Syk
Os inibidores da Syk (tirosina quinase do baço) são compostos que têm como alvo a Syk, uma quinase envolvida na sinalização das células imunes e na regulação da angiogênese. A Syk desempenha um papel nas respostas inflamatórias que podem contribuir para a angiogênese tumoral. Inibir a Syk pode reduzir a formação de vasos sanguíneos induzida por inflamação em tumores, tornando esses inibidores valiosos na terapia contra o câncer e na pesquisa sobre inflamação. Na CymitQuimica, oferecemos uma ampla gama de inibidores de Syk de alta qualidade para apoiar sua pesquisa em imunologia, oncologia e angiogênese.
Foram encontrados 37 produtos de "Syk"
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Piceatannol
CAS:Fórmula:C14H12O4Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light red powder to crystalPeso molecular:244.25Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Fórmula:C24H28N8O2Pureza:98.06% - 99.94%Cor e Forma:SolidPeso molecular:460.53Ref: TM-T14331
1mg42,00€5mg88,00€10mg123,00€25mg188,00€50mg350,00€100mg522,00€200mg750,00€1mL*10mM (DMSO)116,00€Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Fórmula:C9H11NO3·HClPureza:99.94%Cor e Forma:SolidPeso molecular:217.651,3-Benzodioxole, 5-(2-nitroethenyl)-
CAS:Fórmula:C9H7NO4Pureza:98%Cor e Forma:SolidPeso molecular:193.1562Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Fórmula:C14H12O4Pureza:98.66% - 99.73%Cor e Forma:Light Tan To Yellow PowderPeso molecular:244.24Lanraplenib
CAS:Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Fórmula:C23H25N9OPureza:98.35%Cor e Forma:SolidPeso molecular:443.5Ref: TM-T11824LL
1mg51,00€2mg74,00€5mg99,00€10mg167,00€25mg290,00€50mg430,00€100mg633,00€1mL*10mM (DMSO)115,00€1,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-
CAS:Fórmula:C14H12O4Pureza:97%Cor e Forma:SolidPeso molecular:244.2427Tyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedCor e Forma:Odour SolidRef: TM-L2200
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarSyk Kinase Peptide Substrate, Biotin labeled
The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.Fórmula:C76H108N18O24S1Cor e Forma:SolidPeso molecular:1689.9Cevidoplenib dimesylate
CAS:<p>Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.</p>Fórmula:C27H35N7O9S2Pureza:98%Cor e Forma:SolidPeso molecular:665.74Syk-IN-7
<p>Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].</p>Fórmula:C26H31N9O4Pureza:98%Cor e Forma:SolidPeso molecular:533.58Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Fórmula:C58H68N18O14Cor e Forma:SolidPeso molecular:1241.294MNS
CAS:Fórmula:C9H7NO4Pureza:>98.0%(GC)Cor e Forma:Light yellow to Yellow to Green powder to crystalPeso molecular:193.16BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Fórmula:C20H18N6O3·2HClPureza:99.46%Cor e Forma:SolidPeso molecular:463.32Ref: TM-T6776
1mg38,00€5mg84,00€10mg116,00€25mg187,00€50mg279,00€100mg406,00€200mg565,00€1mL*10mM (DMSO)87,00€Fostamatinib
CAS:<p>Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.</p>Fórmula:C23H26FN6O9PPureza:93.08% - 99.38%Cor e Forma:SolidPeso molecular:580.46TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Fórmula:C17H22ClFN6OPureza:99.28% - 99.82%Cor e Forma:SolidPeso molecular:380.85Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Fórmula:C21H22O11Pureza:98.63% - 99.54%Cor e Forma:SolidPeso molecular:450.39PRT-060318
CAS:PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Fórmula:C18H24N6OPureza:99.98%Cor e Forma:SolidPeso molecular:340.42PRT062607 hydrochloride
