BTK
Os inibidores da tirosina quinase de Bruton (BTK) são compostos que especificamente têm como alvo e inibem a BTK, uma enzima crucial envolvida na sinalização do receptor de células B e na regulação da angiogênese. A BTK desempenha um papel significativo na proliferação e sobrevivência de células cancerígenas, particularmente em malignidades hematológicas. Ao inibir a BTK, esses compostos podem interromper a angiogênese e o crescimento tumoral, tornando-os valiosos na terapia do câncer. Na CymitQuimica, oferecemos uma gama de inibidores de BTK de alta qualidade para apoiar sua pesquisa em oncologia, imunologia e angiogênese.
Foram encontrados 168 produtos para "BTK".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
BMS-986142
CAS:BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).Fórmula:C32H30F2N4O4Pureza:99.44% - 99.76%Cor e Forma:SolidPeso molecular:572.6Ref: TM-T5138
1mg105,00€2mg165,00€5mg289,00€1mL*10mM (DMSO)358,00€10mg447,00€25mg715,00€50mg964,00€100mg1.243,00€200mg1.693,00€Fenebrutinib
CAS:Fenebrutinib (GDC-0853) is a selective and noncovalent Btk inhibitor (Ki: 0.91 nM).Fórmula:C37H44N8O4Pureza:98.26% - 98.94%Cor e Forma:SolidPeso molecular:664.8BTK IN-1
CAS:BTK IN-1 (SNS062 analog) (SNS062 analog) is an effective BTK inhibitor (IC50: <100 nM).Fórmula:C19H21ClN6OPureza:97.38%Cor e Forma:SolidPeso molecular:384.86Ref: TM-TQ0230
1mg35,00€2mg50,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg105,00€25mg170,00€50mg295,00€100mg416,00€Ibrutinib
CAS:Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.Fórmula:C25H24N6O2Pureza:98% - 99.95%Cor e Forma:White SolidPeso molecular:440.50(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Fórmula:C11H8Br2N2O2Pureza:99.88%Cor e Forma:SolidPeso molecular:360BIIB068
CAS:BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.Fórmula:C23H29N7O2Pureza:97.98%Cor e Forma:White SolidPeso molecular:435.52Ref: TM-T9192
1mg46,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg152,00€25mg264,00€50mg398,00€100mg532,00€200mg705,00€Ibrutinib deacryloylpiperidine
CAS:Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.Fórmula:C17H13N5OPureza:99.47%Cor e Forma:SolidPeso molecular:303.32CNX-774
CAS:CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50<1 nM).Fórmula:C26H22FN7O3Pureza:97.35% - 99.11%Cor e Forma:SolidPeso molecular:499.5Ref: TM-T2302
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)88,00€10mg119,00€25mg222,00€50mg369,00€100mg537,00€500mg1.161,00€PCI 29732
CAS:PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.Fórmula:C22H21N5OPureza:99.81%Cor e Forma:SolidPeso molecular:371.43ONO-4059 analog
CAS:ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Fórmula:C25H24N6O3Pureza:99.93%Cor e Forma:SolidPeso molecular:456.5Ref: TM-T6921
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg264,00€50mg439,00€100mg627,00€N-piperidine Ibrutinib
CAS:N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.Fórmula:C22H22N6OPureza:96.65%Cor e Forma:SolidPeso molecular:386.45(Rac)-IBT6A
CAS:(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Fórmula:C22H22N6OPureza:99.24%Cor e Forma:SolidPeso molecular:386.45Ref: TM-T10626
1mg44,00€2mg57,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg120,00€25mg215,00€50mg313,00€100mg439,00€200mg628,00€RN486
CAS:RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).Fórmula:C35H35FN6O3Pureza:99.38%Cor e Forma:SolidPeso molecular:606.69TL-895
CAS:TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).Fórmula:C25H26FN5O2Pureza:99.96%Cor e Forma:SolidPeso molecular:447.5Ref: TM-T9705
2mg39,00€5mg60,00€1mL*10mM (DMSO)60,00€10mg87,00€25mg172,00€50mg266,00€100mg391,00€200mg555,00€CHMFL-BMX-078
CAS:CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.Fórmula:C33H35N7O6Pureza:>99.99%Cor e Forma:SolidPeso molecular:625.67Remibrutinib
CAS:Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.Fórmula:C27H27F2N5O3Pureza:99.5% - 99.81%Cor e Forma:White SolidPeso molecular:507.53Ref: TM-T16730
1mg92,00€5mg210,00€1mL*10mM (DMSO)235,00€10mg340,00€25mg572,00€50mg713,00€100mg1.099,00€200mg1.485,00€(S)-Sunvozertinib
CAS:(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.Fórmula:C29H35ClFN7O3Pureza:99.64%Cor e Forma:SolidPeso molecular:584.08CGI-1746
CAS:CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.Fórmula:C34H37N5O4Pureza:97.69% - 97.88%Cor e Forma:White SolidPeso molecular:579.69Avitinib
CAS:Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Fórmula:C26H26FN7O2Pureza:99.81% - >99.99%Cor e Forma:White SolidPeso molecular:487.53zanubrutinib
CAS:Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK).Fórmula:C27H29N5O3Pureza:98.42% - 99.76%Cor e Forma:SolidPeso molecular:471.55Ref: TM-T7584
1mg52,00€2mg80,00€5mg124,00€1mL*10mM (DMSO)129,00€10mg215,00€25mg409,00€50mg612,00€100mg842,00€
