Cinesina
Os inibidores de cinesina têm como alvo as proteínas motoras cinesinas, que são responsáveis pelo transporte de carga celular ao longo dos microtúbulos e desempenham um papel crucial na divisão celular, particularmente durante a mitose. As cinesinas estão envolvidas no movimento de cromossomos e outras organelas durante a divisão celular. Inibir as cinesinas pode interromper esses processos, levando à parada do ciclo celular e possível morte celular, tornando esses inibidores valiosos na pesquisa do câncer. Na CymitQuimica, oferecemos uma gama diversificada de inibidores de cinesina de alta qualidade para apoiar sua pesquisa em biologia celular, mitose e terapia do câncer.
Foram encontrados 68 produtos de "Cinesina"
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Mps1-IN-1 dihydrochloride
CAS:Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.Fórmula:C28H35Cl2N5O4SCor e Forma:SolidPeso molecular:608.58ARQ 621
CAS:<p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>Fórmula:C28H24Cl2FN5O2Pureza:97.01% - 98.38%Cor e Forma:SolidPeso molecular:552.43Mps1-IN-3 hydrochloride
<p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>Fórmula:C26H32ClN7O4SCor e Forma:SolidPeso molecular:574.09BTB-1
CAS:BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.Fórmula:C12H8ClNO4SPureza:99.71%Cor e Forma:SolidPeso molecular:297.71Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Fórmula:C16H18N2O2SPureza:98.07%Cor e Forma:SolidPeso molecular:302.39BRD9876
CAS:<p>BRD9876 is a selective inhibitor of MM1S growth.</p>Fórmula:C16H14N2Pureza:97.81%Cor e Forma:SolidPeso molecular:234.3Empesertib
CAS:<p>Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.</p>Fórmula:C29H26FN5O4SPureza:97.45% - 99.4%Cor e Forma:SolidPeso molecular:559.61S-trityl-L-Cysteine
CAS:<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Fórmula:C22H21NO2SPureza:97.02%Cor e Forma:Almost White To Light Yellow Granular PowderPeso molecular:363.47CW-069
CAS:<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Cor e Forma:SolidPeso molecular:500.33SB-743921 hydrochloride
CAS:<p>SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).</p>Fórmula:C31H34Cl2N2O3Pureza:95.58% - 99.70%Cor e Forma:SolidPeso molecular:553.52Monastrol
CAS:<p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>Fórmula:C14H16N2O3SPureza:98.02% - 98.59%Cor e Forma:SolidPeso molecular:292.35AZ3146
CAS:<p>AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.</p>Fórmula:C24H32N6O3Pureza:97.84% - >99.99%Cor e Forma:SolidPeso molecular:452.55K858 (Racemic)
CAS:<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Fórmula:C13H15N3O2SPureza:>99.99%Cor e Forma:SolidPeso molecular:277.34GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Cor e Forma:SolidPeso molecular:592.13Mps1-IN-2
CAS:<p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Cor e Forma:SolidPeso molecular:480.6BAY1217389
CAS:<p>BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).</p>Fórmula:C27H24F5N5O3Pureza:98.14% - 99.42%Cor e Forma:SolidPeso molecular:561.5Mps1-IN-1
CAS:<p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>Fórmula:C28H33N5O4SPureza:98.33%Cor e Forma:SolidPeso molecular:535.66Mps1-IN-4
CAS:<p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>Fórmula:C26H31F3N6O2Cor e Forma:SolidPeso molecular:516.56KIF18A-IN-3
CAS:<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Fórmula:C28H38N4O5S2Pureza:98.45%Cor e Forma:SolidPeso molecular:574.76Mps-BAY2b
CAS:<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Fórmula:C20H23N5OCor e Forma:SolidPeso molecular:349.43
