Survivina
Os inibidores de survivina têm como alvo a proteína survivina, um membro da família de inibidores da apoptose (IAP) que é altamente expressa em células cancerígenas e as ajuda a evitar a apoptose. A survivina desempenha um papel crucial na regulação do ciclo celular e na inibição da apoptose, tornando-a um alvo crítico na terapia do câncer. Ao inibir a survivina, esses compostos podem promover a apoptose em células cancerígenas, oferecendo potenciais benefícios terapêuticos. Na CymitQuimica, oferecemos uma seleção de inibidores de survivina de alta qualidade para apoiar sua pesquisa em oncologia, apoptose e desenvolvimento terapêutico.
Foram encontrados 14 produtos de "Survivina"
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MNK8
CAS:MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.Fórmula:C15H12N2O2Pureza:99.74%Cor e Forma:SolidPeso molecular:252.27ZLDI-8
CAS:ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.
Fórmula:C24H23N3O3SPureza:98.09%Cor e Forma:SolidPeso molecular:433.52MX106-4C
MX106-4C is a survivin inhibitor that selectively targets ABCB1-positive colorectal cancer cells. It can work synergistically with Doxorubicin for enhanced anticancer effects or restore Doxorubicin sensitivity in drug-resistant ABCB1 cells.Fórmula:C23H25BrN2O2Peso molecular:440.10994HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Cor e Forma:Lyophilized PowderPeso molecular:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.NSC 80467
CAS:NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.Fórmula:C24H22BrN3O5Pureza:99.25%Cor e Forma:SolidPeso molecular:512.35HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Cor e Forma:Lyophilized PowderPeso molecular:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on Tris-Bis PAGE result.HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Cor e Forma:Lyophilized PowderPeso molecular:The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.LQZ-7I
CAS:LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumorsFórmula:C20H14F2N4Pureza:99.81% - 99.87%Cor e Forma:SolidPeso molecular:348.35Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Fórmula:C15H16O3Pureza:98.76%Cor e Forma:SolidPeso molecular:244.291-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.Fórmula:C21H13ClF3N3O2Pureza:99.41%Cor e Forma:SolidPeso molecular:431.8Ref: TM-T22424
1mg42,00€2mg55,00€5mg88,00€10mg127,00€25mg264,00€50mg432,00€100mg622,00€200mg873,00€1mL*10mM (DMSO)99,00€Sepantronium bromide
CAS:Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
Fórmula:C20H19BrN4O3Pureza:99.68% - 99.85%Cor e Forma:SolidPeso molecular:443.26GDP366
CAS:GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.Fórmula:C20H17N5OSPureza:98.78% - 99.84%Cor e Forma:SolidPeso molecular:375.45AQIM-I
CAS:AQIM-I is a survivin inhibitor that reduces survivin expression and colony formation. It promotes reactive oxygen species (ROS) production, apoptosis, cell cycle arrest, DNA damage, and autophagy. Moreover, AQIM-I effectively inhibits nonsmall cell lung cancer cells A549, with an IC 50 value of 9 nM [1].
Fórmula:C17H13IN2O2Cor e Forma:SolidPeso molecular:404.20
