IAP
Os inibidores das proteínas inibidoras da apoptose (IAP) são compostos que bloqueiam a atividade das IAPs, uma família de proteínas que previnem a apoptose, inibindo caspases e outros componentes da maquinaria apoptótica. Os inibidores de IAP promovem a apoptose em células cancerígenas ao neutralizar esses sinais de sobrevivência, tornando-os ferramentas importantes na pesquisa e terapia contra o câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de IAP de alta qualidade para apoiar sua pesquisa em oncologia, apoptose e desenvolvimento terapêutico.
Foram encontrados 70 produtos para "IAP".
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MV1
CAS:MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.Fórmula:C33H44N4O5Pureza:99.86%Cor e Forma:SolidPeso molecular:576.73Ref: TM-T16163
2mg44,00€5mg67,00€1mL*10mM (DMSO)86,00€10mg112,00€25mg187,00€50mg280,00€100mg396,00€200mg522,00€SBP-0636457
CAS:SBP-0636457: SMAC mimetic, IAP inhibitor, binds BIR-domains (Ki=0.27μM), potential in tumor/cancer research.Fórmula:C25H36N4O4Cor e Forma:SolidPeso molecular:456.587XIAP BIR2/BIR2-3 inhibitor-3
CAS:XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].Fórmula:C86H106N18O16S2Cor e Forma:SolidPeso molecular:1712PROTAC KRAS G12C degrader-2
CAS:PROTAC KRAS G12C degrader-2 (compound 432) is a targeted modulator of K-Ras protein hydrolysis that functions as a bifunctional PROTAC molecule, incorporating a cereblon inhibitor of apoptosis proteins (IAP) ligand on one terminus and a KRAS-binding moiety on the opposite end, thereby enabling selective recruitment of mutant KRAS G12C to the ubiquitin–proteasome system for controlled degradation and mechanistic investigation of KRAS-driven oncogenic signaling pathways.Fórmula:C51H53ClFN9O7Cor e Forma:SolidPeso molecular:958.47XIAP BIR2/BIR2-3 inhibitor-2
CAS:XIAP BIR2/BIR2-3 Inhibitor-2 is a dual inhibitor of BIR2 and BIR2-3 with IC50 values less than 1 nM. It can be used in the study of cancers [1].Fórmula:C80H96N20O12Peso molecular:1529.75CST626
CAS:CST626 is a PROTAC degrader that targets XIAP, cIAP1, and cIAP2.Fórmula:C61H82N8O9SPureza:95.87%Cor e Forma:SolidPeso molecular:1103.42Dasminapant
CAS:APG-1387 inhibits IAPs, degrades cIAP1/2, XIAP, boosts chemosensitivity, and induces apoptosis in NPC.Fórmula:C60H72N10O10S2Cor e Forma:White SolidPeso molecular:1157.41MDM2/XIAP-IN-1
MDM2/XIAP-IN-1 (compound 14) is an orally active dual inhibitor of MDM2 and XIAP, exhibiting anti-cancer activity with an IC50 of 0.3 μM and potentialCor e Forma:Odour SolidSM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.Fórmula:C62H85ClN14O6Pureza:98%Cor e Forma:SolidPeso molecular:1157.88S2/IAPinh
S2/IAPinh is a conjugate composed of an inhibitor of apoptosis proteins inhibitor (IAPinh) and a ligand of sigma 2 SW43. It demonstrates anti-proliferative and apoptosis-inducing activity by degrading inhibitor of apoptosis proteins (clAP-1).Fórmula:C52H75Cl2FN6O6SCor e Forma:SolidPeso molecular:1000.48299XIAP BIR2/BIR2-3 inhibitor-1
CAS:XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) serves as a potent dual inhibitor targeting BIR2 and BIR2-3 domains, with IC50 values of 1.9 nM and 0.8 nM, respectively. This compound is utilized in cancer research studies [1].Fórmula:C72H96N16O14Cor e Forma:SolidPeso molecular:1409.63Anti-CD47 Antibody (4C168)
Anti-CD47 Antibody (4C168) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (4C168) can be used in IHC-P.Cor e Forma:Odour LiquidAnti-CD47 Antibody-FITC (9X161)
Anti-CD47 Antibody-FITC (9X161) is a FITC-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-FITC (9X161) can be used in FCM.Cor e Forma:Odour LiquidAnti-CD47 Antibody (6T428)
Anti-CD47 Antibody (6T428) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (6T428) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CD47 Antibody (9X161)
Anti-CD47 Antibody (9X161) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (9X161) can be used in FCM.Cor e Forma:Odour LiquidAnti-CD47 Antibody (5S892)
Anti-CD47 Antibody (5S892) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5S892) can be used in IHC-P.Cor e Forma:Odour LiquidAnti-CD47 Antibody (8K78)
Anti-CD47 Antibody (8K78) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (8K78) can be used in WB,ELISA,IP.Cor e Forma:Odour LiquidAnti-CD47 Antibody (5R542)
Anti-CD47 Antibody (5R542) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5R542) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CD47 Antibody-PE (9X161)
Anti-CD47 Antibody-PE (9X161) is a PE-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-PE (9X161) can be used in FCM.Cor e Forma:Odour LiquidAnti-CD47 Antibody (8A121)
Anti-CD47 Antibody (8A121) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (8A121) can be used in ELISA.Cor e Forma:Odour Liquid
