TNF
Gli inibitori del fattore di necrosi tumorale (TNF) sono composti che bloccano l'attività del TNF, una citochina coinvolta nell'infiammazione e nella regolazione dell'apoptosi. Il TNF può indurre l'apoptosi in alcuni tipi di cellule mentre promuove la sopravvivenza e l'infiammazione in altri. L'inibizione del TNF è cruciale nel trattamento delle malattie autoimmuni, delle condizioni infiammatorie croniche e di alcuni tipi di cancro. Gli inibitori del TNF aiutano a modulare la risposta immunitaria e a ridurre i danni ai tessuti causati da un'infiammazione eccessiva. Presso CymitQuimica, offriamo una vasta gamma di inibitori del TNF di alta qualità per supportare la tua ricerca in immunologia, infiammazione e apoptosi.
Foram encontrados 94 produtos de "TNF"
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Ozoralizumab
CAS:Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Pureza:SDS-PAGE:> 95%;SEC-HPLC:95.6%Cor e Forma:LiquidPeso molecular:38.44 kDaIscalimab
CAS:Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.Pureza:>95%Cor e Forma:LiquidPeso molecular:146.08 kDaTeneliximab
CAS:Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.Pureza:99.19% (SEC-HPLC) - >95.0% (SDS-PAGE)Cor e Forma:LiquidPeso molecular:146.06 kDaEnavatuzumab
CAS:Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.Pureza:>95%Cor e Forma:LiquidPeso molecular:150 kDaCertolizumab pegol
CAS:Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.Pureza:96.7% (SDS-PAGE); 96.5% (SEC-HPLC) - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:47.74 kDaUCB-9260
CAS:UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Fórmula:C26H25N5OPureza:98.39% - 99.24%Cor e Forma:SolidPeso molecular:423.51Ref: TM-T13951
1mg92,00€2mg133,00€5mg219,00€1mL*10mM (DMSO)245,00€10mg353,00€25mg602,00€50mg802,00€100mg1.108,00€200mg1.485,00€Utomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Fórmula:C17H24N8O3Pureza:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:142.77 kDa(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Fórmula:C27H39N5O7Pureza:97.61% - 99.72%Cor e Forma:SolidPeso molecular:545.63Ruplizumab
CAS:PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.Pureza:98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.42 kDaConatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:145.44 kDaLucatumumab
CAS:Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.Pureza:95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.15 kDaEJMC-1
CAS:EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.Fórmula:C17H11ClN2O4SPureza:98.38%Cor e Forma:SolidPeso molecular:374.8Ragifilimab
CAS:Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Cor e Forma:LiquidPeso molecular:146.46 kDaVarlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Pureza:SDS-PAGE:95% SEC-HPLC:98.65%Cor e Forma:LiquidPeso molecular:146 kDaTNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Fórmula:C17H14O4Pureza:99.21%Cor e Forma:SoildPeso molecular:282.29RO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Cor e Forma:Odour LiquidPamlectabart
Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.Pureza:95%Cor e Forma:LiquidPeso molecular:145.20 kDaTengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Cor e Forma:LiquidTNF-α Antagonist
CAS:TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction withFórmula:C58H71N11O15S2Cor e Forma:SolidPeso molecular:1226.39TNF-α (46-65), human
CAS:Human TNF alpha (46-65) peptide.Fórmula:C110H172N24O30Pureza:98%Cor e Forma:SolidPeso molecular:2310.69DSTYSLSSTLTLSK TFA
DSTYSLSSTLTLSK TFA detects infliximab, a chimeric IgG1 antibody targeting TNF-α.Fórmula:C66H108F3N15O28Cor e Forma:SolidPeso molecular:1616.64Acetyl tetrapeptide-2
CAS:Acetyl tetrapeptide-2 is a skin conditioner, by soothing and nourishing the skin through similar mechanisms as other peptides.Fórmula:C26H39N5O9Pureza:98%Cor e Forma:SolidPeso molecular:565.62KGYY15
CAS:KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Fórmula:C84H129N21O22SCor e Forma:SolidPeso molecular:1817.12MK-4166
MK-4166 is a humanized IgG1 agonistic monoclonal antibody targeting GITR. It is capable of enhancing the proliferation of both naive T lymphocytes and tumor-infiltrating T lymphocytes.Onercept
