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IAP

IAP

Os inibidores das proteínas inibidoras da apoptose (IAP) são compostos que bloqueiam a atividade das IAPs, uma família de proteínas que previnem a apoptose, inibindo caspases e outros componentes da maquinaria apoptótica. Os inibidores de IAP promovem a apoptose em células cancerígenas ao neutralizar esses sinais de sobrevivência, tornando-os ferramentas importantes na pesquisa e terapia contra o câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de IAP de alta qualidade para apoiar sua pesquisa em oncologia, apoptose e desenvolvimento terapêutico.

Foram encontrados 66 produtos de "IAP"

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  • Isolinderalactone
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    Isolinderalactone

    CAS:
    <p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>
    Fórmula:C15H16O3
    Pureza:99.62%
    Cor e Forma:Solid
    Peso molecular:244.29

    Ref: TM-T8213

  • Polygalacin D
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    Polygalacin D

    CAS:
    <p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>
    Fórmula:C57H92O27
    Pureza:98.95% - ≥98%
    Cor e Forma:Solid
    Peso molecular:1209.4

    Ref: TM-TN2091

  • 4-Methylsalicylic acid
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    4-Methylsalicylic acid

    CAS:
    <p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>
    Fórmula:C8H8O3
    Pureza:99.64%
    Cor e Forma:Solid Solid Crystalline
    Peso molecular:152.15

    Ref: TM-T22225

  • SM-164
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    SM-164

    CAS:
    <p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>
    Fórmula:C62H84N14O6
    Pureza:98.53% - 99.92%
    Cor e Forma:Solid
    Peso molecular:1121.42

    Ref: TM-T12932L

  • MX69
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    MX69

    CAS:
    <p>MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.</p>
    Fórmula:C27H26N2O4S
    Pureza:97.27% - 99.57%
    Cor e Forma:Solid
    Peso molecular:474.57

    Ref: TM-T3653

  • BV6
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    BV6

    CAS:
    <p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>
    Fórmula:C70H96N10O8
    Pureza:97.46% - 99.82%
    Cor e Forma:Solid
    Peso molecular:1205.57

    Ref: TM-T6428

  • AZD5582 acetate (1258392-53-8 free base)
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    AZD5582 acetate (1258392-53-8 free base)

    <p>AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.</p>
    Fórmula:C60H82N8O10
    Pureza:97.76%
    Cor e Forma:Solid
    Peso molecular:1075.36

    Ref: TM-T14378L

  • T-3256336
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    T-3256336

    CAS:
    <p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>
    Fórmula:C31H45F2N5O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:605.72

    Ref: TM-T26246

  • MX107
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    MX107

    CAS:
    <p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>
    Fórmula:C24H28N2O2
    Cor e Forma:Solid
    Peso molecular:376.49

    Ref: TM-T69845

  • A 410099.1
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    A 410099.1

    CAS:
    <p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>
    Fórmula:C27H41ClN4O3
    Pureza:99.30%
    Cor e Forma:Solid
    Peso molecular:505.1

    Ref: TM-T36890

  • MDM2/XIAP-IN-3
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    MDM2/XIAP-IN-3

    CAS:
    <p>MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing</p>
    Fórmula:C29H30N2O5S
    Cor e Forma:Solid
    Peso molecular:518.62

    Ref: TM-T79483

  • CUDC-427
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    CUDC-427

    CAS:
    <p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>
    Fórmula:C29H36N6O4S
    Pureza:99.92%
    Cor e Forma:Solid
    Peso molecular:564.7

    Ref: TM-T15018

  • Anticancer agent 128
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    Anticancer agent 128

    CAS:
    <p>Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19</p>
    Fórmula:C26H38N4O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:470.6

    Ref: TM-T79248

  • Anticancer agent 127
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    Anticancer agent 127

    CAS:
    <p>Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,</p>
    Fórmula:C26H37FN4O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:552.66

    Ref: TM-T79247

  • Logotipo do CymitQuimica
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    XIAP degrader-1

    <p>XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).</p>
    Fórmula:C34H45N5O4
    Cor e Forma:Solid
    Peso molecular:587.75

    Ref: TM-T64161

  • Logotipo do CymitQuimica
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    XIAP/cIAP1 antagonist-1

    <p>Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.</p>
    Cor e Forma:Solid

    Ref: TM-T64302