CAS 998-06-1

1,2-Dilinoleoil-sn-glicero-3-fosfocolina

Descrição:

1,2-Dilinoleoil-sn-glicero-3-fosfocolina, comumente referido como DLPC, é um fosfolípido que desempenha um papel significativo nas membranas celulares e nas bicamadas lipídicas. É caracterizado por suas duas cadeias de ácidos graxos linoleoyl, que contribuem para sua fluidez e flexibilidade, tornando-o um componente importante na dinâmica de membranas. A molécula apresenta um esqueleto de glicerol, um grupo fosfato e um grupo cabeça de colina, que confere propriedades anfifílicas, permitindo que interaja com ambientes hidrofílicos e hidrofóbicos. O DLPC é frequentemente utilizado em estudos biofísicos e sistemas de entrega de medicamentos devido à sua capacidade de formar lipossomos e micelas. Suas propriedades estruturais permitem estabilizar estruturas de membrana e facilitar a incorporação de outras moléculas, como medicamentos ou proteínas, aumentando sua biodisponibilidade. Além disso, o DLPC é utilizado em várias aplicações de pesquisa, incluindo estudos sobre permeabilidade de membranas e o comportamento de bicamadas lipídicas sob diferentes condições. No geral, suas características únicas o tornam uma substância valiosa em contextos biológicos e farmacêuticos.

Fórmula: C₄₄H₈₀NO₈P

InChI: InChI=1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,42H,6-13,18-19,24-41H2,1-5H3/b16-14-,17-15-,22-20-,23-21-/t42-/m1/s1

Chave InChI: InChIKey=FVXDQWZBHIXIEJ-LNDKUQBDSA-N

SMILES: [C@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCC/C=C\C/C=C\CCCCC)=O

Sinónimos:

• (1,2-Dilinoleoyl)-3-lecithin
• (2R)-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
• (R-(All-Z))-(4-oxido-10-oxo-7-((1-oxooctadeca-9,12-dienyl)oxy)-3,5,9-trioxa-4-phosphaheptacosa-18,21-dienyl)trimethylammonium 4-oxide
• 1,2-Dilinoleoyl-sn-3-glycerophosphorylcholine
• 1,2-Dilinoleoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine
• 1,2-Dilinoleoyl-sn-glycerol-3-phosphocholine
• 1,2-Dilinoleoylphosphocholine
• 1-Linoleoyl-2-linoleoyl-sn-glycero-3-phosphorylcholine
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxo-9,12-octadecadienyl)oxy]-, hydroxide, inner salt, 4-oxide, [R-(all-Z)]-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxo-9,12-octadecadienyl)oxy]-, inner salt, 4-oxide, [R-(all-Z)]-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]oxy]-, inner salt, 4-oxide, (7R,18Z,21Z)-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z,12Z)-1-oxo-9,12-octadecadienyl]oxy]-, inner salt, 4-oxide, (7R,18Z,21Z)-
• 49: PN: WO2017201317 SEQID: 122 claimed RNA
• <span class="text-smallcaps">L</span>-(+)-α-(α′,β-Dilinoleoyl)-glycerylphosphorylcholine
• <span class="text-smallcaps">L</span>-Dilinoleoyllecithin
• <span class="text-smallcaps">L</span>-α-Dilinoleoyl phosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilinolein, <span class="text-smallcaps">L</span>-(+)-
• DLiPC
• Linolein, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide, inner salt, <span class="text-smallcaps">L</span>-(+)-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilinolein, L-(+)-

1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

CAS: 998-06-1

Fórmula: C₄₄H₈₀NO₈P

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 782.0817

Ref: IN-DA003W1P

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

CAS: 998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

Fórmula: C₄₄H₈₀NO₈P

Cor e Forma: Solid-Powder

Peso molecular: 782.08166

Ref: 54-BIL6001

1,2-Dilinoleoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 998-06-1

Fórmula: C44H80NO8P

Pureza: >98%

Cor e Forma: Solid

Peso molecular: 782.082

Ref: 48-37-1802

L-Dilinoleoyl Lecithin

CAS: 998-06-1

Fórmula: C₄₄H₈₀NO₈P

Peso molecular: 782.10

Ref: 4Z-C-59100

(R)-2,3-Bis((9Z,12Z)-octadeca-9,12-dienoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

CAS: 998-06-1

Pureza: ≥98%

Peso molecular: 782.0969849

Ref: 10-F791285

L-Dilinoleoyllecithin

Produto Controlado

CAS: 998-06-1

Fórmula: C₄₄H₈₀NO₈P

Cor e Forma: Neat

Peso molecular: 782.082

Ref: TR-D561175

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

CAS: 998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine (DLPC) is a phospholipid that is used in the treatment of insulin resistance and inflammation. DLPC is a stable molecule that exhibits intermolecular hydrogen bonding and has been shown to be effective against inflammatory diseases. DLPC has been used as a liposomal formulation for the treatment of type 2 diabetes by improving insulin sensitivity, which may be due to its ability to inhibit proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). It also binds to the receptor α, which are G protein coupled receptors present on cells involved in inflammatory responses. The binding of DLPC to these receptors leads to increased insulin sensitivity by inhibiting TNFα production.

Fórmula: C₄₄H₈₀NO₈P

Pureza: Min. 95%

Peso molecular: 782.08 g/mol

Ref: 3D-FD42822

L-Dilinoleoyllecithin

CAS: 998-06-1

L-Dilinoleoyllecithin is phosphatidylcholine. It is a glycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site.

Fórmula: C₄₄H₈₀NO₈P

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 782.08

Ref: TM-T24393