CAS:Onercept, a recombinant soluble form of the human tumor necrosis factor-alpha (TNF-α) p55 receptor, is utilized in the study of Crohn's disease [1].Cor e Forma:LiquidPegsunercept
CAS:Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].Cor e Forma:LiquidLenercept
CAS:Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Cor e Forma:LiquidEfaprinermin alfa
CAS:Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1].Cor e Forma:LiquidRanevetmab
CAS:Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.Cor e Forma:LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.Pureza:95%Cor e Forma:Odour LiquidPeso molecular:150 kDaOnfekafusp alfa
CAS:Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.Cor e Forma:LiquidTilogotamab
CAS:Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).Pureza:95%Cor e Forma:LiquidPeso molecular:144.88 kDaTanfanercept
CAS:Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.Cor e Forma:LiquidTelitacicept
CAS:Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligandCor e Forma:LiquidAsunercept
CAS:Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.Cor e Forma:LiquidZigakibart
CAS:Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)Pureza:95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.03 kDaBMS-986156
BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody that targets the glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR). It binds to GITR and enhances the activation of T effector cells while deactivating T regulatory cells. BMS-986156 is applicable for research in advanced solid tumors.Giloralimab
CAS:Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.Pureza:95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.34 kDaSym029
Sym029 is a human IgG monoclonal antibody (mAb) that targets TNFRSF5/CD40. It is applicable for cancer research. The suggested isotype control is Human IgG1 kappa, Isotype Control.Dazodalibep
CAS:Dazodalibep (MEDI 4920; VIB 4920) is a monoclonal antibody that specifically targets CD40LG/TNFSF5 and is fused to human serum albumin (ALB/HSA) [1].Cor e Forma:LiquidPlaculumab
CAS:Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.Cor e Forma:LiquidSotigalimab
CAS:Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.Pureza:98.50% - 98.50%Cor e Forma:LiquidPeso molecular:144.35 kDaTulinercept
CAS:Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1].Cor e Forma:LiquidTQB2916
TQB2916 is a humanized IgG2 monoclonal antibody agonist that targets CD40. It exhibits significant antitumor activity by occupying CD40 and activating immune function. TQB2916 is applicable for research in advanced solid tumors and lymphomas.Cor e Forma:Odour LiquidXmAb-2513
XmAb-2513 is a humanized monoclonal antibody inhibitor targeting CD30. It demonstrates significant anti-proliferative activity along with excellent antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP). XmAb-2513 is applicable in research on hematological malignancies such as Hodgkin lymphoma (HL) and anaplastic large cell lymphoma (ALCL).Cor e Forma:Odour LiquidMK-1248
MK-1248 is a human IgG4 monoclonal antibody (mAb) targeting TNFSF18. It enhances the proliferative response of tumor-infiltrating lymphocytes to anti-CD3 stimulation and promotes the production of anti-tumor associated regulatory cytokines. MK-1248 is utilized in research on solid tumors.Cor e Forma:Odour LiquidGSK2800528
GSK2800528 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa, utilized for research related to inflammation and psoriasis.Cor e Forma:Odour LiquidGB-223
GB-223 is a human monoclonal antibody (mAb) that targets TNFSF11/RANKL/CD254. It is applicable in the study of giant cell tumors of bone and postmenopausal osteoporosis.Cor e Forma:Odour LiquidIBI356
IBI356 is a humanized monoclonal antibody inhibitor that targets OX40L/CD134L/CD252. It can be utilized in the study of chronic inflammatory skin diseases, such as atopic dermatitis.Cor e Forma:Odour LiquidBC011
BC011 is a human monoclonal antibody (mAb) targeting TNFRSF1B. It enhances the proliferation of CD8+ T cells and depletes Treg cells, resulting in an increased proportion of effector T cells within the tumor microenvironment. BC011 is applicable in the study of tumor immunology.Cor e Forma:Odour Liquid