CAS:PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Fórmula:C19H23N9O·HClPureza:97.7% - 99.81%Cor e Forma:SolidPeso molecular:429.91Ref: TM-T2696
1mg60,00€2mg86,00€5mg127,00€10mg187,00€25mg326,00€50mg500,00€200mg948,00€1mL*10mM (DMSO)139,00€BAY 61-3606
CAS:<p>BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting</p>Fórmula:C20H18N6O3Pureza:98.72%Cor e Forma:SolidPeso molecular:390.4Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Fórmula:C20H27N7O3SPureza:98.74% - 99.49%Cor e Forma:SolidPeso molecular:445.54Ref: TM-T2487
1mg42,00€2mg52,00€5mg74,00€10mg101,00€25mg175,00€50mg268,00€100mg409,00€200mg573,00€500mg888,00€1mL*10mM (DMSO)81,00€MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Cor e Forma:Yellow PowderPeso molecular:193.16R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Fórmula:C16H13FN4O2Pureza:99.27% - 99.84%Cor e Forma:SolidPeso molecular:312.3Ref: TM-T3185
1mg39,00€2mg51,00€5mg84,00€10mg124,00€25mg219,00€50mg329,00€100mg487,00€500mg1.026,00€1mL*10mM (DMSO)92,00€Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Fórmula:C23H24FN6O9P·2NaPureza:96.13% - 99.09%Cor e Forma:SolidPeso molecular:624.42Ref: TM-T2605
1mg47,00€2mg55,00€5mg88,00€10mg124,00€25mg221,00€50mg374,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)116,00€Entospletinib
CAS:Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Fórmula:C23H21N7OPureza:98.54% - 99.74%Cor e Forma:SolidPeso molecular:411.46Ref: TM-T6101
1mg38,00€2mg49,00€5mg81,00€10mg97,00€25mg170,00€50mg259,00€100mg416,00€200mg617,00€1mL*10mM (DMSO)88,00€R406
CAS:R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Fórmula:C22H23FN6O5·C6H6O3SPureza:97.67% - 98.82%Cor e Forma:SolidPeso molecular:628.63Ref: TM-T6174
1mg46,00€2mg57,00€5mg89,00€10mg142,00€25mg299,00€50mg445,00€100mg647,00€1mL*10mM (DMSO)120,00€R406 free base
CAS:R406 free base (R406 (free base)) is a potent Syk inhibitor.Fórmula:C22H23FN6O5Pureza:97.64% - 99.11%Cor e Forma:SolidPeso molecular:470.45Ref: TM-T2467
1mg47,00€5mg70,00€10mg97,00€25mg187,00€50mg338,00€100mg535,00€500mg1.121,00€1mL*10mM (DMSO)72,00€Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Fórmula:C20H28ClN7O3SPureza:99.85%Cor e Forma:SolidPeso molecular:482Syk Inhibitor II
CAS:Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Fórmula:C14H15F3N6OPureza:97.63%Cor e Forma:SolidPeso molecular:340.3ER-27319
CAS:ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFórmula:C20H22N2O5Pureza:98%Cor e Forma:SolidPeso molecular:370.4Sovleplenib
CAS:Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Fórmula:C24H30N6O3SPureza:99.71%Cor e Forma:SolidPeso molecular:482.6Ref: TM-T32088
1mg127,00€5mg305,00€10mg459,00€25mg777,00€50mg1.216,00€100mg1.890,00€200mg2.547,00€1mL*10mM (DMSO)324,00€RO9021
CAS:RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).Fórmula:C18H25N7OPureza:99.90%Cor e Forma:SolidPeso molecular:355.44Syk-IN-3
CAS:<p>Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.</p>Fórmula:C24H28N4O3SPureza:97.29% - >99.99%Cor e Forma:SolidPeso molecular:452.57OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Fórmula:C18H15N3O3SPureza:98%Cor e Forma:Dark Orange SolidPeso molecular:353.39Lanraplenib monosuccinate
CAS:Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Fórmula:C27H31N9O5Pureza:98%Cor e Forma:SolidPeso molecular:561.59MK-8457
CAS:MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].Fórmula:C24H25F3N4O3SCor e Forma:SolidPeso molecular:506.54Syk-IN-8
CAS:<p>Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.</p>Fórmula:C23H26N10Pureza:98%Cor e Forma:SolidPeso molecular:442.52
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