IAP
Os inibidores das proteínas inibidoras da apoptose (IAP) são compostos que bloqueiam a atividade das IAPs, uma família de proteínas que previnem a apoptose, inibindo caspases e outros componentes da maquinaria apoptótica. Os inibidores de IAP promovem a apoptose em células cancerígenas ao neutralizar esses sinais de sobrevivência, tornando-os ferramentas importantes na pesquisa e terapia contra o câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de IAP de alta qualidade para apoiar sua pesquisa em oncologia, apoptose e desenvolvimento terapêutico.
Foram encontrados 70 produtos para "IAP".
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Anti-ALPI Monoclonal Antibody (9M379)
Antibody Type: Mouse Monoclonal
Application: WB,FCM
Reactivity: HumanPeso molecular:Theoretical: 56.8 kDaLCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Fórmula:C26H33FN4O3SPureza:99.13% - 99.87%Cor e Forma:White SolidPeso molecular:500.629Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFórmula:C57H92O27Pureza:98.95% - ≥98%Cor e Forma:SolidPeso molecular:1209.3242Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFórmula:C42H56F2N8O6Pureza:97.08% - ≥95%Cor e Forma:SolidPeso molecular:806.9408Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Fórmula:C17H26O4Pureza:97.07% - 99.95%Cor e Forma:Orange SolidPeso molecular:294.39GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Fórmula:C25H34N6O3SPureza:97.18% - 99.32%Cor e Forma:SolidPeso molecular:498.64BV6
CAS:BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Fórmula:C70H96N10O8Pureza:97.46% - 99.82%Cor e Forma:SolidPeso molecular:1205.57344-Methylsalicylic acid
CAS:4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Fórmula:C8H8O3Pureza:99.64%Cor e Forma:White SolidPeso molecular:152.1473Xevinapant
CAS:Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Fórmula:C32H43N5O4Pureza:98% - 99.94%Cor e Forma:SolidPeso molecular:561.7149SM-164
CAS:SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Fórmula:C62H84N14O6Pureza:96.8% - 99.92%Cor e Forma:SolidPeso molecular:1121.4207Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Fórmula:C15H16O3Pureza:98.76%Cor e Forma:SolidPeso molecular:244.2857AZD5582 acetate
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Fórmula:C60H82N8O10Pureza:97.76% - 99.94%Cor e Forma:White SolidPeso molecular:1075.36ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Fórmula:C30H42FN5O3Pureza:98.33% - 99.85%Cor e Forma:White SolidPeso molecular:539.6846MX69
CAS:MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Fórmula:C27H26N2O4SPureza:97.27% - 99.57%Cor e Forma:SolidPeso molecular:474.571CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Cor e Forma:Lyophilized PowderPeso molecular:60-90 KDa (reducing condition)CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:60-70 KDa (reducing condition)CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.Cor e Forma:Lyophilized PowderPeso molecular:33-55 KDa (reducing condition)MDM2/XIAP-IN-3
CAS:MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFórmula:C29H30N2O5SCor e Forma:SolidPeso molecular:518.62NOC-5
CAS:NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.Fórmula:C6H16N4O2Pureza:98%Cor e Forma:White SolidPeso molecular:176.22T-3256336
CAS:T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Fórmula:C31H45F2N5O5Pureza:98%Cor e Forma:SolidPeso molecular:605.72
