Caspase
Os inibidores de caspases são compostos que bloqueiam a atividade das caspases, uma família de proteases que são executores centrais da apoptose. As caspases clivam substratos específicos dentro da célula para desencadear o processo apoptótico, levando à morte celular programada. Os inibidores de caspases são usados para estudar os mecanismos da apoptose, bem como para prevenir a morte celular indesejada em vários modelos de pesquisa. Esses inibidores também são explorados em contextos terapêuticos para proteger as células da apoptose em doenças como a neurodegeneração. Na CymitQuimica, oferecemos uma ampla gama de inibidores de caspases de alta qualidade para apoiar sua pesquisa em apoptose, morte celular e áreas relacionadas.
Foram encontrados 163 produtos para "Caspase".
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VRT-043198
CAS:VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.Fórmula:C22H29ClN4O6Cor e Forma:SolidPeso molecular:480.94ML132
CAS:ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).Fórmula:C22H28ClN5O5Cor e Forma:SolidPeso molecular:477.94Caspase-9 Inhibitor III
CAS:Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.Fórmula:C24H35ClN6O9Cor e Forma:SolidPeso molecular:587.02p-nitro-Pifithrin-α
CAS:p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.Fórmula:C15H16BrN3O3SCor e Forma:SolidPeso molecular:398.27SDZ 224-015
CAS:SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.Fórmula:C30H35Cl2N3O9Pureza:95.49% - 95.49%Cor e Forma:SolidPeso molecular:652.52ZYZ-488
CAS:ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.Fórmula:C20H29N3O11Pureza:99.04%Cor e Forma:White SolidPeso molecular:487.46QM31
CAS:QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).Fórmula:C39H38Cl4N4O4Pureza:98%Cor e Forma:SolidPeso molecular:768.56N1,N11-Diethylnorspermine
CAS:DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT & H2O2.Fórmula:C13H32N4Cor e Forma:SolidPeso molecular:244.42GRI977143
CAS:GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.Fórmula:C22H17NO4SPureza:99.08%Cor e Forma:SolidPeso molecular:391.44OT-82
CAS:OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Fórmula:C26H21FN4OPureza:98.91% - 99.31%Cor e Forma:Brown ViscousPeso molecular:424.47Ref: TM-T12330
2mg137,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg708,00€50mg1.108,00€100mg1.468,00€Anisperimus
CAS:Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.Fórmula:C18H39N7O3Pureza:98.10%Cor e Forma:White OilPeso molecular:401.55Caspase-3-IN-1
CAS:Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).Fórmula:C26H25N3O6SCor e Forma:SolidPeso molecular:507.56CAY10406
CAS:CAY10406, a trifluoromethyl isatin sulfonamide, selectively targets and inhibits caspase-3 and -7, key in apoptosis, with no data on its inhibition potency.Fórmula:C27H23F3N2O5SCor e Forma:SolidPeso molecular:544.54S1QEL1.1
CAS:S1QEL1.1 (S1QEL) is an electron leakage inhibitor that inhibits O2-induced ROS generation and prevents O2-induced DA closure.Fórmula:C23H24N4O3SPureza:99.93%Cor e Forma:White SolidPeso molecular:436.53Apoptotic agent-3
CAS:Apoptotic agent-3 is an apoptosis inducer; activates Caspase-3/7; antitumor proliferative activity; pharmacology research.Fórmula:C31H21N5OSPureza:99.31%Cor e Forma:Yellow SolidPeso molecular:511.62-chloro Palmitic Acid
CAS:2-chloro Palmitic acid triggers NETosis, elevates COX-2, adhesion molecules in HCAECs, and induces apoptosis and caspase-3 in THP-1 cells/monocytes.Fórmula:C16H31ClO2Cor e Forma:SolidPeso molecular:290.87Tigilanol tiglate
CAS:Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.Fórmula:C30H42O10Pureza:98%Cor e Forma:White SolidPeso molecular:562.65AD-2646
CAS:AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.Fórmula:C23H40N2O4Cor e Forma:SolidPeso molecular:408.57CZL55
CAS:CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Fórmula:C20H22N2O6Pureza:98.73%Cor e Forma:SolidPeso molecular:386.4EP1013
CAS:EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.Fórmula:C18H23FN2O6Pureza:98%Cor e Forma:SolidPeso molecular:382.38
