BTK
Os inibidores da tirosina quinase de Bruton (BTK) são compostos que especificamente têm como alvo e inibem a BTK, uma enzima crucial envolvida na sinalização do receptor de células B e na regulação da angiogênese. A BTK desempenha um papel significativo na proliferação e sobrevivência de células cancerígenas, particularmente em malignidades hematológicas. Ao inibir a BTK, esses compostos podem interromper a angiogênese e o crescimento tumoral, tornando-os valiosos na terapia do câncer. Na CymitQuimica, oferecemos uma gama de inibidores de BTK de alta qualidade para apoiar sua pesquisa em oncologia, imunologia e angiogênese.
Foram encontrados 145 produtos de "BTK"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ARQ 531
CAS:<p>ARQ-531: potent oral BTK inhibitor, anti-cancer potential, IC50 of 0.85/0.39 nM for WT/C481S-BTK.</p>Fórmula:C25H23ClN4O4Pureza:98.68% - 99.63%Cor e Forma:SolidPeso molecular:478.93AS-1763
CAS:<p>AS-1763 is an orally available and selective BTK inhibitor with an IC50 of 0.85 nM.</p>Fórmula:C33H31FN6O3Pureza:≥95%Cor e Forma:SolidPeso molecular:578.64Orelabrutinib
CAS:<p>Orelabrutinib (ICP-022) is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK).</p>Fórmula:C26H25N3O3Pureza:97.77% - 99.54%Cor e Forma:SolidPeso molecular:427.49Tirabrutinib hydrochloride
CAS:<p>Tirabrutinib hydrochloride is a potent, highly selective, irreversible oral BTK inhibitor.Cost-effective and quality-assured.</p>Fórmula:C25H23ClN6O3Pureza:99.04% - 99.27%Cor e Forma:SolidPeso molecular:490.94Rilzabrutinib
CAS:<p>Rilzabrutinib (PRN1008) is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK)(IC50 of 1.3 nM).</p>Fórmula:C36H40FN9O3Pureza:98.28% - 99.76%Cor e Forma:SolidPeso molecular:665.76MT-802
CAS:<p>MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802 has the potential to treat C481S mutant chronic lymphocytic leukemia (CLL).</p>Fórmula:C41H41N9O8Pureza:95.93% - 97%Cor e Forma:SolidPeso molecular:787.82Btk inhibitor 2
CAS:<p>Btk inhibitor 2 (BGB-3111 analog) is a BTK inhibitor.</p>Fórmula:C24H25N5O3Pureza:99.94%Cor e Forma:SolidPeso molecular:431.49IBT6A
CAS:<p>IBT6A is an impurity of Ibrutinib. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM). IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.</p>Fórmula:C22H22N6OPureza:99.8% - 99.88%Cor e Forma:SolidPeso molecular:386.45SJF620 hydrochloride
CAS:<p>SJF620 hydrochloride is a PROTAC that utilizes a lenalidomide analog to recruit CRBN and ligands to target Btk, exhibiting a DC50 of 7.9 nM [1].</p>Fórmula:C41H45ClN8O7Pureza:98%Cor e Forma:SolidPeso molecular:797.3FDA-Approved Kinase Inhibitor Library
<p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>Cor e Forma:LiquidDD 03-171
CAS:<p>Potent BTK Degrader, IC50=5.1nM, CRBN-dependent, suppresses MCL; degrades Ibrutinib-resistant BTK, no kinases binding, reduces tumors in models.</p>Fórmula:C55H62N10O8Cor e Forma:SolidPeso molecular:991.163BTK-IN-5
CAS:<p>BTK-IN-5 is a covalent inhibitor of Bruton's tyrosine kinase (BTK) designed for the treatment of medical conditions including cardiovascular diseases,</p>Fórmula:C23H32N4O5Cor e Forma:SolidPeso molecular:444.532GBD-9
CAS:<p>GBD-9, a dual-mechanism degrader, effectively promotes the degradation of BTK and GSPT1 through recruitment of E3 ligase cereblon (CRBN).</p>Fórmula:C44H47N9O6Pureza:98%Cor e Forma:SolidPeso molecular:797.9TLT8
<p>TLT8 is a ByeTAC protein degrader that targets BTK. It induces BTK degradation by non-covalently binding to Rpn-13 and BTK. TLT8 is applicable in research on chronic lymphocytic leukemia.</p>Cor e Forma:Odour SolidNRX-0492
CAS:<p>NRX-0492: orally active BTK degrader, induces ubiquitylation/proteasomal breakdown, potent with DC50 ≤0.2 nM, DC90 ≤0.5 nM, disrupts BCR signaling.</p>Fórmula:C43H51N11O6Cor e Forma:SolidPeso molecular:817.94PTD10
CAS:<p>PTD10, a highly potent PROTAC BTK degrader, exhibits a DC50 of 0.5 nM and a KD of 2.28 nM.</p>Fórmula:C49H51N11O8Pureza:98%Cor e Forma:SolidPeso molecular:922PROTAC BTK Degrader-1
CAS:<p>Potent, selective oral PROTAC BTK Degrader-1; IC50: 34.51 nM (WT), 64.56 nM (BTK-481S); reduces BTK protein, inhibits tumors.</p>Fórmula:C43H43N9O4Cor e Forma:SolidPeso molecular:749.86BTK ligand-14
<p>BTKligand-14 is a PROTAC-targeting ligand for BTK, suitable for the synthesis of FDU73.</p>Cor e Forma:Odour SolidBRK inhibitor P21d hydrochloride
CAS:<p>BRK inhibitor P21d HCl targets breast tumor kinase with 30 nM IC50, suppresses p-SAM68 at 52 nM, useful for in vivo breast cancer research.</p>Fórmula:C23H23ClFN7O2Cor e Forma:SolidPeso molecular:483.93Tyrosinase-IN-16
CAS:<p>Tyrosinase-IN-16 inhibited tyrosinase.</p>Fórmula:C8H6BrN3SPureza:99.57%Cor e Forma:SolidPeso molecular:256.12
