Syk
Os inibidores da Syk (tirosina quinase do baço) são compostos que têm como alvo a Syk, uma quinase envolvida na sinalização das células imunes e na regulação da angiogênese. A Syk desempenha um papel nas respostas inflamatórias que podem contribuir para a angiogênese tumoral. Inibir a Syk pode reduzir a formação de vasos sanguíneos induzida por inflamação em tumores, tornando esses inibidores valiosos na terapia contra o câncer e na pesquisa sobre inflamação. Na CymitQuimica, oferecemos uma ampla gama de inibidores de Syk de alta qualidade para apoiar sua pesquisa em imunologia, oncologia e angiogênese.
Foram encontrados 38 produtos para "Syk".
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Piceatannol
CAS:Fórmula:C14H12O4Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light red powder to crystalPeso molecular:244.25MNS
CAS:Fórmula:C9H7NO4Pureza:>98.0%(GC)Cor e Forma:Light yellow to Yellow to Green powder to crystalPeso molecular:193.163,4,3',5'-Tetrahydroxy-trans-stilbene
CAS:Fórmula:C14H12O4Pureza:97%Cor e Forma:SolidPeso molecular:244.2427Ref: IN-DA0002ZH
500gA consultar100mg25,00€250mg25,00€1g28,00€5g69,00€10g129,00€25g199,00€100g601,00€75g659,00€Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Fórmula:C9H11NO3·HClPureza:99.94%Cor e Forma:SolidPeso molecular:217.65Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Fórmula:C24H28N8O2Pureza:98.06% - 99.94%Cor e Forma:SolidPeso molecular:460.53Ref: TM-T14331
1mg39,00€5mg84,00€1mL*10mM (DMSO)85,00€10mg116,00€25mg178,00€50mg333,00€100mg495,00€200mg710,00€Lanraplenib
CAS:Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Fórmula:C23H25N9OPureza:98.35%Cor e Forma:SolidPeso molecular:443.5Ref: TM-T11824LL
1mg49,00€2mg71,00€5mg94,00€1mL*10mM (DMSO)109,00€10mg159,00€25mg275,00€50mg408,00€100mg600,00€Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Fórmula:C14H12O4Pureza:98.66% - 99.73%Cor e Forma:SolidPeso molecular:244.24Syk-IN-4
CAS:Syk-IN-4 is a potent, oral Syk inhibitor; blocks immune signaling; used for rheumatoid arthritis research.Fórmula:C21H25N9OCor e Forma:White SolidPeso molecular:419.48Ref: TM-T37077
1mg141,00€5mg335,00€1mL*10mM (DMSO)358,00€10mg597,00€25mg1.189,00€50mg1.935,00€100mg2.907,00€Tyrosine Kinase Inhibitor Library
A unique collection of xnum HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;Cor e Forma:Odour SolidRef: TM-L2200
1mgA consultar10μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultarSyk Kinase Peptide Substrate, Biotin labeled
The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.Fórmula:C76H108N18O24S1Cor e Forma:SolidPeso molecular:1689.9Cevidoplenib dimesylate
CAS:Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.Fórmula:C27H35N7O9S2Pureza:98%Cor e Forma:Yellow SolidPeso molecular:665.74Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].Fórmula:C26H31N9O4Pureza:98%Cor e Forma:SolidPeso molecular:533.58MRL-SYKi
MRL-SYKi is a highly selective and potent chemical probe for spleen tyrosine kinase (SYK). In live cell assays, it strongly binds to SYK gain-of-function (GoF) variants [SYK(S550Y), SYK(S550F), and SYK(P342T)], with IC50 values of 2.1 nM, 14 nM, and 4.6 nM in digitonin-permeabilized cell experiments. MRL-SYKi effectively reduces catalytic activity, as shown in PhosphoSens SOX peptide assays, where the IC50 for SYK(S550F) is 63 nM and for SYK(P342T) is 95 nM. Additionally, it decreases phosphorylation levels at Y525/526 of SYK(S550Y) in SW480 cells. MRL-SYKi is useful for inflammation research.Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Fórmula:C58H68N18O14Cor e Forma:SolidPeso molecular:1241.294TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Fórmula:C17H22ClFN6OPureza:99.28% - 99.82%Cor e Forma:SolidPeso molecular:380.85Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Fórmula:C23H24FN6O9P·2NaPureza:96.13% - 99.09%Cor e Forma:White SolidPeso molecular:624.42Ref: TM-T2605
1mg44,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)110,00€10mg117,00€25mg210,00€50mg354,00€100mg530,00€500mg1.153,00€Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Fórmula:C23H26FN6O9PPureza:93.08% - 99.58%Cor e Forma:SolidPeso molecular:580.46Ref: TM-T6115
1mg40,00€2mg54,00€5mg84,00€1mL*10mM (DMSO)96,00€10mg112,00€25mg198,00€50mg318,00€100mg520,00€500mg1.134,00€Entospletinib
CAS:Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Fórmula:C23H21N7OPureza:98.54% - 99.74%Cor e Forma:SolidPeso molecular:411.46Ref: TM-T6101
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg92,00€25mg166,00€50mg245,00€100mg394,00€200mg585,00€R406
CAS:R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Fórmula:C22H23FN6O5·C6H6O3SPureza:97.67% - 98.88%Cor e Forma:White SolidPeso molecular:628.63Ref: TM-T6174
1mg46,00€2mg57,00€5mg89,00€1mL*10mM (DMSO)120,00€10mg142,00€25mg299,00€50mg445,00€100mg647,00€
