducing tumor angiogenesis and inhibiting cell proliferation.

Fórmula: C₂₀H₂₂N₄O₃S

Pureza: Min. 95%

Peso molecular: 398.48 g/mol

Ref: 3D-BB178452

4-[[2-[[(1R,2R)-2-Hydroxycyclohexyl]amino]-6-benzothiazolyl]oxy]-N-methyl-2-pyridinecarboxamide

CAS: 953769-46-5

Fórmula: C₂₀H₂₂N₄O₃S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 398.4787

Ref: IN-DA00368U