Caspase
Os inibidores de caspases são compostos que bloqueiam a atividade das caspases, uma família de proteases que são executores centrais da apoptose. As caspases clivam substratos específicos dentro da célula para desencadear o processo apoptótico, levando à morte celular programada. Os inibidores de caspases são usados para estudar os mecanismos da apoptose, bem como para prevenir a morte celular indesejada em vários modelos de pesquisa. Esses inibidores também são explorados em contextos terapêuticos para proteger as células da apoptose em doenças como a neurodegeneração. Na CymitQuimica, oferecemos uma ampla gama de inibidores de caspases de alta qualidade para apoiar sua pesquisa em apoptose, morte celular e áreas relacionadas.
Foram encontrados 163 produtos para "Caspase".
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Ivachtin
CAS:Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remainingFórmula:C20H21N3O7SPureza:99.74%Cor e Forma:White SolidPeso molecular:447.46Penicillic acid
CAS:Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.Fórmula:C8H10O4Pureza:98%Cor e Forma:Needles From Petroleum Ether Slight Yellow PowderPeso molecular:170.16Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Fórmula:C21H28O2Pureza:99.4% - 99.80%Cor e Forma:SolidPeso molecular:312.45Ref: TM-T5574
1mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg93,00€25mg152,00€50mg205,00€100mg289,00€200mg432,00€Z-VAD-FMK
CAS:Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does notFórmula:C21H28FN3O7Pureza:98.24% - 99.79%Cor e Forma:SolidPeso molecular:453.46Ref: TM-T7020
1mg112,00€5mg231,00€1mL*10mM (DMSO)255,00€10mg394,00€25mg627,00€50mg890,00€100mg1.198,00€200mg1.603,00€Tauroursodeoxycholate sodium
CAS:Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.Fórmula:C26H44NNaO6SPureza:97.90%Cor e Forma:SolidPeso molecular:521.69Senkyunolide I
CAS:1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.Fórmula:C12H16O4Pureza:99.73% - 99.88%Cor e Forma:SolidPeso molecular:224.25Ref: TM-T5S2076
1mg46,00€5mg84,00€1mL*10mM (DMSO)94,00€10mg102,00€25mg152,00€50mg222,00€100mg340,00€200mg504,00€Ossirene
CAS:Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.Fórmula:C2H4Cl3O2Te·H4NPureza:≥98%Cor e Forma:SolidPeso molecular:312.05Ref: TM-T6761
2mg39,00€5mg58,00€1mL*10mM (DMSO)66,00€10mg93,00€25mg138,00€50mg197,00€100mg294,00€200mg437,00€Aristolactam I
CAS:Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.Fórmula:C17H11NO4Pureza:98.98% - 99.96%Cor e Forma:Yellow SolidPeso molecular:293.27Ref: TM-T3S1227
1mg57,00€5mg133,00€1mL*10mM (DMSO)172,00€10mg205,00€25mg350,00€50mg515,00€100mg735,00€Z-FA-FMK
CAS:Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.Fórmula:C21H23FN2O4Pureza:98.84% - 99.68%Cor e Forma:White SolidPeso molecular:386.42Emricasan
CAS:Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.Fórmula:C26H27F4N3O7Pureza:98.13% - 99%Cor e Forma:White SolidPeso molecular:569.5Ref: TM-T5S2358
1mg49,00€2mg69,00€5mg105,00€1mL*10mM (DMSO)116,00€10mg137,00€25mg197,00€50mg295,00€100mg447,00€PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Fórmula:C22H26N4O3Pureza:98.82%Cor e Forma:SolidPeso molecular:394.47Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Fórmula:C16H10O7Pureza:98.07% - 99.87%Cor e Forma:SolidPeso molecular:314.25Ref: TM-T3384
1mg34,00€1mL*10mM (DMSO)50,00€5mg71,00€10mg109,00€25mg175,00€50mg314,00€100mg414,00€500mg954,00€Sesamolin
CAS:Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.Fórmula:C20H18O7Pureza:98.77% - 99.04%Cor e Forma:White SolidPeso molecular:370.35Ref: TM-T5S2283
1mg35,00€2mg50,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg120,00€25mg197,00€50mg294,00€100mg437,00€200mg622,00€Ac-DEVD-CHO acetate
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.Fórmula:C22H34N4O13Pureza:98.54%Cor e Forma:SolidPeso molecular:562.52BC-1471
CAS:BC-1471 is a STAMBP deubiquitinase inhibitor that blocks NALP7 inflammasome activity.Fórmula:C27H32N4O4SPureza:99.98%Cor e Forma:SolidPeso molecular:508.63Ref: TM-T8553
1mg58,00€5mg128,00€1mL*10mM (DMSO)144,00€10mg187,00€25mg323,00€50mg482,00€100mg658,00€200mg888,00€Z-IETD-FMK
CAS:Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.Fórmula:C30H43FN4O11Pureza:98% - 99.81%Cor e Forma:White SolidPeso molecular:654.68Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Fórmula:C22H24N2O7Pureza:99.79% - 99.92%Cor e Forma:SolidPeso molecular:428.44Ref: TM-T2S2362
1mg89,00€5mg205,00€1mL*10mM (DMSO)227,00€10mg334,00€25mg552,00€50mg782,00€100mg1.054,00€200mg1.414,00€Dehydrotrametenolic acid
CAS:Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation inFórmula:C31H48O3Pureza:98%Cor e Forma:SolidPeso molecular:468.71Limonin glucoside
CAS:Limonin glucoside: a citrus compound, blocks HIV/HTLV-1, triggers cancer cell death, kills Aedes larvae.Fórmula:C32H42O14Cor e Forma:SolidPeso molecular:650.674
