Syk
Os inibidores da Syk (tirosina quinase do baço) são compostos que têm como alvo a Syk, uma quinase envolvida na sinalização das células imunes e na regulação da angiogênese. A Syk desempenha um papel nas respostas inflamatórias que podem contribuir para a angiogênese tumoral. Inibir a Syk pode reduzir a formação de vasos sanguíneos induzida por inflamação em tumores, tornando esses inibidores valiosos na terapia contra o câncer e na pesquisa sobre inflamação. Na CymitQuimica, oferecemos uma ampla gama de inibidores de Syk de alta qualidade para apoiar sua pesquisa em imunologia, oncologia e angiogênese.
Foram encontrados 38 produtos para "Syk".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Fórmula:C23H26FN6O9PPureza:93.08% - 99.58%Cor e Forma:SolidPeso molecular:580.46Ref: TM-T6115
1mg40,00€2mg54,00€5mg84,00€1mL*10mM (DMSO)96,00€10mg112,00€25mg198,00€50mg318,00€100mg520,00€500mg1.134,00€Entospletinib
CAS:Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Fórmula:C23H21N7OPureza:98.54% - 99.74%Cor e Forma:SolidPeso molecular:411.46Ref: TM-T6101
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg92,00€25mg166,00€50mg245,00€100mg394,00€200mg585,00€R406
CAS:R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Fórmula:C22H23FN6O5·C6H6O3SPureza:97.67% - 98.88%Cor e Forma:White SolidPeso molecular:628.63Ref: TM-T6174
1mg46,00€2mg57,00€5mg89,00€1mL*10mM (DMSO)120,00€10mg142,00€25mg299,00€50mg445,00€100mg647,00€R406 free base
CAS:R406 free base (R406 (free base)) is a potent Syk inhibitor.Fórmula:C22H23FN6O5Pureza:97.64% - 99.11%Cor e Forma:White SolidPeso molecular:470.45PRT-060318
CAS:PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Fórmula:C18H24N6OPureza:99.98%Cor e Forma:White SolidPeso molecular:340.42Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Fórmula:C21H22O11Pureza:98.63% - 99.54%Cor e Forma:SolidPeso molecular:450.39PRT062607 hydrochloride
CAS:PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Fórmula:C19H23N9O·HClPureza:97.7% - 99.81%Cor e Forma:SolidPeso molecular:429.91Ref: TM-T2696
1mg57,00€2mg81,00€5mg120,00€1mL*10mM (DMSO)132,00€10mg177,00€25mg309,00€50mg475,00€200mg898,00€Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Fórmula:C20H27N7O3SPureza:98.74% - 99.49%Cor e Forma:SolidPeso molecular:445.54Ref: TM-T2487
1mg42,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)81,00€10mg101,00€25mg175,00€50mg268,00€100mg409,00€200mg573,00€500mg888,00€MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Cor e Forma:Yellow SolidPeso molecular:193.16Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Fórmula:C20H28ClN7O3SPureza:99.85%Cor e Forma:SolidPeso molecular:482Syk Inhibitor II
CAS:Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Fórmula:C14H15F3N6OPureza:97.63%Cor e Forma:SolidPeso molecular:340.3Sovleplenib
CAS:Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Fórmula:C24H30N6O3SPureza:99.71%Cor e Forma:SolidPeso molecular:482.6Ref: TM-T32088
1mg120,00€5mg289,00€1mL*10mM (DMSO)308,00€10mg434,00€25mg737,00€50mg1.153,00€100mg1.791,00€200mg2.412,00€Syk-IN-3
CAS:Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.Fórmula:C24H28N4O3SPureza:97.29% - 99.64%Cor e Forma:Yellow SolidPeso molecular:452.57ER-27319
CAS:ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFórmula:C20H22N2O5Pureza:98%Cor e Forma:SolidPeso molecular:370.4RO9021
CAS:RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).Fórmula:C18H25N7OPureza:99.90%Cor e Forma:SolidPeso molecular:355.44OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Fórmula:C18H15N3O3SPureza:98%Cor e Forma:SolidPeso molecular:353.39Lanraplenib monosuccinate
CAS:Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Fórmula:C27H31N9O5Pureza:98%Cor e Forma:SolidPeso molecular:561.59MK-8457
CAS:MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].Fórmula:C24H25F3N4O3SCor e Forma:SolidPeso molecular:506.54
