Syk
Os inibidores da Syk (tirosina quinase do baço) são compostos que têm como alvo a Syk, uma quinase envolvida na sinalização das células imunes e na regulação da angiogênese. A Syk desempenha um papel nas respostas inflamatórias que podem contribuir para a angiogênese tumoral. Inibir a Syk pode reduzir a formação de vasos sanguíneos induzida por inflamação em tumores, tornando esses inibidores valiosos na terapia contra o câncer e na pesquisa sobre inflamação. Na CymitQuimica, oferecemos uma ampla gama de inibidores de Syk de alta qualidade para apoiar sua pesquisa em imunologia, oncologia e angiogênese.
Foram encontrados 39 produtos para "Syk".
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MNS
CAS:Fórmula:C9H7NO4Pureza:>98.0%(GC)Cor e Forma:Light yellow to Yellow to Green powder to crystalPeso molecular:193.16Piceatannol
CAS:Fórmula:C14H12O4Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light red powder to crystalPeso molecular:244.25Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Fórmula:C14H12O4Pureza:98.66% - 99.73%Cor e Forma:SolidPeso molecular:244.24Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Fórmula:C24H28N8O2Pureza:98.06% - 99.94%Cor e Forma:SolidPeso molecular:460.5315Lanraplenib
CAS:Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Fórmula:C23H25N9OPureza:98.35%Cor e Forma:SolidPeso molecular:443.5043Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Fórmula:C9H12ClNO3Pureza:99.94%Cor e Forma:SolidPeso molecular:217.649Syk-IN-4
CAS:Syk-IN-4 is a potent, oral Syk inhibitor; blocks immune signaling; used for rheumatoid arthritis research.Fórmula:C21H25N9OCor e Forma:White SolidPeso molecular:419.48Tyrosine Kinase Inhibitor Library
A unique collection of xnum HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;Cor e Forma:Odour SolidSyk Kinase Peptide Substrate, Biotin labeled
The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.Fórmula:C76H108N18O24S1Cor e Forma:SolidPeso molecular:1689.9Cevidoplenib dimesylate
CAS:Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.Fórmula:C27H35N7O9S2Pureza:98%Cor e Forma:Yellow SolidPeso molecular:665.738Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].Fórmula:C26H31N9O4Pureza:98%Cor e Forma:SolidPeso molecular:533.58MRL-SYKi
MRL-SYKi is a highly selective and potent chemical probe for spleen tyrosine kinase (SYK). In live cell assays, it strongly binds to SYK gain-of-function (GoF) variants [SYK(S550Y), SYK(S550F), and SYK(P342T)], with IC50 values of 2.1 nM, 14 nM, and 4.6 nM in digitonin-permeabilized cell experiments. MRL-SYKi effectively reduces catalytic activity, as shown in PhosphoSens SOX peptide assays, where the IC50 for SYK(S550F) is 63 nM and for SYK(P342T) is 95 nM. Additionally, it decreases phosphorylation levels at Y525/526 of SYK(S550Y) in SW480 cells. MRL-SYKi is useful for inflammation research.Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Fórmula:C58H68N18O14Cor e Forma:SolidPeso molecular:1241.2943,4,3',5'-Tetrahydroxy-trans-stilbene
CAS:Fórmula:C14H12O4Pureza:97%Cor e Forma:SolidPeso molecular:244.2427Ref: IN-DA0002ZH
100mg25,00€250mg28,00€1g31,00€5g69,00€10g129,00€25g197,00€75g660,00€100g700,00€500g2.090,00€Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Fórmula:C23H26FN6O9PPureza:93.08% - 99.58%Cor e Forma:SolidPeso molecular:580.4595PRT062607 hydrochloride
CAS:PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Fórmula:C19H24ClN9OPureza:97.7% - 99.81%Cor e Forma:SolidPeso molecular:429.907BAY 61-3606
CAS:BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibitingFórmula:C20H18N6O3Pureza:98.72%Cor e Forma:Yellow SolidPeso molecular:390.3953MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Cor e Forma:Yellow SolidPeso molecular:193.1562R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Fórmula:C16H13FN4O2Pureza:99.27% - 99.84%Cor e Forma:Yellow SolidPeso molecular:312.2984
