CAS 97-67-6
:Ácido L-málico
Descrição:
Ácido L-málico, com o número CAS 97-67-6, é um composto orgânico que ocorre naturalmente e é classificado como um ácido dicarboxílico. É um sólido cristalino incolor e sem odor que é solúvel em água e tem um sabor ligeiramente azedo, comumente encontrado em várias frutas, particularmente maçãs. Ácido L-málico desempenha um papel crucial no ciclo de Krebs, uma via metabólica chave para a produção de energia em organismos vivos. Sua fórmula molecular é C4H6O5, e apresenta dois grupos funcionais carboxila (-COOH), que contribuem para sua acidez e reatividade. Ácido L-málico é utilizado na indústria alimentícia como um agente aromatizante e acidulante, melhorando o sabor de bebidas e doces. Além disso, tem aplicações nas indústrias cosmética e farmacêutica devido à sua capacidade de atuar como regulador de pH e agente quelante. O composto é geralmente reconhecido como seguro (GRAS) quando utilizado em produtos alimentícios, e sua natureza biodegradável o torna uma opção ambientalmente amigável em várias aplicações.
Fórmula:C4H6O5
InChI:InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
Chave InChI:InChIKey=BJEPYKJPYRNKOW-REOHCLBHSA-N
SMILES:[C@H](CC(O)=O)(C(O)=O)O
Sinónimos:- (-)-(S)-Malic acid
- (-)-<span class="text-smallcaps">L</span>-Malic acid
- (-)-Hydroxysuccinic acid
- (-)-L-Malic acid
- (-)-Malic acid
- (2S)-2-Hydroxybutanedioic acid
- (2S)-2-Hydroxysuccinic acid
- (2S)-Malic acid
- (S)-2-Hydroxysuccinic acid
- <span class="text-smallcaps">L</span>-Apple acid
- Acide L-malique
- Apple acid
- Butanedioic acid, 2-hydroxy-, (2S)-
- Butanedioic acid, hydroxy-, (S)-
- L-Apfelsaure
- Malic Acid, L-
- Malic acid, <span class="text-smallcaps">L</span>-
- Nsc 9232
- S-2-Hydroxybutanedioic acid
- acido L-malico
- L-Hydroxysuccinic acid
- (S)-(-)-Hydroxysuccinic acid
- L-Maleic Acid
- (2S)-2-hydroxybutanedioate
- Butanedioic acid, hydroxy-, (2S)-
- (S)-HYDROXYBUTANEDIOIC ACID
- HYDROXYBUTANEDIOIC ACID
- L-(-)-APPLE ACID
- 1-HYDROXYSUCCINIC ACID
- L-HYDROXYBUTANEDIOIC ACID
- 2-HYDROXYSYCCINIC ACID
- (S)-2-HYDROXYBUTANEDICARBOXYLIC ACID
- L(-)-MALATE
- NATURAL APPLE ACID
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L-(-)-Malic Acid
CAS:Fórmula:C4H6O5Pureza:>98.0%(T)Cor e Forma:White to Almost white powder to crystalPeso molecular:134.09L-(-)-Malic acid, 97%
CAS:L-(-)-Malic acid is used as Selective -amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including -opioid rece. It also acts as active ingredient in many sour or tart foods. It is used as synthesizing disincrustant and fluorescent whiteniFórmula:C4H6O5Pureza:97%Cor e Forma:White, Crystals or powder or crystalline powderPeso molecular:134.09L-(-)-Malic acid, 99%
CAS:L-(-)-Malic acid is used as a food additive, Selective -amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including -opioid receptor agonists, 1,25-dihydroxyvitamin D3 analogue, and phoslactomycin B. This Thermo Scientific Chemicals brandFórmula:C4H6O5Pureza:99%Cor e Forma:White, Powder or crystals or crystalline powderPeso molecular:134.09L-Malic acid, ≥99%
CAS:Thermo Scientific L-Malic acidFórmula:C4H6O5Pureza:99%Cor e Forma:White crystalline powderPeso molecular:134.09L-(-)-Malic acid
CAS:Fórmula:C4H6O5Pureza:(Titration) ≥ 99.0%Cor e Forma:White to almost white powder or crystalsPeso molecular:134.09(S)-(-)-Malic-2,3,3-d3 Acid93% enantiomeric purity)
CAS:Fórmula:HOOCCD2CD(OH)COOHPureza:98 atom % DCor e Forma:White SolidPeso molecular:137.04035(S)-Malic acid (Standard)
CAS:(S)-Malic acid (Standard) is the standard substance of (S)-Malic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple. Malic acid can make a wine taste tart, although the amount decreases with increasing fruit ripeness. (wikipedia). In its ionized form malic acid is called malate. Malate is an intermediate of the TCA cycle along with fumarate. It can also be formed from pyruvate as one of the anaplerotic reactions. In humans, malic acid is both derived from food sources and synthesized in the body through the citric acid cycle or Krebs cycle which takes place in the mitochondria. Malate's importance to the production of energy in the body during both aerobic and anaerobic conditions is well established. Under aerobic conditions, the oxidation of malate to oxaloacetate provides reducing equivalents to the mitochondria through the malate-aspartate redox shuttle. During anaerobic conditions, where a buildup of excess of reducing equivalents inhibits glycolysis, malic acid's simultaneous reduction to succinate and oxidation to oxaloacetate is capable of removing the accumulating reducing equivalents. This allows malic acid to reverse hypoxia's inhibition of glycolysis and energy production. In studies on rats it has been found that only tissue malate is depleted following exhaustive physical activity. Other key metabolites from the citric acid cycle needed for energy production were found to be unchanged. Because of this, a deficiency of malic acid has been hypothesized to be a major cause of physical exhaustion. Notably, the administration of malic acid to rats has been shown to elevate mitochondrial malate and increase mitochondrial respiration and energy production.Fórmula:C4H6O5Peso molecular:134.09L-(-)-Malic acid
CAS:L-(-)-Malic acidFórmula:C4H6O5Pureza:98%Cor e Forma:White SolidPeso molecular:134.08743(S)-Malic acid
CAS:(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a naturally occurring dicarboxylic acid that is the source of the sweet and sour flavour of fruits.Fórmula:C4H6O5Pureza:99.72% - 99.98%Cor e Forma:White SolidPeso molecular:134.09L-(-)-Malic Acid
CAS:Applications The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
References Rindi, G., et al.: Biochem. J., 80, 214 (1961), Wolfgang, M., et al.: J. Biol. Chem., 281, 37265 (2006), Navarro, D., et al.: Metab. Brain Dis., 23, 115 (2008),Fórmula:C4H6O5Cor e Forma:NeatPeso molecular:134.09L-(-)-Malic acid
CAS:L-malic acid is a naturally occurring organic compound that can be found in many fruits and vegetables. It is an important intermediate in the citric acid cycle as well as a key component of the Krebs cycle. L-malic acid has been shown to have antiseizure and anti-inflammatory effects, and also inhibits the growth of bacteria such as Staphylococcus aureus. L-malic acid is synthesized from sodium carbonate and lactic acid by reacting with a mineral acid such as hydrochloric, sulfuric, or nitric acid. This reaction produces hydrogen gas, water, and l-malic acid. L-Malic Acid is also used for production of monoclonal antibodies against various targets, including human cells.
Fórmula:C4H6O5Cor e Forma:White Off-White PowderPeso molecular:134.09 g/mol
