IAP
Os inibidores das proteínas inibidoras da apoptose (IAP) são compostos que bloqueiam a atividade das IAPs, uma família de proteínas que previnem a apoptose, inibindo caspases e outros componentes da maquinaria apoptótica. Os inibidores de IAP promovem a apoptose em células cancerígenas ao neutralizar esses sinais de sobrevivência, tornando-os ferramentas importantes na pesquisa e terapia contra o câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de IAP de alta qualidade para apoiar sua pesquisa em oncologia, apoptose e desenvolvimento terapêutico.
Foram encontrados 66 produtos de "IAP"
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CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
<p>CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.</p>Cor e Forma:Lyophilized PowderPeso molecular:15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
<p>CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:40.6 kDa (predicted)CD47 Protein, Human, Recombinant
<p>CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.</p>Pureza:97.8%Cor e Forma:Lyophilized PowderPeso molecular:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase Protein, Human, Recombinant (His)
<p>Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:98.4%Cor e Forma:Lyophilized PowderPeso molecular:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)Embelin
CAS:<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Fórmula:C17H26O4Pureza:97.07% - 99.88%Cor e Forma:SolidPeso molecular:294.39GDC-0152
CAS:<p>GDC-0152 is a potent inhibitor of IAPs.</p>Fórmula:C25H34N6O3SPureza:97.18% - 99.32%Cor e Forma:SolidPeso molecular:498.64Birinapant
CAS:<p>Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of</p>Fórmula:C42H56F2N8O6Pureza:97.08% - ≥95%Cor e Forma:SolidPeso molecular:806.94ASTX660
CAS:<p>Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.</p>Fórmula:C30H42FN5O3Pureza:98.33% - 99.85%Cor e Forma:SolidPeso molecular:539.68Xevinapant
CAS:<p>Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.</p>Fórmula:C32H43N5O4Pureza:98% - 99.94%Cor e Forma:SolidPeso molecular:561.71LCL161
CAS:<p>LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C26H33FN4O3SPureza:99.13% - 99.87%Cor e Forma:SolidPeso molecular:500.63Isolinderalactone
CAS:<p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>Fórmula:C15H16O3Pureza:99.62%Cor e Forma:SolidPeso molecular:244.29Polygalacin D
CAS:<p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>Fórmula:C57H92O27Pureza:98.95% - ≥98%Cor e Forma:SolidPeso molecular:1209.44-Methylsalicylic acid
CAS:<p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>Fórmula:C8H8O3Pureza:99.64%Cor e Forma:Solid Solid CrystallinePeso molecular:152.15SM-164
CAS:<p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>Fórmula:C62H84N14O6Pureza:98.53% - 99.92%Cor e Forma:SolidPeso molecular:1121.42MX69
CAS:<p>MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.</p>Fórmula:C27H26N2O4SPureza:97.27% - 99.57%Cor e Forma:SolidPeso molecular:474.57BV6
CAS:<p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>Fórmula:C70H96N10O8Pureza:97.46% - 99.82%Cor e Forma:SolidPeso molecular:1205.57AZD5582 acetate (1258392-53-8 free base)
<p>AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.</p>Fórmula:C60H82N8O10Pureza:97.76%Cor e Forma:SolidPeso molecular:1075.36T-3256336
CAS:<p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>Fórmula:C31H45F2N5O5Pureza:98%Cor e Forma:SolidPeso molecular:605.72MX107
CAS:<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Fórmula:C24H28N2O2Cor e Forma:SolidPeso molecular:376.49A 410099.1
CAS:<p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>Fórmula:C27H41ClN4O3Pureza:99.30%Cor e Forma:SolidPeso molecular:505.1
