ASK
Os inibidores da quinase reguladora de apoptose (ASK) têm como alvo a família de quinases ASK, que são reguladores críticos das vias de apoptose e resposta ao estresse. As quinases ASK estão envolvidas na ativação da apoptose em resposta a vários sinais de estresse, incluindo estresse oxidativo e danos ao DNA. Ao inibir ASK, esses compostos podem modular a sinalização apoptótica, fornecendo ferramentas valiosas para pesquisas sobre morte celular, câncer e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma gama de inibidores de ASK de alta qualidade para apoiar sua pesquisa em apoptose, sinalização celular e mecanismos de doenças.
Foram encontrados 6 produtos de "ASK"
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Anti-DBF4 Antibody (2Q22)
<p>Anti-DBF4 Antibody (2Q22) is an antibody targeting DBF4. Anti-DBF4 Antibody (2Q22) can be used in ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200.</p>Cor e Forma:Odour LiquidASK1-IN-1
CAS:<p>ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.</p>Fórmula:C19H19N9O2Pureza:99.92%Cor e Forma:SolidPeso molecular:405.41MSC 2032964A
CAS:<p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>Fórmula:C16H13F3N6OPureza:99.76%Cor e Forma:SolidPeso molecular:362.31CDK8/19-IN-1
CAS:<p>CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).</p>Fórmula:C19H18N4O4S2Pureza:98%Cor e Forma:SolidPeso molecular:430.5ASK1-IN-8
CAS:<p>ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.</p>Fórmula:C26H32N8O2Cor e Forma:SolidPeso molecular:488.585ASK1-IN-7
CAS:<p>ASK1-IN-7 (Compound 4c) is an ASK1 inhibitor and a derivative of the ASK1 inhibitor scaffold 5-(5-Phenyl-furan-2-ylmethylene)-2-thioxo-thiazolidin-4-one. This compound is potentially applicable in research involving ASK1 signaling pathways, including studies on cellular stress response, inflammatory response, neurodegenerative diseases, and cardiovascular diseases.</p>Fórmula:C13H8N2O2S2Cor e Forma:SolidPeso molecular:288.345
